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Journal Articles

Lysine 117 Residue Is Essential for the Function of the Hepatocyte Nuclear Factor 1α

Yuan Chu, Long Zhao, Xian Liu, Hui Chen, Chen Zhao, Sicong Chen, Shensi Xiang, Jun Lu, Xiaofang Wang, Yue Wan, Diandian Dong, Songhui Yao, Changyan Li, Ronghua Yin, Guangming Ren, Xiaoming Yang, Miao Yu

Diabetes 2023;72(10):1502–1516

https://doi.org/10.2337/db22-0672

Published: 13 July 2023

View article titled, Lysine 117 Residue Is Essential for the Function of the Hepatocyte Nuclear Factor 1α

Journal Articles

Reciprocal Regulation of Hepatic TGF-β1 and Foxo1 Controls Gluconeogenesis and Energy Expenditure

Quan Pan, Weiqi Ai, Yunmei Chen, Da Mi Kim, Zheng Shen, Wanbao Yang, Wen Jiang, Yuxiang Sun, Stephen Safe, Shaodong Guo

Diabetes 2023;72(9):1193–1206

https://doi.org/10.2337/db23-0180

Published: 21 June 2023

View article titled, Reciprocal Regulation of Hepatic TGF-β1 and Foxo1 Controls Gluconeogenesis and Energy Expenditure

Journal Articles

Trajectories of Liver Fibrosis and Gene Expression Profiles in Nonalcoholic Fatty Liver Disease Associated With Diabetes

Saori Sako, Yumie Takeshita, Hiroaki Takayama, Hisanori Goto, Yujiro Nakano, Hitoshi Ando, Hiromasa Tsujiguchi, Tatsuya Yamashita, Kuniaki Arai, Shuichi Kaneko, Hiroyuki Nakamura, Kenichi Harada, Masao Honda, Toshinari Takamura

Diabetes 2023;72(9):1297–1306

https://doi.org/10.2337/db22-0933

Published: 21 June 2023

View article titled, Trajectories of Liver Fibrosis and Gene Expression Profiles in Nonalcoholic Fatty Liver Disease Associated With Diabetes

Meeting Abstracts

1557-P: Ctcfl Is a Fasting-Induced Epigenetic Regulator of Lipid Metabolism and Ketogenesis in the Liver

VISSARION EFTHYMIOU, LINDSAY POULOS, LEON STRAUB, VALERIE NAVARRETE, BERKCAN OZTURK, SORAVIS OSATAPHAN, JEREMY I. CHIMENE-WEISS, MARY-ELIZABETH PATTI

Diabetes 2023;72(Supplement_1):1557-P

https://doi.org/10.2337/db23-1557-P

Published: 20 June 2023

View article titled, 1557-P: Ctcfl Is a Fasting-Induced Epigenetic Regulator of Lipid Metabolism and Ketogenesis in the Liver

Meeting Abstracts

1556-P: Hepatic AMP-Activated Protein Kinase Governs Adaptations in Liver Glucose Fluxes and Lipid Homeostasis in Response to Exercise Training in Mice

CURTIS C. HUGHEY, DEANNA BRACY, LOUISE LANTIER, MARC FORETZ, BENOIT VIOLLET, DAVID WASSERMAN

Diabetes 2023;72(Supplement_1):1556-P

https://doi.org/10.2337/db23-1556-P

Published: 20 June 2023

View article titled, 1556-P: Hepatic AMP-Activated Protein Kinase Governs Adaptations in Liver Glucose Fluxes and Lipid Homeostasis in Response to Exercise Training in Mice

Meeting Abstracts

294-OR: Hepatic Integrin ß1 Subunit Is Required for Liver Insulin Resistance but Not Fatty Liver in Diet-Induced Obese Mice

ELIJAH TREFTS, KAKALI GHOSHAL, ALLISON V. DO, AMANDA GUERIN, CHRISTOPHER GUAN, DEANNA BRACY, LOUISE LANTIER, ROY ZENT, AMBRA POZZI, DAVID H. WASSERMAN

