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Journal Articles

Treg-specific CD226 Deletion Reduces Diabetes Incidence in NOD Mice by Improving Regulatory T Cell Stability

Puchong Thirawatananond, Matthew E. Brown, Lindsey K. Sachs, Juan M. Arnoletti, Wen-I Yeh, Amanda L. Posgai, Melanie R. Shapiro, Yi-Guang Chen, Todd M. Brusko

Diabetes db230307

https://doi.org/10.2337/db23-0307

Published: 25 August 2023

View article titled, Treg-specific CD226 Deletion Reduces Diabetes Incidence in NOD Mice by Improving Regulatory T Cell Stability

Journal Articles

A Plasma miR-193b-365 Signature Combined With Age and Glycemic Status Predicts Response to Lactococcus lactis–Based Antigen-Specific Immunotherapy in New-Onset Type 1 Diabetes

Gabriele Sassi, Giada Licata, Giuliana Ventriglia, Amber Wouters, Pierre Lemaitre, Ruth Seurinck, Alessia Mori, Giuseppina Emanuela Grieco, Samal Bissenova, Darcy Ellis, Silvia Caluwaerts, Pieter Rottiers, Niels Vandamme, Chantal Mathieu, Francesco Dotta, Conny Gysemans, Guido Sebastiani

Diabetes 2023;72(10):1470–1482

https://doi.org/10.2337/db22-0852

Published: 26 July 2023

View article titled, A Plasma miR-193b-365 Signature Combined With Age and Glycemic Status Predicts Response to Lactococcus lactis–Based Antigen-Specific Immunotherapy in New-Onset Type 1 Diabetes

Meeting Abstracts

743-P: Delayed Diabetes with Proinsulin mRNA Vaccines in NOD Mice

TIMOTHY P. FOSTER, MICHAEL J. HALLER, DESMOND SCHATZ, CLIVE WASSERFALL, ELIAS SAYOUR

Diabetes 2023;72(Supplement_1):743-P

https://doi.org/10.2337/db23-743-P

Published: 20 June 2023

View article titled, 743-P: Delayed Diabetes with Proinsulin mRNA Vaccines in NOD Mice

Meeting Abstracts

1488-P: Reduced iPLA2b Expression in T-Lymphocytes Decreases Proinflammatory Eicosanoid Production and Cytokine Secretion Delaying Type 1 Diabetes Development in NOD Mice

TAYLEUR WHITE, SASANKA RAMANADHAM, TERESA P. DILORENZO, CHARLES E. CHALFANT

Diabetes 2023;72(Supplement_1):1488-P

https://doi.org/10.2337/db23-1488-P

Published: 20 June 2023

View article titled, 1488-P: Reduced iPLA2b Expression in T-Lymphocytes Decreases Proinflammatory Eicosanoid Production and Cytokine Secretion Delaying Type 1 Diabetes Development in NOD Mice

Journal Articles

Tracking Ca²⁺ Dynamics in NOD Mouse Islets During Spontaneous Diabetes Development

Sandra Postić, Johannes Pfabe, Srdjan Sarikas, Barbara Ehall, Thomas Pieber, Dean Korošak, Marjan Slak Rupnik, Ya-Chi Huang

Diabetes 2023;72(9):1251–1261

https://doi.org/10.2337/db22-0952

Published: 31 May 2023

View article titled, Tracking Ca2+ Dynamics in NOD Mouse Islets During Spontaneous Diabetes Development

Journal Articles

Immunotherapy With Low-Dose IL-2/CD25 Prevents β-Cell Dysfunction and Dysglycemia in Prediabetic NOD Mice

Farhan M. Qureshi, Julia K. Panzer, Janika Põder, Thomas R. Malek, Alejandro Caicedo

Diabetes 2023;72(6):769–780

https://doi.org/10.2337/db22-0482

Published: 20 March 2023

View article titled, Immunotherapy With Low-Dose IL-2/CD25 Prevents β-Cell Dysfunction and Dysglycemia in Prediabetic NOD Mice

