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TABLE 2

Bolus Insulins Available in the United States (28,29,31,32)

Generic NameTrade NameFormConcentrationOnset, minutesPeak, minutesDuration, hoursCost (WAC) (29)
Ultra-rapid-acting insulins 
Faster aspart Fiasp Analog U-100 16–20 63 5–7 $289.36/one 10-mL vial 
$558.83/five 3-mL FlexPens 
$537.47/five 3-mL Penfill cartridges 
URLi Lyumjev Analog U-100    $274.70/one 10-mL vial 
       $530.40/five 3-mL KwikPens 
   U-200 15–17 57 4.6–7.3 $424.32/two 3-mL KwikPens 
Rapid-acting insulins 
Insulin aspart Novolog Analog U-100 10–20 30–90 3–5 $289.36/one 10-mL vial 
$537.45/five 3-mL Penfill cartridges 
$558.83/five 3-mL FlexPens 
Insulin glulisine Apidra Analog U-100 10–20 30–90 3–5 $283.95/one 10-mL vial 
$548.52/five 3-mL SoloStar pens 
Insulin lispro Humalog Analog U-100 10–20 30–90 3–5 $137.35/one 10-mL vial 
$265.20/five 3-mL KwikPens or KwikPen Juniors 
U-200 15 30–90 3–5 $424.32/two 3-mL KwikPens 
Insulin lispro, biosimilar Admelog Analog U-100 15 30–90 3–5 $130.76/one 10-mL vial 
$39.23/one 3-mL vial 
$252.47/five 3-mL SoloStar pens 
Insulin, inhaled Afrezza Human U-100 12 35–55 1.5–4.5 $353.91/90 4-unit cartridges 
$707.82/90 8-unit cartridges 
$1,061.74/90 12-unit cartridges 
Short-acting insulins 
Insulin, regular Humulin R Human U-100 30–60 120–240 5–8 $148.70/one 10-mL vial 
$44.61/one 3-mL vial 
Novolin R Human U-100 30 80–120 Up to 8 $137.70/one 10-mL vial 
$25/one 10-mL vial (ReliOn) (29) 
Generic NameTrade NameFormConcentrationOnset, minutesPeak, minutesDuration, hoursCost (WAC) (29)
Ultra-rapid-acting insulins 
Faster aspart Fiasp Analog U-100 16–20 63 5–7 $289.36/one 10-mL vial 
$558.83/five 3-mL FlexPens 
$537.47/five 3-mL Penfill cartridges 
URLi Lyumjev Analog U-100    $274.70/one 10-mL vial 
       $530.40/five 3-mL KwikPens 
   U-200 15–17 57 4.6–7.3 $424.32/two 3-mL KwikPens 
Rapid-acting insulins 
Insulin aspart Novolog Analog U-100 10–20 30–90 3–5 $289.36/one 10-mL vial 
$537.45/five 3-mL Penfill cartridges 
$558.83/five 3-mL FlexPens 
Insulin glulisine Apidra Analog U-100 10–20 30–90 3–5 $283.95/one 10-mL vial 
$548.52/five 3-mL SoloStar pens 
Insulin lispro Humalog Analog U-100 10–20 30–90 3–5 $137.35/one 10-mL vial 
$265.20/five 3-mL KwikPens or KwikPen Juniors 
U-200 15 30–90 3–5 $424.32/two 3-mL KwikPens 
Insulin lispro, biosimilar Admelog Analog U-100 15 30–90 3–5 $130.76/one 10-mL vial 
$39.23/one 3-mL vial 
$252.47/five 3-mL SoloStar pens 
Insulin, inhaled Afrezza Human U-100 12 35–55 1.5–4.5 $353.91/90 4-unit cartridges 
$707.82/90 8-unit cartridges 
$1,061.74/90 12-unit cartridges 
Short-acting insulins 
Insulin, regular Humulin R Human U-100 30–60 120–240 5–8 $148.70/one 10-mL vial 
$44.61/one 3-mL vial 
Novolin R Human U-100 30 80–120 Up to 8 $137.70/one 10-mL vial 
$25/one 10-mL vial (ReliOn) (29) 

WAC, wholesale acquisition cost.

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