Relations between median MBF at rest and during stress, measurements of cardiac structure and function, and selected medications in patients with type 2 diabetes
| . | MBF at rest . | MBF during stress . | ||
|---|---|---|---|---|
| Below the median (n = 97) . | Above the median (n = 96) . | Below the median (n = 97) . | Above the median (n = 96) . | |
| LVEF (%) | 61 ± 7 | 62 ± 7 | 62 ± 9 | 63 ± 6 |
| EDV (mL) | 156 ± 34 | 152 ± 38 | 158 ± 38 | 150 ± 34 |
| EDV index (mL/m2) | 72 ± 14 | 72 ± 16 | 73 ± 16 | 71 ± 13 |
| ESV (mL) | 63 ± 24 | 62 ± 22 | 62 ± 27 | 56 ± 18 |
| ESV index (mL/m2) | 29 ± 10 | 28 ± 9 | 29 ± 12 | 26 ± 18 |
| SV (mL) | 94 ± 19 | 97 ± 22 | 95 ± 20 | 95 ± 21 |
| LV mass (g) | 143 ± 38 | 138 ± 37 | 149 ± 40 | 126 ± 32* |
| LV mass index (g/m2) | 65 ± 13 | 63 ± 15 | 68 ± 15 | 59 ± 11* |
| LA volume (mL) | 98 ± 25 | 94 ± 25 | 101 ± 25 | 91 ± 24* |
| LA volume index (mL/m2) | 45 ± 11 | 44 ± 11 | 47 ± 11 | 43 ± 9* |
| Ischemic LGE | 8 | 9 | 10 | 7 |
| Mean E/e* | 7.7 ± 2.9 | 7.9 ± 2.6 | 8.4 ± 2.9 | 7.1 ± 2.5* |
| ECV (%) | 29.1 ± 3.3 | 28.7 ± 3.2 | 30.7 ± 3.4 | 27.2 ± 2.1* |
| Medication | ||||
| SGLT-2 inhibitors | 40 | 28† | 35 | 33 |
| GLP-1 analogs | 41 | 35 | 42 | 34 |
| Insulin | 57 | 59 | 62 | 54 |
| . | MBF at rest . | MBF during stress . | ||
|---|---|---|---|---|
| Below the median (n = 97) . | Above the median (n = 96) . | Below the median (n = 97) . | Above the median (n = 96) . | |
| LVEF (%) | 61 ± 7 | 62 ± 7 | 62 ± 9 | 63 ± 6 |
| EDV (mL) | 156 ± 34 | 152 ± 38 | 158 ± 38 | 150 ± 34 |
| EDV index (mL/m2) | 72 ± 14 | 72 ± 16 | 73 ± 16 | 71 ± 13 |
| ESV (mL) | 63 ± 24 | 62 ± 22 | 62 ± 27 | 56 ± 18 |
| ESV index (mL/m2) | 29 ± 10 | 28 ± 9 | 29 ± 12 | 26 ± 18 |
| SV (mL) | 94 ± 19 | 97 ± 22 | 95 ± 20 | 95 ± 21 |
| LV mass (g) | 143 ± 38 | 138 ± 37 | 149 ± 40 | 126 ± 32* |
| LV mass index (g/m2) | 65 ± 13 | 63 ± 15 | 68 ± 15 | 59 ± 11* |
| LA volume (mL) | 98 ± 25 | 94 ± 25 | 101 ± 25 | 91 ± 24* |
| LA volume index (mL/m2) | 45 ± 11 | 44 ± 11 | 47 ± 11 | 43 ± 9* |
| Ischemic LGE | 8 | 9 | 10 | 7 |
| Mean E/e* | 7.7 ± 2.9 | 7.9 ± 2.6 | 8.4 ± 2.9 | 7.1 ± 2.5* |
| ECV (%) | 29.1 ± 3.3 | 28.7 ± 3.2 | 30.7 ± 3.4 | 27.2 ± 2.1* |
| Medication | ||||
| SGLT-2 inhibitors | 40 | 28† | 35 | 33 |
| GLP-1 analogs | 41 | 35 | 42 | 34 |
| Insulin | 57 | 59 | 62 | 54 |
Values are presented as mean ± SD or n. GLP-1, glucagon-like peptide 1; LVEF, left ventricular ejection fraction.
P < 0.05 vs. MBF below the median.
P = 0.06 vs. MBF below the median.