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Meeting Abstracts

512-P: Single-Cell RNA-Sequencing Identifies Novel Molecular Targets of Endothelial MicroRNA-200b in the Diabetic Ischemic Wound

KANHAIYA SINGH, MANISHEKHAR KUMAR, SUJIT K. MOHANTY, SAVITA KHANNA, SASHWATI ROY, CHANDAN K. SEN

Diabetes 2023;72(Supplement_1):512-P

https://doi.org/10.2337/db23-512-P

Published: 20 June 2023

View article titled, 512-P: Single-Cell RNA-Sequencing Identifies Novel Molecular Targets of Endothelial MicroRNA-200b in the Diabetic Ischemic Wound

Meeting Abstracts

511-P: Is It Reasonable to Treat Infected Diabetic Foot Ulcers by Autologous Cell Therapy in Patients with Severe Ischemia?

MICHAL DUBSKY, JITKA HUSÁKOVÁ, VLADIMIRA FEJFAROVA, KAROL SUTORIS, DOMINIKA SOJÁKOVÁ, RADKA JAROŠÍKOVÁ, MICHAL KAHLE

Diabetes 2023;72(Supplement_1):511-P

https://doi.org/10.2337/db23-511-P

Published: 20 June 2023

View article titled, 511-P: Is It Reasonable to Treat Infected Diabetic Foot Ulcers by Autologous Cell Therapy in Patients with Severe Ischemia?

Meeting Abstracts

516-P: Lineage Tracing of Vasculogenic Fibroblasts In Vivo and Their Significance in the Rescue of Diabetic Ischemic Tissue

SEDAT KACAR, KANHAIYA SINGH, SUMIT S. VERMA, DIAMOND REESE, MANISHEKHAR KUMAR, SASHWATI ROY, CHANDAN K. SEN

Diabetes 2023;72(Supplement_1):516-P

https://doi.org/10.2337/db23-516-P

Published: 20 June 2023

View article titled, 516-P: Lineage Tracing of Vasculogenic Fibroblasts In Vivo and Their Significance in the Rescue of Diabetic Ischemic Tissue

Meeting Abstracts

510-P: Tissue Nanotransfection–Based Endothelial-Targeted Epigenetic Gene Editing In Vivo to Rescue Diabetic Ischemic Wounds

SUMIT S. VERMA, SEDAT KACAR, SURYA C. GNYAWALI, LEILA S. FEHME, CHANDAN K. SEN, KANHAIYA SINGH

Diabetes 2023;72(Supplement_1):510-P

https://doi.org/10.2337/db23-510-P

Published: 20 June 2023

View article titled, 510-P: Tissue Nanotransfection–Based Endothelial-Targeted Epigenetic Gene Editing In Vivo to Rescue Diabetic Ischemic Wounds

Journal Articles

Critical Role for Macrophages in the Developmental Programming of Pancreatic β-Cell Area in Offspring of Hypertensive Pregnancies

Kate M. Root, Brian Akhaphong, Melissa A. Cedars, Alexa M. Molin, Margaretta E. Huchthausen, Connor F. Laule, Ronald R. Regal, Emilyn U. Alejandro, Jean F. Regal

Diabetes 2022;71(12):2597–2611

https://doi.org/10.2337/db22-0404

Published: 20 September 2022

View article titled, Critical Role for Macrophages in the Developmental Programming of Pancreatic β-Cell Area in Offspring of Hypertensive Pregnancies

Journal Articles

Endothelial Phospholipase Cγ2 Improves Outcomes of Diabetic Ischemic Limb Rescue Following VEGF Therapy

Diabetes 2022;71(5):1149–1165

https://doi.org/10.2337/db21-0830

Published: 22 February 2022

View article titled, Endothelial Phospholipase Cγ2 Improves Outcomes of Diabetic Ischemic Limb Rescue Following VEGF Therapy