Journal Articles

Carbonyl Posttranslational Modification Associated With Early-Onset Type 1 Diabetes Autoimmunity

Mei-Ling Yang, Sean E. Connolly, Renelle J. Gee, TuKiet T. Lam, Jean Kanyo, Jian Peng, Perrin Guyer, Farooq Syed, Hubert M. Tse, Steven G. Clarke, Catherine F. Clarke, Eddie A. James, Cate Speake, Carmella Evans-Molina, Peter Arvan, Kevan C. Herold, Li Wen, Mark J. Mamula

Diabetes 2022;71(9):1979–1993

https://doi.org/10.2337/db21-0989

Published: 22 June 2022

View article titled, Carbonyl Posttranslational Modification Associated With Early-Onset Type 1 Diabetes Autoimmunity

Meeting Abstracts

79-OR: Conventionalization from Cecal Transplant Recipients Protects Against Type 1 Diabetes Development in Germ-Free NOD Mice

SAMUEL PAN, XUE-SONG ZHANG, MARTIN J. BLASER

Diabetes 2022;71(Supplement_1):79-OR

https://doi.org/10.2337/db22-79-OR

Published: 01 June 2022

View article titled, 79-OR: Conventionalization from Cecal Transplant Recipients Protects Against Type 1 Diabetes Development in Germ-Free NOD Mice

Meeting Abstracts

258-LB: ICAM-1 Abundance Is Increased in Pancreatic Islets of Hyperglycemic NOD Mice and Is Rapidly Upregulated by NF-kB in Pancreatic Beta Cells

THOMAS MARTIN, SUSAN BURKE, SUJOY GHOSH, MICHAEL D. KARLSTAD, JASON COLLIER

Diabetes 2022;71(Supplement_1):258-LB

https://doi.org/10.2337/db22-258-LB

Published: 01 June 2022

View article titled, 258-LB: ICAM-1 Abundance Is Increased in Pancreatic Islets of Hyperglycemic NOD Mice and Is Rapidly Upregulated by NF-kB in Pancreatic Beta Cells

Meeting Abstracts

74-OR: Adoptively Transferred T Lymphocytes with Reduced iPLA2b Expression Delays Type 1 Diabetes Development in NOD Mice

TAYLEUR WHITE, CHARLES CHALFANT, TERESA P. DILORENZO, SASANKA RAMANADHAM, DANIEL STEPHENSON

Diabetes 2022;71(Supplement_1):74-OR

https://doi.org/10.2337/db22-74-OR

Published: 01 June 2022

View article titled, 74-OR: Adoptively Transferred T Lymphocytes with Reduced iPLA2b Expression Delays Type 1 Diabetes Development in NOD Mice

Journal Articles

Identification of Novel Disease-Relevant Genes and Pathways in the Pathogenesis of Type 1 Diabetes: A Potential Defect in Pancreatic Iron Homeostasis

Linda Yip, Reem Alkhataybeh, Cariel Taylor, Rebecca Fuhlbrigge, C. Garrison Fathman

Diabetes 2022;71(7):1490–1507

https://doi.org/10.2337/db21-0948

Published: 02 May 2022

View article titled, Identification of Novel Disease-Relevant Genes and Pathways in the Pathogenesis of Type 1 Diabetes: A Potential Defect in Pancreatic Iron Homeostasis

Journal Articles

PTPN2 Regulates the Interferon Signaling and Endoplasmic Reticulum Stress Response in Pancreatic β-Cells in Autoimmune Diabetes

Bernat Elvira, Valerie Vandenbempt, Julia Bauzá-Martinez, Raphaël Crutzen, Javier Negueruela, Hazem Ibrahim, Matthew L. Winder, Manoja K. Brahma, Beata Vekeriotaite, Pieter-Jan Martens, Sumeet Pal Singh, Fernando Rossello, Pascale Lybaert, Timo Otonkoski, Conny Gysemans, Wei Wu, Esteban N. Gurzov

Diabetes 2022;71(4):653–668

https://doi.org/10.2337/db21-0443

Published: 19 January 2022

View article titled, PTPN2 Regulates the Interferon Signaling and Endoplasmic Reticulum Stress Response in Pancreatic β-Cells in Autoimmune Diabetes

