. | Age-adjusted HR (95% CI) . | HR (95% CI) adjusted for race and sex . | HR (95% CI) adjusted for race, sex, and baseline health conditions* . | HR (95% CI) adjusted for race, sex, baseline health conditions,* and frequency of HbA1c measurement . |
---|---|---|---|---|
% of HbA1c measurements <6% | ||||
<10 | ref | ref | ref | ref |
10 to <25 | 1.63 (0.88, 3.04) | 1.55 (0.83, 2.89) | 1.50 (0.80, 2.82) | 1.51 (0.80, 2.83) |
25 to <75 | 1.54 (0.85, 2.78) | 1.46 (0.80, 2.65) | 1.41 (0.77, 2.57) | 1.41 (0.77, 2.57) |
≥75 | 1.64 (0.72, 3.72) | 1.59 (0.70, 3.63) | 1.02 (0.43, 2.42) | 1.03 (0.43, 2.44) |
% of HbA1c measurements 6.0–6.9% | ||||
<10 | ref | ref | ref | ref |
10 to <25 | 0.83 (0.51, 1.34) | 0.82 (0.50, 1.32) | 0.85 (0.53, 1.38) | 0.86 (0.53, 1.39) |
25 to <75 | 0.66 (0.45, 0.96) | 0.65 (0.44, 0.95) | 0.66 (0.45, 0.98) | 0.66 (0.45, 0.98) |
≥75 | 0.41 (0.21, 0.81) | 0.39 (0.20, 0.79) | 0.42 (0.21, 0.83) | 0.42 (0.21, 0.83) |
% of HbA1c measurements 7.0–7.9% | ||||
<10 | ref | ref | ref | ref |
10 to <25 | 1.15 (0.73, 1.81) | 1.15 (0.73, 1.81) | 1.22 (0.77, 1.93) | 1.22 (0.77, 1.94) |
25 to <75 | 0.63 (0.44, 0.92) | 0.65 (0.45, 0.95) | 0.69 (0.48, 1.01) | 0.69 (0.48, 1.01) |
≥75 | 0.36 (0.17, 0.77) | 0.39 (0.18, 0.81) | 0.39 (0.19, 0.83) | 0.39 (0.18, 0.83) |
% of HbA1c measurements 8.0–8.9% | ||||
<10 | ref | ref | ref | ref |
10 to <25 | 1.67 (1.09, 2.57) | 1.67 (1.09, 2.58) | 1.77 (1.15, 2.73) | 1.78 (1.15, 2.74) |
25 to <75 | 1.50 (1.04, 2.18) | 1.49 (1.02, 2.16) | 1.54 (1.06, 2.25) | 1.55 (1.06, 2.26) |
≥75 | 2.37 (1.16, 4.82) | 2.32 (1.14, 4.72) | 2.48 (1.22, 5.07) | 2.51 (1.23, 5.11) |
% of HbA1c measurements ≥9% | ||||
<10 | ref | ref | ref | ref |
10 to <25 | 2.19 (1.40, 3.42) | 2.15 (1.37, 3.38) | 2.25 (1.43, 3.54) | 2.26 (1.44, 3.55) |
25 to <75 | 1.78 (1.16, 2.72) | 1.76 (1.15, 2.71) | 1.83 (1.19, 2.83) | 1.83 (1.19, 2.83) |
≥75 | 2.15 (1.17, 3.98) | 2.17 (1.17, 4.04) | 2.15 (1.14, 4.04) | 2.13 (1.13, 4.01) |
. | Age-adjusted HR (95% CI) . | HR (95% CI) adjusted for race and sex . | HR (95% CI) adjusted for race, sex, and baseline health conditions* . | HR (95% CI) adjusted for race, sex, baseline health conditions,* and frequency of HbA1c measurement . |
---|---|---|---|---|
% of HbA1c measurements <6% | ||||
<10 | ref | ref | ref | ref |
10 to <25 | 1.63 (0.88, 3.04) | 1.55 (0.83, 2.89) | 1.50 (0.80, 2.82) | 1.51 (0.80, 2.83) |
25 to <75 | 1.54 (0.85, 2.78) | 1.46 (0.80, 2.65) | 1.41 (0.77, 2.57) | 1.41 (0.77, 2.57) |
≥75 | 1.64 (0.72, 3.72) | 1.59 (0.70, 3.63) | 1.02 (0.43, 2.42) | 1.03 (0.43, 2.44) |
% of HbA1c measurements 6.0–6.9% | ||||
<10 | ref | ref | ref | ref |
10 to <25 | 0.83 (0.51, 1.34) | 0.82 (0.50, 1.32) | 0.85 (0.53, 1.38) | 0.86 (0.53, 1.39) |
25 to <75 | 0.66 (0.45, 0.96) | 0.65 (0.44, 0.95) | 0.66 (0.45, 0.98) | 0.66 (0.45, 0.98) |
≥75 | 0.41 (0.21, 0.81) | 0.39 (0.20, 0.79) | 0.42 (0.21, 0.83) | 0.42 (0.21, 0.83) |
% of HbA1c measurements 7.0–7.9% | ||||
<10 | ref | ref | ref | ref |
10 to <25 | 1.15 (0.73, 1.81) | 1.15 (0.73, 1.81) | 1.22 (0.77, 1.93) | 1.22 (0.77, 1.94) |
25 to <75 | 0.63 (0.44, 0.92) | 0.65 (0.45, 0.95) | 0.69 (0.48, 1.01) | 0.69 (0.48, 1.01) |
≥75 | 0.36 (0.17, 0.77) | 0.39 (0.18, 0.81) | 0.39 (0.19, 0.83) | 0.39 (0.18, 0.83) |
% of HbA1c measurements 8.0–8.9% | ||||
<10 | ref | ref | ref | ref |
10 to <25 | 1.67 (1.09, 2.57) | 1.67 (1.09, 2.58) | 1.77 (1.15, 2.73) | 1.78 (1.15, 2.74) |
25 to <75 | 1.50 (1.04, 2.18) | 1.49 (1.02, 2.16) | 1.54 (1.06, 2.25) | 1.55 (1.06, 2.26) |
≥75 | 2.37 (1.16, 4.82) | 2.32 (1.14, 4.72) | 2.48 (1.22, 5.07) | 2.51 (1.23, 5.11) |
% of HbA1c measurements ≥9% | ||||
<10 | ref | ref | ref | ref |
10 to <25 | 2.19 (1.40, 3.42) | 2.15 (1.37, 3.38) | 2.25 (1.43, 3.54) | 2.26 (1.44, 3.55) |
25 to <75 | 1.78 (1.16, 2.72) | 1.76 (1.15, 2.71) | 1.83 (1.19, 2.83) | 1.83 (1.19, 2.83) |
≥75 | 2.15 (1.17, 3.98) | 2.17 (1.17, 4.04) | 2.15 (1.14, 4.04) | 2.13 (1.13, 4.01) |
Estimates obtained from Cox proportional hazards models with age as time scale. ref, reference.
*Each of the following baseline health conditions was adjusted for in the model: history of stroke, myocardial infarction, nephropathy, neuropathy, severe diabetic retinopathy, peripheral arterial disease, hyperglycemic events, and hypoglycemic events.