Journal Articles

Activation of HIF1α Rescues the Hypoxic Response and Reverses Metabolic Dysfunction in the Diabetic Heart

Maria da Luz Sousa Fialho, Ujang Purnama, Kaitlyn M.J.H. Dennis, Claudia N. Montes Aparicio, Marcos Castro-Guarda, Emmanuelle Massourides, Damian J. Tyler, Carolyn A. Carr, Lisa C. Heather

Diabetes 2021;70(11):2518–2531

https://doi.org/10.2337/db21-0398

Published: 15 September 2021

View article titled, Activation of HIF1α Rescues the Hypoxic Response and Reverses Metabolic Dysfunction in the Diabetic Heart

Journal Articles

Heal Thyself: SGLT2 Inhibition Limits Regenerative Cell Exhaustion and Heals Damaged Vessels

David A. Hess, Daniella C. Terenzi, Subodh Verma

Diabetes 2021;70(8):1620–1622

https://doi.org/10.2337/dbi21-0025

Published: 13 August 2021

View article titled, Heal Thyself: SGLT2 Inhibition Limits Regenerative Cell Exhaustion and Heals Damaged Vessels

Journal Articles

CEPT1-Mediated Phospholipogenesis Regulates Endothelial Cell Function and Ischemia-Induced Angiogenesis Through PPARα

Mohamed A. Zayed, Xiaohua Jin, Chao Yang, Larisa Belaygorod, Connor Engel, Kshitij Desai, Nikolai Harroun, Omar Saffaf, Bruce W. Patterson, Fong-Fu Hsu, Clay F. Semenkovich

Diabetes 2021;70(2):549–561

https://doi.org/10.2337/db20-0635

Published: 19 December 2020

View article titled, CEPT1-Mediated Phospholipogenesis Regulates Endothelial Cell Function and Ischemia-Induced Angiogenesis Through PPARα

Meeting Abstracts

18-LB: Increased Acidosis and Free-Radical Production Causes Recurrent Hypoglycemia–Induced Increase in Post-ischemic ER Stress in Treated Diabetic Rats

ASHISH K. REHNI, SUNJOO CHO, KUNJAN R. DAVE

Diabetes 2020;69(Supplement_1):18-LB

https://doi.org/10.2337/db20-18-LB

Published: 01 June 2020

View article titled, 18-LB: Increased Acidosis and Free-Radical Production Causes Recurrent Hypoglycemia–Induced Increase in Post-ischemic ER Stress in Treated Diabetic Rats

Meeting Abstracts

600-P: Single-Cell RNA Sequencing Identifies Novel Molecular Targets of Endothelial MicroRNA-200b in Diabetic and Ischemic Wounds

KANHAIYA SINGH, EDWARD HERNANDEZ, MANISHEKHAR KUMAR, YASHIKA RUSTAGI, SUJIT K. MOHANTY, AHMED S. ABOUHASHEM, SAVITA KHANNA, SASHWATI ROY, CHANDAN K. SEN

Diabetes 2020;69(Supplement_1):600-P

https://doi.org/10.2337/db20-600-P

Published: 01 June 2020

View article titled, 600-P: Single-Cell RNA Sequencing Identifies Novel Molecular Targets of Endothelial MicroRNA-200b in Diabetic and Ischemic Wounds

Meeting Abstracts

597-P: Prolonged Therapeutic Effects of Photoactivated Adipose-Derived Stem Cells following Diabetic Ischemic Injury

XIN FAN, JIANBO WU

Diabetes 2020;69(Supplement_1):597-P

https://doi.org/10.2337/db20-597-P

Published: 01 June 2020

View article titled, 597-P: Prolonged Therapeutic Effects of Photoactivated Adipose-Derived Stem Cells following Diabetic Ischemic Injury

Meeting Abstracts

605-P: Endothelial-Specific Overexpression of Metallothionein Prevents Diabetes Mellitus–Induced Impairment in Ischemia Angiogenesis via Preservation of HIF-1a/SDF-1/VEGF Signaling in Endothelial Progenitor Cells