Journal Articles

Tolerogenic Delivery of a Hybrid Insulin Peptide Markedly Prolongs Islet Graft Survival in the NOD Mouse

Braxton L. Jamison, James E. DiLisio, K. Scott Beard, Tobias Neef, Brenda Bradley, Jessica Goodman, Ronald G. Gill, Stephen D. Miller, Rocky L. Baker, Kathryn Haskins

Diabetes 2022;71(3):483–496

https://doi.org/10.2337/db20-1170

Published: 18 January 2022

View article titled, Tolerogenic Delivery of a Hybrid Insulin Peptide Markedly Prolongs Islet Graft Survival in the NOD Mouse

Journal Articles

CD8⁺ T Cells Variably Recognize Native Versus Citrullinated GRP78 Epitopes in Type 1 Diabetes

Diabetes 2021;70(12):2879–2891

https://doi.org/10.2337/db21-0259

Published: 24 September 2021

View article titled, CD8+ T Cells Variably Recognize Native Versus Citrullinated GRP78 Epitopes in Type 1 Diabetes

Journal Articles

Coxsackievirus B Vaccines Prevent Infection-Accelerated Diabetes in NOD Mice and Have No Disease-Inducing Effect

Virginia M. Stone, Marta Butrym, Minna M. Hankaniemi, Amir-Babak Sioofy-Khojine, Vesa P. Hytönen, Heikki Hyöty, Malin Flodström-Tullberg

Diabetes 2021;70(12):2871–2878

https://doi.org/10.2337/db21-0193

Published: 08 September 2021

View article titled, Coxsackievirus B Vaccines Prevent Infection-Accelerated Diabetes in NOD Mice and Have No Disease-Inducing Effect

Journal Articles

Multicomponent Plasmid Protects Mice From Spontaneous Autoimmune Diabetes

Philippe P. Pagni, Jay Chaplin, Michael Wijaranakula, Johnna D. Wesley, Jaimie Granger, Justen Cracraft, Conor O’Brien, Nikole Perdue, Vijetha Kumar, Shangjin Li, Sowbarnika Sachithanantham Ratliff, Allie Roach, Ayesha Misquith, Chung-leung Chan, Ken Coppieters, Matthias von Herrath

Diabetes 2022;71(1):157–169

https://doi.org/10.2337/db21-0327

Published: 13 August 2021

View article titled, Multicomponent Plasmid Protects Mice From Spontaneous Autoimmune Diabetes

Journal Articles

Erratum. Microencapsulated G3C Hybridoma Cell Graft Delays the Onset of Spontaneous Diabetes in NOD Mice by an Expansion of Gitr⁺ Treg Cells. Diabetes 2020;69: 965–980

Luigi Cari, Pia Montanucci, Giuseppe Basta, Maria G. Petrillo, Erika Ricci, Teresa Pescara, Alessia Greco, Sabrina Cipriani, Jun Shimizu, Graziella Migliorati, Giuseppe Nocentini, Riccardo Calafiore, Carlo Riccardi

Diabetes 2021;70(6):1414

https://doi.org/10.2337/db21-er06a

Published: 02 July 2021

View article titled, Erratum. Microencapsulated G3C Hybridoma Cell Graft Delays the Onset of Spontaneous Diabetes in NOD Mice by an Expansion of Gitr+ Treg Cells. Diabetes 2020;69: 965–980

Meeting Abstracts

754-P: SerpinB1 Delays T1D Progression and Improves Glucose Homeostasis in NOD Mice

GIORGIO BASILE, HYUNKI KIM, LING XIAO, JIANG HU, HUAFANG WANG, PHILIP PEMBERTON, ROHIT KULKARNI

Diabetes 2021;70(Supplement_1):754-P

https://doi.org/10.2337/db21-754-P

Published: 01 June 2021

View article titled, 754-P: SerpinB1 Delays T1D Progression and Improves Glucose Homeostasis in NOD Mice

