Time-dependent HRs for all cause-mortality (left) and myocardial infarction (right) from 0 to 20 years after diagnosis of type 2 diabetes, assuming a one percentage unit lower HbA1c from diagnosis (green dotted lines), and when the same degree of HbA1c lowering was imposed from 5 years (blue dashed lines), and from 10 years (red solid lines) after diagnosis. The shaded regions represent 95% confidence limits. HRs were calculated according to Eq. 6 in the Supplementary Material.