. | M . | Albuminuria (n = 265) . | Macroalbuminuria (n = 47) . | eGFR <60 mL/min/1.73 m2 (n = 173) . | eGFR <45 mL/min/1.73 m2 (n = 64) . |
---|---|---|---|---|---|
Ln MGO | 1 | 1.52 (1.31–1.76) | 2.05 (1.60–2.62) | 2.56 (2.08–3.14) | 5.41 (3.55–8.24) |
2 | 1.48 (1.26–1.72) | 2.05 (1.58–2.66) | 2.77 (2.21–3.47) | 6.10 (4.08–9.12) | |
3 | 1.29 (1.08–1.53) | 1.36 (0.99–1.87) | — | — | |
Ln GO | 1 | 1.37 (1.17–1.60) | 1.72 (1.25–2.38) | 1.53 (1.26–1.86) | 2.70 (1.98–3.68) |
2 | 1.31 (1.00–1.54) | 1.62 (1.13–2.32) | 1.59 (1.29–1.96) | 3.11 (2.19–4.41) | |
3 | 1.21 (1.02–1.43) | 1.18 (0.82–1.69) | — | — | |
Ln 3-DG | 1 | 1.25 (1.08–1.44) | 1.35 (1.01–1.81) | 0.92 (0.77–1.09) | 1.10 (0.84–1.42) |
2 | 1.10 (0.92–1.31) | 1.21 (0.84–1.74) | 0.97 (0.78–1.19) | 1.25 (0.91–1.73) | |
3 | 1.12 (0.94–1.34) | 1.22 (0.84–1.79) | — | — | |
Dicarbonyl score | 1 | 1.48 (1.24–1.76) | 1.97 (1.48–2.62) | 1.62 (1.36–1.94) | 2.83 (2.15–3.74) |
2 | 1.39 (1.07–1.65) | 2.00 (1.42–2.82) | 1.87 (1.52–2.30) | 4.01 (2.81–5.73) | |
3 | 1.27 (1.07–1.51) | 1.33 (0.93–1.92) | — | — |
. | M . | Albuminuria (n = 265) . | Macroalbuminuria (n = 47) . | eGFR <60 mL/min/1.73 m2 (n = 173) . | eGFR <45 mL/min/1.73 m2 (n = 64) . |
---|---|---|---|---|---|
Ln MGO | 1 | 1.52 (1.31–1.76) | 2.05 (1.60–2.62) | 2.56 (2.08–3.14) | 5.41 (3.55–8.24) |
2 | 1.48 (1.26–1.72) | 2.05 (1.58–2.66) | 2.77 (2.21–3.47) | 6.10 (4.08–9.12) | |
3 | 1.29 (1.08–1.53) | 1.36 (0.99–1.87) | — | — | |
Ln GO | 1 | 1.37 (1.17–1.60) | 1.72 (1.25–2.38) | 1.53 (1.26–1.86) | 2.70 (1.98–3.68) |
2 | 1.31 (1.00–1.54) | 1.62 (1.13–2.32) | 1.59 (1.29–1.96) | 3.11 (2.19–4.41) | |
3 | 1.21 (1.02–1.43) | 1.18 (0.82–1.69) | — | — | |
Ln 3-DG | 1 | 1.25 (1.08–1.44) | 1.35 (1.01–1.81) | 0.92 (0.77–1.09) | 1.10 (0.84–1.42) |
2 | 1.10 (0.92–1.31) | 1.21 (0.84–1.74) | 0.97 (0.78–1.19) | 1.25 (0.91–1.73) | |
3 | 1.12 (0.94–1.34) | 1.22 (0.84–1.79) | — | — | |
Dicarbonyl score | 1 | 1.48 (1.24–1.76) | 1.97 (1.48–2.62) | 1.62 (1.36–1.94) | 2.83 (2.15–3.74) |
2 | 1.39 (1.07–1.65) | 2.00 (1.42–2.82) | 1.87 (1.52–2.30) | 4.01 (2.81–5.73) | |
3 | 1.27 (1.07–1.51) | 1.33 (0.93–1.92) | — | — |
Data were analyzed using logistic regression analyses. Odds ratio is expressed per SD increase of Ln-transformed plasma dicarbonyl. Model 1, adjusted for age and sex; model 2, model 1 adjustments plus adjustment for total cholesterol, BMI, current smoking and systolic blood pressure, prior CVD, HbA1c, and lipid-modifying and blood pressure– and glucose-lowering treatment; and model 3, model 2 adjustments plus adjustment for eGFR. M, model.