Meeting Abstracts

114-OR: Overexpression of Alpha-1 Antitrypsin in MSCs Delays Onset of Type 1 Diabetes in the NOD Mice by Increasing Their Antiinflammatory and Protection Functions

HUA WEI, WENYU GOU, CHARLIE STRANGE, HONGJUN WANG

Diabetes 2021;70(Supplement_1):114-OR

https://doi.org/10.2337/db21-114-OR

Published: 01 June 2021

View article titled, 114-OR: Overexpression of Alpha-1 Antitrypsin in MSCs Delays Onset of Type 1 Diabetes in the NOD Mice by Increasing Their Antiinflammatory and Protection Functions

Meeting Abstracts

110-OR: MDA5-Dependent Responses Can Influence Spontaneous and Virus-Accelerated T1D Onset

SAMUEL I. BLUM, YI-GUANG CHEN, HUBERT M. TSE

Diabetes 2021;70(Supplement_1):110-OR

https://doi.org/10.2337/db21-110-OR

Published: 01 June 2021

View article titled, 110-OR: MDA5-Dependent Responses Can Influence Spontaneous and Virus-Accelerated T1D Onset

NARROW

Treg-specific CD226 Deletion Reduces Diabetes Incidence in NOD Mice by Improving Regulatory T Cell Stability

A Plasma miR-193b-365 Signature Combined With Age and Glycemic Status Predicts Response to Lactococcus lactis–Based Antigen-Specific Immunotherapy in New-Onset Type 1 Diabetes

743-P: Delayed Diabetes with Proinsulin mRNA Vaccines in NOD Mice

1488-P: Reduced iPLA2b Expression in T-Lymphocytes Decreases Proinflammatory Eicosanoid Production and Cytokine Secretion Delaying Type 1 Diabetes Development in NOD Mice

Tracking Ca²⁺ Dynamics in NOD Mouse Islets During Spontaneous Diabetes Development

Immunotherapy With Low-Dose IL-2/CD25 Prevents β-Cell Dysfunction and Dysglycemia in Prediabetic NOD Mice

Carbonyl Posttranslational Modification Associated With Early-Onset Type 1 Diabetes Autoimmunity

79-OR: Conventionalization from Cecal Transplant Recipients Protects Against Type 1 Diabetes Development in Germ-Free NOD Mice

258-LB: ICAM-1 Abundance Is Increased in Pancreatic Islets of Hyperglycemic NOD Mice and Is Rapidly Upregulated by NF-kB in Pancreatic Beta Cells

74-OR: Adoptively Transferred T Lymphocytes with Reduced iPLA2b Expression Delays Type 1 Diabetes Development in NOD Mice

Identification of Novel Disease-Relevant Genes and Pathways in the Pathogenesis of Type 1 Diabetes: A Potential Defect in Pancreatic Iron Homeostasis

PTPN2 Regulates the Interferon Signaling and Endoplasmic Reticulum Stress Response in Pancreatic β-Cells in Autoimmune Diabetes

Tolerogenic Delivery of a Hybrid Insulin Peptide Markedly Prolongs Islet Graft Survival in the NOD Mouse

CD8⁺ T Cells Variably Recognize Native Versus Citrullinated GRP78 Epitopes in Type 1 Diabetes

Coxsackievirus B Vaccines Prevent Infection-Accelerated Diabetes in NOD Mice and Have No Disease-Inducing Effect

Multicomponent Plasmid Protects Mice From Spontaneous Autoimmune Diabetes

Erratum. Microencapsulated G3C Hybridoma Cell Graft Delays the Onset of Spontaneous Diabetes in NOD Mice by an Expansion of Gitr⁺ Treg Cells. Diabetes 2020;69: 965–980

754-P: SerpinB1 Delays T1D Progression and Improves Glucose Homeostasis in NOD Mice

114-OR: Overexpression of Alpha-1 Antitrypsin in MSCs Delays Onset of Type 1 Diabetes in the NOD Mice by Increasing Their Antiinflammatory and Protection Functions

110-OR: MDA5-Dependent Responses Can Influence Spontaneous and Virus-Accelerated T1D Onset

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