Parent factors . | Youth factors . | |||||||
---|---|---|---|---|---|---|---|---|
Baseline . | During study** . | |||||||
BMI z . | HbA1c (%) . | HbA1c (mmol/mol) . | Hypertension (%) . | Medication adherence ≥80% (%) . | SAE(s) reported (%) . | Hypertension (%) . | Loss of glycemic control (%) . | |
BMI >30 kg/m2 | ||||||||
No | 2.04 ± 0.47 | 6.0 ± 0.7 | 42 ± 8 | 13.7 | 60.7 | 12.9 | 25.0 | 36.3 |
Yes | 2.29 ± 0.40 | 6.0 ± 0.8 | 42 ± 9 | 14.0 | 59.3 | 22.4 | 33.2 | 46.7 |
P value | <0.0001 | 0.6502 | 0.6502 | 0.9369 | 0.8109 | 0.0275 | 0.1115 | 0.0606 |
Diabetes | ||||||||
No | 2.23 ± 0.46 | 5.9 ± 0.7 | 41 ± 8 | 14.8 | 53.4 | 18.9 | 32.5 | 38.2 |
Yes | 2.24 ± 0.47 | 6.2 ± 0.8 | 44 ± 9 | 21.8 | 60.9 | 23.4 | 32.6 | 53.6 |
P value | 0.7910 | <0.0001 | <0.0001 | 0.0262 | 0.0724 | 0.1863 | 0.9953 | 0.0002 |
SAE reported | ||||||||
None | 2.21 ± 0.47 | 6.0 ± 0.8 | 42 ± 9 | 16.3 | 57.4 | 20.4 | 31.7 | 43.0 |
≥1 | 2.32 ± 0.45 | 6.1 ± 0.8 | 43 ± 9 | 25.5 | 55.6 | 27.5 | 37.3 | 57.8 |
P value | 0.0317 | 0.1647 | 0.1647 | 0.0330 | 0.7412 | 0.1188 | 0.2754 | 0.0060 |
Hypertension | ||||||||
No | 2.19 ± 0.47 | 5.9 ± 0.7 | 41 ± 8 | 13.1 | 59.1 | 19.6 | 27.4 | 46.9 |
Yes | 2.30 ± 0.45 | 6.2 ± 0.8 | 44 ± 9 | 24.9 | 53.5 | 22.9 | 40.4 | 42.9 |
P value | 0.0038 | 0.0004 | 0.0004 | 0.0002 | 0.1899 | 0.3286 | 0.0008 | 0.3237 |
Depressive symptoms | ||||||||
No | 2.23 ± 0.46 | 6.0 ± 0.7 | 42 ± 8 | 18.1 | 57.5 | 19.2 | 33.4 | 44.5 |
Yes | 2.22 ± 0.48 | 6.1 ± 0.7 | 43 ± 8 | 16.7 | 55.9 | 27.0 | 29.4 | 49.2 |
P value | 0.8328 | 0.1252 | 0.1252 | 0.6976 | 0.7566 | 0.0601 | 0.3858 | 0.3489 |
Subclinical BE† | ||||||||
No | 2.22 ± 0.48 | 6.0 ± 0.8 | 42 ± 9 | 17.9 | 56.5 | 21.4 | 33.0 | 45.3 |
Yes | 2.29 ± 0.35 | 6.1 ± 0.8 | 43 ± 9 | 16.7 | 65.6 | 24.2 | 28.8 | 51.5 |
P value | 0.2700 | 0.6707 | 0.6707 | 0.8087 | 0.1574 | 0.5963 | 0.4899 | 0.3399 |
Clinical BE | ||||||||
No | 2.23 ± 0.46 | 6.0 ± 0.8 | 42 ± 9 | 17.9 | 58.2 | 21.3 | 32.8 | 46.5 |
Yes | 2.25 ± 0.54 | 6.2 ± 0.8 | 44 ± 9 | 15.6 | 43.3 | 28.1 | 28.1 | 37.5 |
P value | 0.7898 | 0.1893 | 0.1893 | 0.7445 | 0.1103 | 0.3773 | 0.5817 | 0.3196 |
Household annual income | ||||||||
<$25,000 | 2.24 ± 0.46 | 6.0 ± 0.8 | 42 ± 9 | 21.1 | 53.4 | 26.8 | 33.3 | 46.9 |
$25,000–$49,999 | 2.24 ± 0.47 | 6.0 ± 0.8 | 42 ± 9 | 13.1 | 58.8 | 21.5 | 31.9 | 47.1 |
≥$50,000 | 2.20 ± 0.47 | 6.0 ± 0.7 | 42 ± 8 | 21.2 | 64.2 | 17.1 | 32.9 | 37.0 |
P value | 0.6917 | 0.5084 | 0.5084 | 0.0582 | 0.1292 | 0.0834 | 0.9542 | 0.1075 |
Parent factors . | Youth factors . | |||||||
---|---|---|---|---|---|---|---|---|
Baseline . | During study** . | |||||||
BMI z . | HbA1c (%) . | HbA1c (mmol/mol) . | Hypertension (%) . | Medication adherence ≥80% (%) . | SAE(s) reported (%) . | Hypertension (%) . | Loss of glycemic control (%) . | |