Diabetes 2023;72(Supplement_1):294-OR

https://doi.org/10.2337/db23-294-OR

Published: 20 June 2023

View article titled, 294-OR: Hepatic Integrin ß1 Subunit Is Required for Liver Insulin Resistance but Not Fatty Liver in Diet-Induced Obese Mice

Meeting Abstracts

293-OR: Macrophage-Derived Interleukin-12 Regulates Obesity-Mediated Insulin Resistance in the Liver

RANDALL H. FRIEDLINE, MAHAA ALBUSHARIF, ALLISON M. KIM, LAUREN H. KIM, NATALIE M. BAEZ TORRES, LAUREN A. TAUER, XIAODI HU, JASON K. KIM

Diabetes 2023;72(Supplement_1):293-OR

https://doi.org/10.2337/db23-293-OR

Published: 20 June 2023

View article titled, 293-OR: Macrophage-Derived Interleukin-12 Regulates Obesity-Mediated Insulin Resistance in the Liver

Meeting Abstracts

1598-P: MIF-upregulated CD74 in Liver Contributes to the Development of NAFLD

LIUJUN CHEN, LISHA LI, YIHENG HUANG, XI CHEN, YADAN QI, HAIBIN TONG, HONG WU, DAKE QI

Diabetes 2023;72(Supplement_1):1598-P

https://doi.org/10.2337/db23-1598-P

Published: 20 June 2023

View article titled, 1598-P: MIF-upregulated CD74 in Liver Contributes to the Development of NAFLD

Meeting Abstracts

257-LB: Defining the Stage-Dependent Transcriptome and Methylome in the Mouse Liver during Perinatal Metabolic Maturation

SEIICHI YANO, NAOICHI SATO, HIROMITSU ARAKI, FUMIHITO MIURA, TAKASHI ITO, YOSHIHIRO OGAWA

Diabetes 2023;72(Supplement_1):257-LB

https://doi.org/10.2337/db23-257-LB

Published: 20 June 2023

View article titled, 257-LB: Defining the Stage-Dependent Transcriptome and Methylome in the Mouse Liver during Perinatal Metabolic Maturation

Meeting Abstracts

1577-P: Hepatic Steatosis and Glucose Intolerance in Liver-Specific Estrogen Receptor Alpha Knockout Mice

FELIPE SUCUPIRA, LAYANNE ARAUJO, JOAO PAULO CAMPOREZ

Diabetes 2023;72(Supplement_1):1577-P

https://doi.org/10.2337/db23-1577-P

Published: 20 June 2023

View article titled, 1577-P: Hepatic Steatosis and Glucose Intolerance in Liver-Specific Estrogen Receptor Alpha Knockout Mice

Meeting Abstracts

303-OR: Maternal High-Fat Diet Alters the Gut Microbiota–Liver Circadian Rhythms and Results In Metabolic Dysfunction in Offspring

LU DING, JIEYING LIU, QIAN ZHANG, XINHUA XIAO

Diabetes 2023;72(Supplement_1):303-OR

https://doi.org/10.2337/db23-303-OR

Published: 20 June 2023

View article titled, 303-OR: Maternal High-Fat Diet Alters the Gut Microbiota–Liver Circadian Rhythms and Results In Metabolic Dysfunction in Offspring

Meeting Abstracts

1683-P: High-Fat Diet Downregulates CREG1 in the Liver via DNA Methylation

YANMEI QI, JIE LIU, JOSHUA C. CHAO, SAUM A. RAHIMI, LEONARD Y. LEE, SHAOHUA LI

Diabetes 2023;72(Supplement_1):1683-P

https://doi.org/10.2337/db23-1683-P

Published: 20 June 2023

View article titled, 1683-P: High-Fat Diet Downregulates CREG1 in the Liver via DNA Methylation

