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Journal Articles

In This Issue of Diabetes

Max Bingham, PhD

Diabetes 2023;72(10):1345–1346

https://doi.org/10.2337/db23-ti10

Published: 20 September 2023

View article titled, In This Issue of Diabetes

Journal Articles

Decoding the Mechanisms Behind Early Weaning–Driven Obesity and the Leucine “Solution”

M. Luisa Bonet, Joan Ribot, Catalina Picó

Diabetes 2023;72(10):1347–1349

https://doi.org/10.2337/dbi23-0011

Published: 20 September 2023

View article titled, Decoding the Mechanisms Behind Early Weaning–Driven Obesity and the Leucine “Solution”

Journal Articles

Treg-specific CD226 Deletion Reduces Diabetes Incidence in NOD Mice by Improving Regulatory T Cell Stability

Puchong Thirawatananond, Matthew E. Brown, Lindsey K. Sachs, Juan M. Arnoletti, Wen-I Yeh, Amanda L. Posgai, Melanie R. Shapiro, Yi-Guang Chen, Todd M. Brusko

Diabetes db230307

https://doi.org/10.2337/db23-0307

Published: 25 August 2023

View article titled, Treg-specific CD226 Deletion Reduces Diabetes Incidence in NOD Mice by Improving Regulatory T Cell Stability

Journal Articles

Obesity enables NLRP3 activation and induces myocardial fibrosis via hyperacetylation of HADHa

Yan Deng, MD, Xin Liu, MD, Min Xie, MD, Rui Zhao, MD, Liwei Ji, MD, Kuo Tang, Wei Yang, MD, Wei Ou, MD, Maodi Xie, Tao Li, MD, PhD

Diabetes db230264

https://doi.org/10.2337/db23-0264

Published: 25 August 2023

View article titled, Obesity enables NLRP3 activation and induces myocardial fibrosis via hyperacetylation of HADHa

Journal Articles

Keeping It in the Family: Consanguinity Reveals P4HTM as a Novel Syndromic Obesity Gene

Janine F. Felix, Struan F.A. Grant

Diabetes 2023;72(9):1184–1186

https://doi.org/10.2337/dbi23-0010

Published: 21 August 2023

View article titled, Keeping It in the Family: Consanguinity Reveals P4HTM as a Novel Syndromic Obesity Gene

Journal Articles

Abdominal Obesity Genetic Variants Predict Waist Circumference Regain After Weight Loss

Malene Revsbech Christiansen, Tuomas O. Kilpeläinen, Jeanne M. McCaffery

Diabetes 2023;72(10):1424–1432

https://doi.org/10.2337/db23-0131

Published: 26 July 2023

View article titled, Abdominal Obesity Genetic Variants Predict Waist Circumference Regain After Weight Loss

Journal Articles

In This Issue of Diabetes

Max Bingham, PhD

Diabetes 2023;72(8):1043–1044

https://doi.org/10.2337/db23-ti08

Published: 20 July 2023

View article titled, In This Issue of Diabetes

Meeting Abstracts

1793-PUB: Effects of Nonnutritive Sweeteners on Glycemic Indices in Healthy Persons, with Overweight or Obesity, or Diabetes—A Systematic Review and Meta-analysis of Randomized Controlled Trials

S. AMIRHOSSEIN GOLZAN, ALAN ESPINOSA, MOHAMMADMAHDI ABBASI, MINA MOVAHEDIAN, MOBINA FATHI, AZITA HEKMATDOOST

Diabetes 2023;72(Supplement_1):1793-PUB

https://doi.org/10.2337/db23-1793-PUB

Published: 23 June 2023

View article titled, 1793-PUB: Effects of Nonnutritive Sweeteners on Glycemic Indices in Healthy Persons, with Overweight or Obesity, or Diabetes—A Systematic Review and Meta-analysis of Randomized Controlled Trials

Meeting Abstracts

1832-PUB: SECRET—Screening and Educating Adolescents for Obesity

VIPUL CHAVDA, DHRUVI HASNANI, SHRIJI HASNANI, BHARAT SABOO, VINOD ABICHANDANI, ABHISHEK SHRIVASTAVA, SANTOSH JHA, BANSHI D. SABOO

Diabetes 2023;72(Supplement_1):1832-PUB

https://doi.org/10.2337/db23-1832-PUB

Published: 23 June 2023

View article titled, 1832-PUB: SECRET—Screening and Educating Adolescents for Obesity

Meeting Abstracts

1833-PUB: Effects of Lifestyle on Obesity and Hypertension in Adolescents—Data from Western India

DHRUVI HASNANI, SANTOSH JHA, BANSHI D. SABOO, SHRIJI HASNANI, SNEHAL JAMALPURE, VIPUL CHAVDA

Diabetes 2023;72(Supplement_1):1833-PUB

https://doi.org/10.2337/db23-1833-PUB

Published: 23 June 2023

View article titled, 1833-PUB: Effects of Lifestyle on Obesity and Hypertension in Adolescents—Data from Western India

