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Table 2

Measured A1C, glycemic, and insulin parameter changes, baseline to end of study

FAS
Per protocol
PRTCSIIPRTCSII
n 46 54 30 53 
Δ Blood glucose (mg/dl) −30.6 ± 54.0* −10.8 ± 39.6 −39.6 ± 55.8* −9.0 ± 39.6 
Δ Hyperglycemia >190 mg/dl (h/day) −3.5 ± 4.8* −0.7 ± 3.8 −4.1 ± 5.1* −0.6 ± 3.8 
Δ Hyperglycemia AUC (mg · dl−1 · day−1−17.1 ± 31.7 −5.8 ± 26.7 −19.1 ± 35.5 −5.2 ± 26.5 
Δ Hyperglycemia (episodes/day) −0.2 ± 0.7 −0.2 ± 0.7 −0.2 ± 0.7 −0.2 ± 0.7 
Δ Hypoglycemia <70 mg/dl (h/day) 0.3 ± 1.4 0 ± 1.2 0.6 ± 1.3 0.0 ± 1.2 
Δ Hypoglycemia AUC (mg · dl−1 · day−10.4 ± 1.3 0.0 ± 1.8 0.7 ± 1.3 0.0 ± 1.8 
Δ Hypoglycemia (episodes/day) 0.1 ± 0.9 0.1 ± 0.7 0.2 ± 1.0 0.1 ± 0.7 
Δ MAGE (mg/dl) −27.5* −16.2 −20.4 −16.2 
Δ SD −15.8* −5.7 −11.3 −5.7 
Δ Daily insulin doses (units/day) 6.8 ± 17.3 1.5 ± 9.1 6.2 ± 14.8 1.1 ± 8.4 
Bolus insulin (%/day) 53.8 ± 10.0 49.8 ± 15.8 53.3 ± 9.3 49.7 ± 15.9 
Number of boluses/day 4.7 ± 1.4 3.9 ± 1.4 4.9 ± 1.4 3.9 ± 1.4 
FAS
Per protocol
PRTCSIIPRTCSII
n 46 54 30 53 
Δ Blood glucose (mg/dl) −30.6 ± 54.0* −10.8 ± 39.6 −39.6 ± 55.8* −9.0 ± 39.6 
Δ Hyperglycemia >190 mg/dl (h/day) −3.5 ± 4.8* −0.7 ± 3.8 −4.1 ± 5.1* −0.6 ± 3.8 
Δ Hyperglycemia AUC (mg · dl−1 · day−1−17.1 ± 31.7 −5.8 ± 26.7 −19.1 ± 35.5 −5.2 ± 26.5 
Δ Hyperglycemia (episodes/day) −0.2 ± 0.7 −0.2 ± 0.7 −0.2 ± 0.7 −0.2 ± 0.7 
Δ Hypoglycemia <70 mg/dl (h/day) 0.3 ± 1.4 0 ± 1.2 0.6 ± 1.3 0.0 ± 1.2 
Δ Hypoglycemia AUC (mg · dl−1 · day−10.4 ± 1.3 0.0 ± 1.8 0.7 ± 1.3 0.0 ± 1.8 
Δ Hypoglycemia (episodes/day) 0.1 ± 0.9 0.1 ± 0.7 0.2 ± 1.0 0.1 ± 0.7 
Δ MAGE (mg/dl) −27.5* −16.2 −20.4 −16.2 
Δ SD −15.8* −5.7 −11.3 −5.7 
Δ Daily insulin doses (units/day) 6.8 ± 17.3 1.5 ± 9.1 6.2 ± 14.8 1.1 ± 8.4 
Bolus insulin (%/day) 53.8 ± 10.0 49.8 ± 15.8 53.3 ± 9.3 49.7 ± 15.9 
Number of boluses/day 4.7 ± 1.4 3.9 ± 1.4 4.9 ± 1.4 3.9 ± 1.4 

Data are means ± SD or means.

*P ≤ 0.005 vs. CSII group.

P ≤ 0.05 vs. CSII group.

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