Illustration of changes over time of insulin requirements in 20 of the 33 patients pancreatectomized for diffuse congenital hyperinsulinism. Four upper bars: Patients with insulin immediately after surgery but transiently. The three following bars: Patients with insulin after a delay but transiently. Thirteen lower bars: Patients with insulin after a delay and definitively. The other patients are not presented: eight with insulin immediately after surgery and definitively, with no insulin treatment (including five who received insulin immediately after surgery for 1–16 days). Dark bars, time of insulin therapy; gray bars, time of follow-up, with hyperglycemia but without insulin. yr, years.