Meeting Abstracts

51-OR: A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Dose-Finding Study of BI 456906 in People with Overweight/Obesity

CAREL LE ROUX, OREN STEEN, KATHRYN J. LUCAS, ELENA STARTSEVA, ANNA UNSELD, ANITA M. HENNIGE

Diabetes 2023;72(Supplement_1):51-OR

https://doi.org/10.2337/db23-51-OR

Published: 23 June 2023

View article titled, 51-OR: A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Dose-Finding Study of BI 456906 in People with Overweight/Obesity

Meeting Abstracts

52-OR: Effect of Oral Nonpeptide GLP-1 Receptor Agonist Orforglipron (LY3502970) in Participants with Obesity or Overweight—A Phase 2 Study

SEAN WHARTON, THOMAS BLEVINS, LISA B. CONNERY, JULIO ROSENSTOCK, SOHINI RAHA, KIEREN J. MATHER, AXEL HAUPT, DEBORAH A. ROBINS, EDWARD J. PRATT, CHRISTOF M. KAZDA, MANIGE KONIG

Diabetes 2023;72(Supplement_1):52-OR

https://doi.org/10.2337/db23-52-OR

Published: 23 June 2023

View article titled, 52-OR: Effect of Oral Nonpeptide GLP-1 Receptor Agonist Orforglipron (LY3502970) in Participants with Obesity or Overweight—A Phase 2 Study

Meeting Abstracts

131-OR: Glycemic Measures in Childhood as Predictors of Future Diabetes-Related Microvascular Complications

LAURA VAZQUEZ, ELSA VAZQUEZ ARREOLA, ROBERT L. HANSON, MADHUMITA SINHA

Diabetes 2023;72(Supplement_1):131-OR

https://doi.org/10.2337/db23-131-OR

Published: 23 June 2023

View article titled, 131-OR: Glycemic Measures in Childhood as Predictors of Future Diabetes-Related Microvascular Complications

Journal Articles

Reciprocal Regulation of Hepatic TGF-β1 and Foxo1 Controls Gluconeogenesis and Energy Expenditure

Quan Pan, Weiqi Ai, Yunmei Chen, Da Mi Kim, Zheng Shen, Wanbao Yang, Wen Jiang, Yuxiang Sun, Stephen Safe, Shaodong Guo

Diabetes 2023;72(9):1193–1206

https://doi.org/10.2337/db23-0180

Published: 21 June 2023

View article titled, Reciprocal Regulation of Hepatic TGF-β1 and Foxo1 Controls Gluconeogenesis and Energy Expenditure

Meeting Abstracts

1779-P: Lipotoxicity-Induced Beta-Cell Small Extracellular Vesicles Promote Beta-Cell Functional Failure through Activation of the TGFß/Smad3 Pathway

ABHISHEK ROY, ALEXANDRA HOFF, TRACY K. HER, KAMALNATH SANKARAN RAJAGOPALAN, DANIELA D. MALTAIS, ALEKSEY MATVEYENKO, NAUREEN JAVEED

Diabetes 2023;72(Supplement_1):1779-P

https://doi.org/10.2337/db23-1779-P

Published: 20 June 2023

View article titled, 1779-P: Lipotoxicity-Induced Beta-Cell Small Extracellular Vesicles Promote Beta-Cell Functional Failure through Activation of the TGFß/Smad3 Pathway

Meeting Abstracts

1284-P: Prediabetes with Obesity Is a Major Risk Factor for NAFLD and Liver Fibrosis

EDDISON GODINEZ LEIVA, ROMINA LOMONACO, SULAV SHRESTHA, STEPHEN A. MARANGI, XIAOFEI CHI, SRILAXMI KALAVALAPALLI, SHWETHA S. SHETTY, ANDREA ORTIZ ROCHA, ENRIQUE VALDEZ SAENZ, MARIA A. GONZALEZ, LYDIA MANSOUR, MARIANNA M. CALVET, DIANA BARB, APRIL MATHEWS, ANU SHARMA, KENNETH CUSI

Diabetes 2023;72(Supplement_1):1284-P

https://doi.org/10.2337/db23-1284-P

Published: 20 June 2023

View article titled, 1284-P: Prediabetes with Obesity Is a Major Risk Factor for NAFLD and Liver Fibrosis

Meeting Abstracts

321-OR: Differential Associations of Obesity and Metabolic Syndrome with Polyneuropathy in Early Type 2 Diabetes and Normal Glucose Tolerance

GUNDEGA SIPOLA, ALEXANDER STROM, MARIA BOMBRICH, ROBERT WAGNER, DAN ZIEGLER, MICHAEL RODEN, GIDON J. BÖNHOF, GDS GROUP

Diabetes 2023;72(Supplement_1):321-OR

https://doi.org/10.2337/db23-321-OR

Published: 20 June 2023

View article titled, 321-OR: Differential Associations of Obesity and Metabolic Syndrome with Polyneuropathy in Early Type 2 Diabetes and Normal Glucose Tolerance

