Summary of study outcomes
| Metric . | OL . | Closed loop . | P level . |
|---|---|---|---|
| Primary outcomes: reduction in hypoglycemia | |||
| LBGI | 1.12 | 0.64 | 0.003 |
| Percentage of time below 3.9 mmol/L (70 mg/dL) | 1.25 | 0.70 | >0.1 |
| Number of hypoglycemic episodes/person/session requiring carbohydrate treatment | 2.39 | 1.22 | 0.021 |
| Grams of carbohydrate/person/session used for treatment of hypoglycemia | 39.7 | 17.6 | 0.022 |
| Secondary outcomes: glucose control | |||
| Percentage of time in the target range of 3.9–10 mmol/L (70–180 mg/dL) | 70.7 | 66.1 | >0.1 |
| Percentage of time above 180 mg/dL | 28.0 | 33.1 | >0.1 |
| Average BG | 8.45 mmol/L (152.1 mg/dL) | 8.96 mmol/L (161.3 mg/dL) | 0.042 |
| Glucose variability (SD) | 2.44 mmol/L (43.9 mg/dL) | 2.49 mmol/L (44.9 mg/dL) | >0.1 |
| Total meal carbohydrate content/person/session | 272.5 g | 266.2 g | >0.1 |
| Total insulin delivered/person/session | 62.6 units | 59.2 units | >0.1 |
| Metric . | OL . | Closed loop . | P level . |
|---|---|---|---|
| Primary outcomes: reduction in hypoglycemia | |||
| LBGI | 1.12 | 0.64 | 0.003 |
| Percentage of time below 3.9 mmol/L (70 mg/dL) | 1.25 | 0.70 | >0.1 |
| Number of hypoglycemic episodes/person/session requiring carbohydrate treatment | 2.39 | 1.22 | 0.021 |
| Grams of carbohydrate/person/session used for treatment of hypoglycemia | 39.7 | 17.6 | 0.022 |
| Secondary outcomes: glucose control | |||
| Percentage of time in the target range of 3.9–10 mmol/L (70–180 mg/dL) | 70.7 | 66.1 | >0.1 |
| Percentage of time above 180 mg/dL | 28.0 | 33.1 | >0.1 |
| Average BG | 8.45 mmol/L (152.1 mg/dL) | 8.96 mmol/L (161.3 mg/dL) | 0.042 |
| Glucose variability (SD) | 2.44 mmol/L (43.9 mg/dL) | 2.49 mmol/L (44.9 mg/dL) | >0.1 |
| Total meal carbohydrate content/person/session | 272.5 g | 266.2 g | >0.1 |
| Total insulin delivered/person/session | 62.6 units | 59.2 units | >0.1 |