. | Total (N = 386) . | Study . | Birth weight . | ||||
---|---|---|---|---|---|---|---|
CONCEPTT (n = 200) . | Sweden (n = 186) . | Statistic (P) . | LGA (n = 232) . | Non-LGA (n = 154) . | Statistic (P) . | ||
Age, years, mean (SD) | 37.21 (1.87) | 36.97 (1.69) | 37.49 (2.03) | −2.73 (1.00) | 37.14 (1.63) | 37.34 (2.19) | 0.99 (0.84) |
European descent, n (%) | 346 (90) | 178 (89) | 173 (93) | −1.37 (0.17) | 206 (89) | 145 (94) | 1.80 (0.07) |
Diabetes duration, years, mean (SD) | 15.95 (7.89) | 16.49 (7.66) | 15.39 (8.12) | 1.36 (0.91) | 16.13 (7.89) | 15.69 (7.89) | −0.54 (0.70) |
Insulin delivery by pump, n (%) | 144 (37) | 90 (45) | 54 (29) | 3.24 (<0.01) | 94 (41) | 50 (32) | −1.60 (0.11) |
First trimester HbA1c, mmol/mol, mean (SD) | 56.6 (9.9) | 57.1 (7.8) | 55.7 (12.4) | 1.30 (0.19) | 56.9 (9.9) | 56.1 (9.9) | −0.71 (0.48) |
First trimester HbA1c, %, mean (SD) | 7.3 (1.6) | 7.4 (1.4) | 7.2 (1.9) | 1.30 (0.19) | 7.4 (1.6) | 7.3 (1.6) | −0.71 (0.48) |
BMI, kg/m2, mean (SD) | 25.8 (4.6) | 25.7 (4.6) | 25.9 (4.7) | −0.34 (0.73) | 25.9 (4.7) | 25.4 (4.4) | −0.33 (0.74) |
Primiparous, n (%) | 187 (48) | 98 (49) | 89 (48) | 0.22 (0.82) | 66 (28) | 121 (78) | 0.08 (0.93 |
Gestation birth, weeks, mean (SD) | 37.2 (1.9) | 36.9 (1.7) | 37.5 (2.0) | −3.18 (<0.01) | 37.0 (1.6) | 37.3 (2.2) | −1.55 (0.12) |
Preterm delivery <37 weeks, n (%) | 132 (34) | 80 (40) | 52 (28) | 2.49 (0.01) | 83 (36) | 49 (32) | −0.80 (0.42) |
Caesarean section, n (%) | 224 (58) | 137 (69) | 87 (47) | 4.32 (<0.01) | 150 (65) | 74 (48) | −3.24 (<0.01) |
Birth weight, kg, mean (SD) | 3.69 (0.72) | 3.56 (0.71) | 3.82 (0.72) | 3.47 (<0.01) | 4.00 (0.55) | 3.00 (0.57) | −12.94 (<0.01) |
Birth weight percentile, mean (SD)* | 82.7 (24.7) | 82.0 (25.8) | 83.6 (23.4) | −0.64 (0.52) | 98.1 (2.67) | 59.6 (25.0) | −23.22 (<0.01) |
LGA ≥90th percentile, n (%) | 232 (60) | 122 (61) | 110 (59) | −1.17 (0.24) | 225 (97) | 7 (26) | −14.73 (<0.01) |
. | Total (N = 386) . | Study . | Birth weight . | ||||
---|---|---|---|---|---|---|---|
CONCEPTT (n = 200) . | Sweden (n = 186) . | Statistic (P) . | LGA (n = 232) . | Non-LGA (n = 154) . | Statistic (P) . | ||
Age, years, mean (SD) | 37.21 (1.87) | 36.97 (1.69) | 37.49 (2.03) | −2.73 (1.00) | 37.14 (1.63) | 37.34 (2.19) | 0.99 (0.84) |
European descent, n (%) | 346 (90) | 178 (89) | 173 (93) | −1.37 (0.17) | 206 (89) | 145 (94) | 1.80 (0.07) |
Diabetes duration, years, mean (SD) | 15.95 (7.89) | 16.49 (7.66) | 15.39 (8.12) | 1.36 (0.91) | 16.13 (7.89) | 15.69 (7.89) | −0.54 (0.70) |
Insulin delivery by pump, n (%) | 144 (37) | 90 (45) | 54 (29) | 3.24 (<0.01) | 94 (41) | 50 (32) | −1.60 (0.11) |
First trimester HbA1c, mmol/mol, mean (SD) | 56.6 (9.9) | 57.1 (7.8) | 55.7 (12.4) | 1.30 (0.19) | 56.9 (9.9) | 56.1 (9.9) | −0.71 (0.48) |
First trimester HbA1c, %, mean (SD) | 7.3 (1.6) | 7.4 (1.4) | 7.2 (1.9) | 1.30 (0.19) | 7.4 (1.6) | 7.3 (1.6) | −0.71 (0.48) |
BMI, kg/m2, mean (SD) | 25.8 (4.6) | 25.7 (4.6) | 25.9 (4.7) | −0.34 (0.73) | 25.9 (4.7) | 25.4 (4.4) | −0.33 (0.74) |
Primiparous, n (%) | 187 (48) | 98 (49) | 89 (48) | 0.22 (0.82) | 66 (28) | 121 (78) | 0.08 (0.93 |
Gestation birth, weeks, mean (SD) | 37.2 (1.9) | 36.9 (1.7) | 37.5 (2.0) | −3.18 (<0.01) | 37.0 (1.6) | 37.3 (2.2) | −1.55 (0.12) |
Preterm delivery <37 weeks, n (%) | 132 (34) | 80 (40) | 52 (28) | 2.49 (0.01) | 83 (36) | 49 (32) | −0.80 (0.42) |
Caesarean section, n (%) | 224 (58) | 137 (69) | 87 (47) | 4.32 (<0.01) | 150 (65) | 74 (48) | −3.24 (<0.01) |
Birth weight, kg, mean (SD) | 3.69 (0.72) | 3.56 (0.71) | 3.82 (0.72) | 3.47 (<0.01) | 4.00 (0.55) | 3.00 (0.57) | −12.94 (<0.01) |
Birth weight percentile, mean (SD)* | 82.7 (24.7) | 82.0 (25.8) | 83.6 (23.4) | −0.64 (0.52) | 98.1 (2.67) | 59.6 (25.0) | −23.22 (<0.01) |
LGA ≥90th percentile, n (%) | 232 (60) | 122 (61) | 110 (59) | −1.17 (0.24) | 225 (97) | 7 (26) | −14.73 (<0.01) |
Results are given as n (%) or mean (SD). t test used where mean (SD) are given (t), and percentage used a two-sample test of proportion (z).
Birth weight was adjusted for infant sex and gestational age, maternal height, weight, parity, and ethnicity for singleton pregnancies using the Gestation Related Optimal Weight centile tool (15).