Distribution of annual unadjusted and adjusted eGFR slopes from best linear unbiased predictions by diabetes status. Short dashed line, no diabetes; dashed line, undiagnosed diabetes; and solid line, diagnosed diabetes. Adjusted for the following characteristics at baseline and their interactions with time, continuous variables centered at their means: age (reference: 54.67 years), sex (reference: male; and female), race–center (reference: Forsyth County, NC–white; and Forsyth County, NC–black, Jackson, MS–black, Minneapolis, MN–white, and Washington County, MD–white), systolic blood pressure (reference: 121.22 mmHg), hypertension medication use (reference: no; and yes), BMI (reference: 27.68 kg/m2), HDL (reference: 51.60 mg/dL), prevalent coronary heart disease (reference: no; and yes), smoking status (reference: never; and former and current), annual family income (reference: <$25,000; and ≥$25,000), and educational status (reference: high school; and less than high school, vocational school, college, and graduate/professional school).