Meeting Abstracts

1237-P: Proteomic Indicators of Metabolic Health in Diabetes and Social Vulnerability

MISSY SIMPSON, RACHEL OSTROFF, STEPHEN A. WILLIAMS, NAVEED SATTAR

Diabetes 2023;72(Supplement_1):1237-P

https://doi.org/10.2337/db23-1237-P

Published: 20 June 2023

View article titled, 1237-P: Proteomic Indicators of Metabolic Health in Diabetes and Social Vulnerability

Meeting Abstracts

1569-P: Lysophosphatidic Acid Mediates Inflammation in Liver and White Adipose Tissue in a Rat Model of 1-acyl-sn-glycerol-3-phosphate Acyltransferase 2 Deficiency

IKKI SAKUMA, RAFAEL C. GASPAR, PANU LUUKKONEN, MARIO KAHN, SUE MURRAY, VARMAN SAMUEL, KITT PETERSEN, GERALD I. SHULMAN

Diabetes 2023;72(Supplement_1):1569-P

https://doi.org/10.2337/db23-1569-P

Published: 20 June 2023

View article titled, 1569-P: Lysophosphatidic Acid Mediates Inflammation in Liver and White Adipose Tissue in a Rat Model of 1-acyl-sn-glycerol-3-phosphate Acyltransferase 2 Deficiency

Meeting Abstracts

759-P: Changes in Liver Fat in Patients with Type 2 Diabetes by Presence of Genetic Hepatic Steatosis in the SURPASS-3 MRI Substudy

KENNETH CUSI, AMALIA GASTALDELLI, LAURA FERNANDEZ LANDO, MINZHI LIU, AMELIA TORCELLO-GOMEZ, ÁNGEL RODRÍGUEZ

Diabetes 2023;72(Supplement_1):759-P

https://doi.org/10.2337/db23-759-P

Published: 20 June 2023

View article titled, 759-P: Changes in Liver Fat in Patients with Type 2 Diabetes by Presence of Genetic Hepatic Steatosis in the SURPASS-3 MRI Substudy

Meeting Abstracts

758-P: Changes in Liver and Abdominal Fat in Tirzepatide-Treated Patients Achieving Normoglycemia in the SURPASS-3 MRI Substudy

ÁNGEL RODRÍGUEZ, KENNETH CUSI, AMALIA GASTALDELLI, CLAUDIA NICOLAY, AMELIA TORCELLO-GOMEZ, LAURA FERNANDEZ LANDO

Diabetes 2023;72(Supplement_1):758-P

https://doi.org/10.2337/db23-758-P

Published: 20 June 2023

View article titled, 758-P: Changes in Liver and Abdominal Fat in Tirzepatide-Treated Patients Achieving Normoglycemia in the SURPASS-3 MRI Substudy

Meeting Abstracts

1594-P: Interorgan Insulin-Leptin Signal Cross Talk Originating in the Liver Enhances Survival under Food-Shortage Conditions

KEI TAKAHASHI, TETSUYA YAMADA, HIDEKI KATAGIRI

Diabetes 2023;72(Supplement_1):1594-P

https://doi.org/10.2337/db23-1594-P

Published: 20 June 2023

View article titled, 1594-P: Interorgan Insulin-Leptin Signal Cross Talk Originating in the Liver Enhances Survival under Food-Shortage Conditions

Meeting Abstracts

1587-P: The NADPH Oxidase 4 Regulates Anti-inflammatory Signals to Modulate Lipid Depot Distribution between Adipose Tissue and Liver

ILDIKO SZANTO

Diabetes 2023;72(Supplement_1):1587-P

https://doi.org/10.2337/db23-1587-P

Published: 20 June 2023

View article titled, 1587-P: The NADPH Oxidase 4 Regulates Anti-inflammatory Signals to Modulate Lipid Depot Distribution between Adipose Tissue and Liver