KAI WANG, XIAOZHEN DAI, JING CHEN, FEIXIA SHEN, KUPPER A. WINTERGERST, PAUL N. EPSTEIN, LU CAI, YI TAN

Diabetes 2020;69(Supplement_1):605-P

https://doi.org/10.2337/db20-605-P

Published: 01 June 2020

View article titled, 605-P: Endothelial-Specific Overexpression of Metallothionein Prevents Diabetes Mellitus–Induced Impairment in Ischemia Angiogenesis via Preservation of HIF-1a/SDF-1/VEGF Signaling in Endothelial Progenitor Cells

Meeting Abstracts

2225-PUB: Direct Actions of the Dual SGLT1/2 Inhibitor Sotagliflozin on Functional Recovery following Global Ischemia in Diabetic and Healthy Mouse Hearts

EMILY S. DOREY, BROOKE COTTER, THOMAS P. MULLINS, MELISSA E. REICHELT, LINDA A. GALLO

Diabetes 2020;69(Supplement_1):2225-PUB

https://doi.org/10.2337/db20-2225-PUB

Published: 01 June 2020

View article titled, 2225-PUB: Direct Actions of the Dual SGLT1/2 Inhibitor Sotagliflozin on Functional Recovery following Global Ischemia in Diabetic and Healthy Mouse Hearts

Journal Articles

Endothelial Overexpression of Metallothionein Prevents Diabetes-Induced Impairment in Ischemia Angiogenesis Through Preservation of HIF-1α/SDF-1/VEGF Signaling in Endothelial Progenitor Cells

Diabetes 2020;69(8):1779–1792

https://doi.org/10.2337/db19-0829

Published: 13 May 2020

View article titled, Endothelial Overexpression of Metallothionein Prevents Diabetes-Induced Impairment in Ischemia Angiogenesis Through Preservation of HIF-1α/SDF-1/VEGF Signaling in Endothelial Progenitor Cells

Meeting Abstracts

405-P: Transcription Factor Tcf21 Regulates Fibrosis in Ischemic or Hyperglycemic State

YUSUKE BABA, YOSHIRO MAEZAWA, NAOMICHI KONDOU, YOSHIO KOBAYASHI, KOUTARO YOKOTE

Diabetes 2019;68(Supplement_1):405-P

https://doi.org/10.2337/db19-405-P

Published: 01 June 2019

View article titled, 405-P: Transcription Factor Tcf21 Regulates Fibrosis in Ischemic or Hyperglycemic State

Meeting Abstracts

425-P: Inhibition of miR-181c Rescues Diabetes-Impaired Angiogenesis

EMMA SOLLY, SAMUEL T. HOURIGAN, JOCELYNE MULANGALA, PETER J. PSALTIS, BELINDA DI BARTOLO, MARTIN NG, STEPHEN NICHOLLS, CHRISTINA BURSILL, JOANNE T.M. TAN

Diabetes 2019;68(Supplement_1):425-P

https://doi.org/10.2337/db19-425-P

Published: 01 June 2019

View article titled, 425-P: Inhibition of miR-181c Rescues Diabetes-Impaired Angiogenesis

Meeting Abstracts

292-OR: Renin-Angiotensin System Inhibition, Cardiorespiratory Fitness, and Mortality Risk in Diabetic Patients

PETER KOKKINOS, JONATHAN N. MYERS, LABROS SIDOSSIS, CHARLES FASELIS, PUNEET NARAYAN, ERIC NYLEN, XUEMEI SUI, HANS MOORE, PAMELA KARASIK

Diabetes 2019;68(Supplement_1):292-OR

https://doi.org/10.2337/db19-292-OR

Published: 01 June 2019

View article titled, 292-OR: Renin-Angiotensin System Inhibition, Cardiorespiratory Fitness, and Mortality Risk in Diabetic Patients

