Change in HbA1c. A: Change in HbA1c (%) from baseline to 12, 24, and 36 months following randomization to medical/lifestyle, RYGB, SG, or AGB. Least-squares means and corresponding SEs from a repeated-measures model are plotted. Black dotted line with black circles indicates combined effects of surgical intervention. Surgery lowered HbA1c to a greater extent than medical/lifestyle intervention. B: Percent change in body weight from baseline to 12, 24, and 36 months following randomization to medical/lifestyle, RYGB, SG, or AGB. Least-squares means and corresponding SEs from a repeated-measures model are plotted. Black dotted line with black circles indicates combined effects of surgical intervention. Surgery lowered body weight to a greater extent than medical/lifestyle intervention. C: Percentage of patients taking diabetes medication at baseline and 3 years following surgery or medical/lifestyle intervention. LAGB, laparoscopic AGB.