Meeting Abstracts

1583-P: Dynamic Tracking and Identification of Liver-Specific Secretory Proteins in the Circulation of Live Mice

KWANG-EUN KIM, JAE MYOUNG SUH

Diabetes 2023;72(Supplement_1):1583-P

https://doi.org/10.2337/db23-1583-P

Published: 20 June 2023

View article titled, 1583-P: Dynamic Tracking and Identification of Liver-Specific Secretory Proteins in the Circulation of Live Mice

Meeting Abstracts

617-P: Time in Range following Mealtime Protein Supplementation Is Predicted by Liver Health and ß-Cell Function in Adults with Type 2 Diabetes

KIERAN SMITH, GUY TAYLOR, MARK WALKER, KELLY A. BOWDEN DAVIES, EMMA J. STEVENSON, DANIEL J. WEST

Diabetes 2023;72(Supplement_1):617-P

https://doi.org/10.2337/db23-617-P

Published: 20 June 2023

View article titled, 617-P: Time in Range following Mealtime Protein Supplementation Is Predicted by Liver Health and ß-Cell Function in Adults with Type 2 Diabetes

NARROW

Lysine 117 Residue Is Essential for the Function of the Hepatocyte Nuclear Factor 1α

Reciprocal Regulation of Hepatic TGF-β1 and Foxo1 Controls Gluconeogenesis and Energy Expenditure

Trajectories of Liver Fibrosis and Gene Expression Profiles in Nonalcoholic Fatty Liver Disease Associated With Diabetes

1557-P: Ctcfl Is a Fasting-Induced Epigenetic Regulator of Lipid Metabolism and Ketogenesis in the Liver

1556-P: Hepatic AMP-Activated Protein Kinase Governs Adaptations in Liver Glucose Fluxes and Lipid Homeostasis in Response to Exercise Training in Mice

294-OR: Hepatic Integrin ß1 Subunit Is Required for Liver Insulin Resistance but Not Fatty Liver in Diet-Induced Obese Mice

293-OR: Macrophage-Derived Interleukin-12 Regulates Obesity-Mediated Insulin Resistance in the Liver

1598-P: MIF-upregulated CD74 in Liver Contributes to the Development of NAFLD

257-LB: Defining the Stage-Dependent Transcriptome and Methylome in the Mouse Liver during Perinatal Metabolic Maturation

1577-P: Hepatic Steatosis and Glucose Intolerance in Liver-Specific Estrogen Receptor Alpha Knockout Mice

303-OR: Maternal High-Fat Diet Alters the Gut Microbiota–Liver Circadian Rhythms and Results In Metabolic Dysfunction in Offspring

1683-P: High-Fat Diet Downregulates CREG1 in the Liver via DNA Methylation

1237-P: Proteomic Indicators of Metabolic Health in Diabetes and Social Vulnerability

1569-P: Lysophosphatidic Acid Mediates Inflammation in Liver and White Adipose Tissue in a Rat Model of 1-acyl-sn-glycerol-3-phosphate Acyltransferase 2 Deficiency

759-P: Changes in Liver Fat in Patients with Type 2 Diabetes by Presence of Genetic Hepatic Steatosis in the SURPASS-3 MRI Substudy

758-P: Changes in Liver and Abdominal Fat in Tirzepatide-Treated Patients Achieving Normoglycemia in the SURPASS-3 MRI Substudy

1594-P: Interorgan Insulin-Leptin Signal Cross Talk Originating in the Liver Enhances Survival under Food-Shortage Conditions

1587-P: The NADPH Oxidase 4 Regulates Anti-inflammatory Signals to Modulate Lipid Depot Distribution between Adipose Tissue and Liver

1583-P: Dynamic Tracking and Identification of Liver-Specific Secretory Proteins in the Circulation of Live Mice

617-P: Time in Range following Mealtime Protein Supplementation Is Predicted by Liver Health and ß-Cell Function in Adults with Type 2 Diabetes

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