Characteristic . | Control patients without diabetes . | Patients with T1D . | Patients with T2D . | P value . |
---|---|---|---|---|
(n = 204) . | (n = 399) . | (n = 191) . | ||
Female sex | 102 (50) | 206 (48) | 64 (32) | <0.001 |
Baseline age (year) | 37.61 ± 19.79 | 39.90 ± 18.73 | 60.39 ± 8.16 | <0.001 |
BMI (kg/m2) | 23.78 ± 5.22 | 25.66 ± 4.91 | 31.38 ± 5.99 | <0.001 |
HbA1c (%) | 5.48 ± 0.35 | 8.25 ± 1.56 | 7.48 ± 1.34 | <0.001 |
CNFL (mm/mm2) | 16.48 ± 4.03 | 13.48 ± 4.29 | 13.80 ± 4.41 | <0.001 |
CNBD (branches/mm2) | 35.36 ± 19.63 | 22.66 ± 16.74 | 26.95 ± 19.98 | <0.001 |
CNFD (fibers/mm2) | 27.29 ± 9.03 | 20.55 ± 8.98 | 20.54 ± 9.48 | <0.001 |
CNFL slope (percent/year) | 0.64 ± 9.30 | −0.82 ± 5.05 | −0.25 ± 4.47 | 0.138 |
CNFL slope 90% CI | −5.9 to 5.0 | −14.0 to 9.9 | −14.1 to 14.3 | — |
RCNFL (+) | 11 (5.4) | 64 (16.0) | 37 (19.4)* | 0.001 |
Median follow-up time (years) | 3.0 (2, 3.8) | 4.4 (4.0, 7.0) | 5.3 (3.0, 6.0) | <0.001 |
Characteristic . | Control patients without diabetes . | Patients with T1D . | Patients with T2D . | P value . |
---|---|---|---|---|
(n = 204) . | (n = 399) . | (n = 191) . | ||
Female sex | 102 (50) | 206 (48) | 64 (32) | <0.001 |
Baseline age (year) | 37.61 ± 19.79 | 39.90 ± 18.73 | 60.39 ± 8.16 | <0.001 |
BMI (kg/m2) | 23.78 ± 5.22 | 25.66 ± 4.91 | 31.38 ± 5.99 | <0.001 |
HbA1c (%) | 5.48 ± 0.35 | 8.25 ± 1.56 | 7.48 ± 1.34 | <0.001 |
CNFL (mm/mm2) | 16.48 ± 4.03 | 13.48 ± 4.29 | 13.80 ± 4.41 | <0.001 |
CNBD (branches/mm2) | 35.36 ± 19.63 | 22.66 ± 16.74 | 26.95 ± 19.98 | <0.001 |
CNFD (fibers/mm2) | 27.29 ± 9.03 | 20.55 ± 8.98 | 20.54 ± 9.48 | <0.001 |
CNFL slope (percent/year) | 0.64 ± 9.30 | −0.82 ± 5.05 | −0.25 ± 4.47 | 0.138 |
CNFL slope 90% CI | −5.9 to 5.0 | −14.0 to 9.9 | −14.1 to 14.3 | — |
RCNFL (+) | 11 (5.4) | 64 (16.0) | 37 (19.4)* | 0.001 |
Median follow-up time (years) | 3.0 (2, 3.8) | 4.4 (4.0, 7.0) | 5.3 (3.0, 6.0) | <0.001 |
Data are presented as mean ± SD, n (%), or median (interquartile range). P value for trend comparison between control patients without diabetes and the T1D and T2D subcohorts.
The combined number of patients with T1D and with T2D who had RCNFL was 101, providing a prevalence of 17.1% (101/590).