Meeting Abstracts

265-LB: Human Skeletal Muscle Mitochondrial Dynamics across the Insulin-Sensitivity Spectrum

CHRISTOPHER L. AXELROD, WAGNER S. DANTAS, ELIZABETH R.M. ZUNICA, KATHRYN BELMONT, ELIZABETH C. HEINTZ, GANGARAO DAVULURI, JACOB T. MEY, MELISSA ERICKSON, HISASHI FUJIOKA, CIARAN FEALY, CHARLES L. HOPPEL, JOHN P. KIRWAN

Diabetes 2023;72(Supplement_1):265-LB

https://doi.org/10.2337/db23-265-LB

Published: 20 June 2023

View article titled, 265-LB: Human Skeletal Muscle Mitochondrial Dynamics across the Insulin-Sensitivity Spectrum

Meeting Abstracts

273-LB: The Effect of Bispecific GLP-1R/GLP-2R Agonist Compared with Dual GLP-1R/GLP-2R Agonist and Dual GLP-1R/GIPR Agonist in Diet-Induced Obesity Mouse Model

TIMOTHY OH, SANG-IN YANG, JAEIL ROH, JEE YOON SUNG

Diabetes 2023;72(Supplement_1):273-LB

https://doi.org/10.2337/db23-273-LB

Published: 20 June 2023

View article titled, 273-LB: The Effect of Bispecific GLP-1R/GLP-2R Agonist Compared with Dual GLP-1R/GLP-2R Agonist and Dual GLP-1R/GIPR Agonist in Diet-Induced Obesity Mouse Model

Meeting Abstracts

272-LB: Obesity-Induced Mitochondrial Fragmentation in White Adipocytes Is Controlled by the Small GTPase RalA

WENMIN XIA, PREETHI VEERAGANDHAM, YU CAO, YAYUN XU, TORREY E. RHYNE, YING JONES, RUTH T. YU, MIKAEL RYDÉN, MARTIN WABITSCH, ALAN SALTIEL

Diabetes 2023;72(Supplement_1):272-LB

https://doi.org/10.2337/db23-272-LB

Published: 20 June 2023

View article titled, 272-LB: Obesity-Induced Mitochondrial Fragmentation in White Adipocytes Is Controlled by the Small GTPase RalA

NARROW

In This Issue of Diabetes

Decoding the Mechanisms Behind Early Weaning–Driven Obesity and the Leucine “Solution”

Treg-specific CD226 Deletion Reduces Diabetes Incidence in NOD Mice by Improving Regulatory T Cell Stability

Obesity enables NLRP3 activation and induces myocardial fibrosis via hyperacetylation of HADHa

Keeping It in the Family: Consanguinity Reveals P4HTM as a Novel Syndromic Obesity Gene

Abdominal Obesity Genetic Variants Predict Waist Circumference Regain After Weight Loss

In This Issue of Diabetes

1793-PUB: Effects of Nonnutritive Sweeteners on Glycemic Indices in Healthy Persons, with Overweight or Obesity, or Diabetes—A Systematic Review and Meta-analysis of Randomized Controlled Trials

1832-PUB: SECRET—Screening and Educating Adolescents for Obesity

1833-PUB: Effects of Lifestyle on Obesity and Hypertension in Adolescents—Data from Western India

51-OR: A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Dose-Finding Study of BI 456906 in People with Overweight/Obesity

52-OR: Effect of Oral Nonpeptide GLP-1 Receptor Agonist Orforglipron (LY3502970) in Participants with Obesity or Overweight—A Phase 2 Study

131-OR: Glycemic Measures in Childhood as Predictors of Future Diabetes-Related Microvascular Complications

Reciprocal Regulation of Hepatic TGF-β1 and Foxo1 Controls Gluconeogenesis and Energy Expenditure

1779-P: Lipotoxicity-Induced Beta-Cell Small Extracellular Vesicles Promote Beta-Cell Functional Failure through Activation of the TGFß/Smad3 Pathway

1284-P: Prediabetes with Obesity Is a Major Risk Factor for NAFLD and Liver Fibrosis

321-OR: Differential Associations of Obesity and Metabolic Syndrome with Polyneuropathy in Early Type 2 Diabetes and Normal Glucose Tolerance

265-LB: Human Skeletal Muscle Mitochondrial Dynamics across the Insulin-Sensitivity Spectrum

273-LB: The Effect of Bispecific GLP-1R/GLP-2R Agonist Compared with Dual GLP-1R/GLP-2R Agonist and Dual GLP-1R/GIPR Agonist in Diet-Induced Obesity Mouse Model

272-LB: Obesity-Induced Mitochondrial Fragmentation in White Adipocytes Is Controlled by the Small GTPase RalA

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