BMI >30 kg/m2 | ||||||||
No | 2.04 ± 0.47 | 6.0 ± 0.7 | 42 ± 8 | 13.7 | 60.7 | 12.9 | 25.0 | 36.3 |
Yes | 2.29 ± 0.40 | 6.0 ± 0.8 | 42 ± 9 | 14.0 | 59.3 | 22.4 | 33.2 | 46.7 |
P value | <0.0001 | 0.6502 | 0.6502 | 0.9369 | 0.8109 | 0.0275 | 0.1115 | 0.0606 |
Diabetes | ||||||||
No | 2.23 ± 0.46 | 5.9 ± 0.7 | 41 ± 8 | 14.8 | 53.4 | 18.9 | 32.5 | 38.2 |
Yes | 2.24 ± 0.47 | 6.2 ± 0.8 | 44 ± 9 | 21.8 | 60.9 | 23.4 | 32.6 | 53.6 |
P value | 0.7910 | <0.0001 | <0.0001 | 0.0262 | 0.0724 | 0.1863 | 0.9953 | 0.0002 |
SAE reported | ||||||||
None | 2.21 ± 0.47 | 6.0 ± 0.8 | 42 ± 9 | 16.3 | 57.4 | 20.4 | 31.7 | 43.0 |
≥1 | 2.32 ± 0.45 | 6.1 ± 0.8 | 43 ± 9 | 25.5 | 55.6 | 27.5 | 37.3 | 57.8 |
P value | 0.0317 | 0.1647 | 0.1647 | 0.0330 | 0.7412 | 0.1188 | 0.2754 | 0.0060 |
Hypertension | ||||||||
No | 2.19 ± 0.47 | 5.9 ± 0.7 | 41 ± 8 | 13.1 | 59.1 | 19.6 | 27.4 | 46.9 |
Yes | 2.30 ± 0.45 | 6.2 ± 0.8 | 44 ± 9 | 24.9 | 53.5 | 22.9 | 40.4 | 42.9 |
P value | 0.0038 | 0.0004 | 0.0004 | 0.0002 | 0.1899 | 0.3286 | 0.0008 | 0.3237 |
Depressive symptoms | ||||||||
No | 2.23 ± 0.46 | 6.0 ± 0.7 | 42 ± 8 | 18.1 | 57.5 | 19.2 | 33.4 | 44.5 |
Yes | 2.22 ± 0.48 | 6.1 ± 0.7 | 43 ± 8 | 16.7 | 55.9 | 27.0 | 29.4 | 49.2 |
P value | 0.8328 | 0.1252 | 0.1252 | 0.6976 | 0.7566 | 0.0601 | 0.3858 | 0.3489 |
Subclinical BE† | ||||||||
No | 2.22 ± 0.48 | 6.0 ± 0.8 | 42 ± 9 | 17.9 | 56.5 | 21.4 | 33.0 | 45.3 |
Yes | 2.29 ± 0.35 | 6.1 ± 0.8 | 43 ± 9 | 16.7 | 65.6 | 24.2 | 28.8 | 51.5 |
P value | 0.2700 | 0.6707 | 0.6707 | 0.8087 | 0.1574 | 0.5963 | 0.4899 | 0.3399 |
Clinical BE | ||||||||
No | 2.23 ± 0.46 | 6.0 ± 0.8 | 42 ± 9 | 17.9 | 58.2 | 21.3 | 32.8 | 46.5 |
Yes | 2.25 ± 0.54 | 6.2 ± 0.8 | 44 ± 9 | 15.6 | 43.3 | 28.1 | 28.1 | 37.5 |
P value | 0.7898 | 0.1893 | 0.1893 | 0.7445 | 0.1103 | 0.3773 | 0.5817 | 0.3196 |
Household annual income | ||||||||
<$25,000 | 2.24 ± 0.46 | 6.0 ± 0.8 | 42 ± 9 | 21.1 | 53.4 | 26.8 | 33.3 | 46.9 |
$25,000–$49,999 | 2.24 ± 0.47 | 6.0 ± 0.8 | 42 ± 9 | 13.1 | 58.8 | 21.5 | 31.9 | 47.1 |
≥$50,000 | 2.20 ± 0.47 | 6.0 ± 0.7 | 42 ± 8 | 21.2 | 64.2 | 17.1 | 32.9 | 37.0 |
P value | 0.6917 | 0.5084 | 0.5084 | 0.0582 | 0.1292 | 0.0834 | 0.9542 | 0.1075 |
*Mean ± SD or % of the factor in the youth are shown in the table by the status of a factor in the parent. The P values are from unadjusted models testing for an association between the parental factor and the youth factor (P < 0.05 in bold).
**Youth factors during the study include baseline data.
†Clinical BE (≥4 episodes) was excluded from the comparison group of normal plus overeaters vs. subclinical BE (1–3 episodes).