. | Nonprogressors . | Progressors . | P . |
---|---|---|---|
Fasting plasma glucose (mmol/l) | 4.92 ± 0.05 | 5.27 ± 0.11 | 0.002 |
2-h glucose (mmol/l) | 6.2 ± 0.12 | 6.5 ± 0.28 | 0.27 |
Fasting insulin (pmol/l) | 183.0 (130.5–229.5) | 195.0 (138.0–229.5) | 0.89 |
Proinsulin (pmol/l) | 20 (14.0–32.0) | 22 (13.0–25.5) | 0.56 |
A1C (%) | 5.3 ± 0.3 | 5.5 ± 0.3 | 0.049 |
SI | 3.8 (1.99–9.05) | 4.5 (2.1–4.5) | 0.82 |
β-Cell responsivity (Φ) | |||
Φs | 68.9 (52.9–85.5) | 62.5 (48.8–89.1) | 0.95 |
Φd | 2,514.7 (1,488.6–3,618.8) | 2,001.6 (1,295.0–2,276.4) | 0.04 |
Φtot | 106.7 (79.1–139.8) | 87.9 (77.8–119.8) | 0.35 |
DI | 612.5 (406.2–1,348.1) | 545.8 (368.7–1,147.7) | 0.66 |
Adipokines | |||
Leptin (ng/ml) | 25 (17.0–41.0) | 31 (28.3–43.8) | 0.02 |
Adiponectin (μg/ml) | 6.8 (4.0–9.6) | 6.9 (5.6–8.8) | 0.43 |
IL-6 (pg/ml) | 1.89 (1.1–3.1) | 3.1 (1.5–4.5) | 0.21 |
Lipids | |||
HDL cholesterol (mmol/l) | 1.05 (0.83–1.18) | 1.03 (0.83–1.22) | 0.96 |
Triglycerides (mmol/l) | 1.03 (0.77–1.7) | 1.13 (0.80–1.39) | 0.76 |
. | Nonprogressors . | Progressors . | P . |
---|---|---|---|
Fasting plasma glucose (mmol/l) | 4.92 ± 0.05 | 5.27 ± 0.11 | 0.002 |
2-h glucose (mmol/l) | 6.2 ± 0.12 | 6.5 ± 0.28 | 0.27 |
Fasting insulin (pmol/l) | 183.0 (130.5–229.5) | 195.0 (138.0–229.5) | 0.89 |
Proinsulin (pmol/l) | 20 (14.0–32.0) | 22 (13.0–25.5) | 0.56 |
A1C (%) | 5.3 ± 0.3 | 5.5 ± 0.3 | 0.049 |
SI | 3.8 (1.99–9.05) | 4.5 (2.1–4.5) | 0.82 |
β-Cell responsivity (Φ) | |||
Φs | 68.9 (52.9–85.5) | 62.5 (48.8–89.1) | 0.95 |
Φd | 2,514.7 (1,488.6–3,618.8) | 2,001.6 (1,295.0–2,276.4) | 0.04 |
Φtot | 106.7 (79.1–139.8) | 87.9 (77.8–119.8) | 0.35 |
DI | 612.5 (406.2–1,348.1) | 545.8 (368.7–1,147.7) | 0.66 |
Adipokines | |||
Leptin (ng/ml) | 25 (17.0–41.0) | 31 (28.3–43.8) | 0.02 |
Adiponectin (μg/ml) | 6.8 (4.0–9.6) | 6.9 (5.6–8.8) | 0.43 |
IL-6 (pg/ml) | 1.89 (1.1–3.1) | 3.1 (1.5–4.5) | 0.21 |
Lipids | |||
HDL cholesterol (mmol/l) | 1.05 (0.83–1.18) | 1.03 (0.83–1.22) | 0.96 |
Triglycerides (mmol/l) | 1.03 (0.77–1.7) | 1.13 (0.80–1.39) | 0.76 |
Data are means ± SD or median (interquartile range).