Meeting Abstracts

45-OR: The Role of the Angiopoietin-Tie2 Pathway in Microvascular Complications of Diabetes Mellitus

VICTOR H. GONZALEZ

Diabetes 2019;68(Supplement_1):45-OR

https://doi.org/10.2337/db19-45-OR

Published: 01 June 2019

View article titled, 45-OR: The Role of the Angiopoietin-Tie2 Pathway in Microvascular Complications of Diabetes Mellitus

Meeting Abstracts

1936-P: Muscle Ischemia Impairs Insulin-Mediated Microvascular Recruitment

NASUI WANG, ZHENQI LIU

Diabetes 2019;68(Supplement_1):1936-P

https://doi.org/10.2337/db19-1936-P

Published: 01 June 2019

View article titled, 1936-P: Muscle Ischemia Impairs Insulin-Mediated Microvascular Recruitment

NARROW

512-P: Single-Cell RNA-Sequencing Identifies Novel Molecular Targets of Endothelial MicroRNA-200b in the Diabetic Ischemic Wound

511-P: Is It Reasonable to Treat Infected Diabetic Foot Ulcers by Autologous Cell Therapy in Patients with Severe Ischemia?

516-P: Lineage Tracing of Vasculogenic Fibroblasts In Vivo and Their Significance in the Rescue of Diabetic Ischemic Tissue

510-P: Tissue Nanotransfection–Based Endothelial-Targeted Epigenetic Gene Editing In Vivo to Rescue Diabetic Ischemic Wounds

Critical Role for Macrophages in the Developmental Programming of Pancreatic β-Cell Area in Offspring of Hypertensive Pregnancies

Endothelial Phospholipase Cγ2 Improves Outcomes of Diabetic Ischemic Limb Rescue Following VEGF Therapy

Activation of HIF1α Rescues the Hypoxic Response and Reverses Metabolic Dysfunction in the Diabetic Heart

Heal Thyself: SGLT2 Inhibition Limits Regenerative Cell Exhaustion and Heals Damaged Vessels

CEPT1-Mediated Phospholipogenesis Regulates Endothelial Cell Function and Ischemia-Induced Angiogenesis Through PPARα

18-LB: Increased Acidosis and Free-Radical Production Causes Recurrent Hypoglycemia–Induced Increase in Post-ischemic ER Stress in Treated Diabetic Rats

600-P: Single-Cell RNA Sequencing Identifies Novel Molecular Targets of Endothelial MicroRNA-200b in Diabetic and Ischemic Wounds

597-P: Prolonged Therapeutic Effects of Photoactivated Adipose-Derived Stem Cells following Diabetic Ischemic Injury

605-P: Endothelial-Specific Overexpression of Metallothionein Prevents Diabetes Mellitus–Induced Impairment in Ischemia Angiogenesis via Preservation of HIF-1a/SDF-1/VEGF Signaling in Endothelial Progenitor Cells

2225-PUB: Direct Actions of the Dual SGLT1/2 Inhibitor Sotagliflozin on Functional Recovery following Global Ischemia in Diabetic and Healthy Mouse Hearts

Endothelial Overexpression of Metallothionein Prevents Diabetes-Induced Impairment in Ischemia Angiogenesis Through Preservation of HIF-1α/SDF-1/VEGF Signaling in Endothelial Progenitor Cells

405-P: Transcription Factor Tcf21 Regulates Fibrosis in Ischemic or Hyperglycemic State

425-P: Inhibition of miR-181c Rescues Diabetes-Impaired Angiogenesis

292-OR: Renin-Angiotensin System Inhibition, Cardiorespiratory Fitness, and Mortality Risk in Diabetic Patients

45-OR: The Role of the Angiopoietin-Tie2 Pathway in Microvascular Complications of Diabetes Mellitus

1936-P: Muscle Ischemia Impairs Insulin-Mediated Microvascular Recruitment

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