A: Change in body weight during exenatide and placebo treatment periods. Error bars represent ± SEM. P < 0.02 at 2 weeks. B: Individual weight profiles during exenatide treatment among high responders (n = 11). C: Individual weight profiles during exenatide treatment among moderate responders (n = 14). D: Individual weight profiles during exenatide treatment among nonresponders (n = 12).