Incident cases of type 1 diabetes by HLA DRB1 genotype
| . | 1985 . | . | 2002 . | . | ||
|---|---|---|---|---|---|---|
| . | Incidence 11.3/100,000 person-years* . | . | Incidence 23.2/100,000 person-years . | . | ||
| DRB1 genotype | Proportion | Cases† | Proportion | Cases | ||
| DR3,4 | 47% | 5.3 | 28% | 6.5 | ||
| DR3,3 and DR4,4 | 12% | 1.4 | 21% | 4.9 | ||
| DR3,X and DR4,X‡ | 39% | 4.4 | 48% | 11.1 | ||
| DRX,X | 1% | 0.1 | 3% | 0.7 | ||
| . | 1985 . | . | 2002 . | . | ||
|---|---|---|---|---|---|---|
| . | Incidence 11.3/100,000 person-years* . | . | Incidence 23.2/100,000 person-years . | . | ||
| DRB1 genotype | Proportion | Cases† | Proportion | Cases | ||
| DR3,4 | 47% | 5.3 | 28% | 6.5 | ||
| DR3,3 and DR4,4 | 12% | 1.4 | 21% | 4.9 | ||
| DR3,X and DR4,X‡ | 39% | 4.4 | 48% | 11.1 | ||
| DRX,X | 1% | 0.1 | 3% | 0.7 | ||
Based on ref. 14.
Calculated as incidence times proportion DRB1 genotype.
Where X is non-3 or non-4 DRB1 allele.