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Meeting Abstracts

232-LB: Transcriptional Regulation of Adipocyte Insulin and Inflammatory Signaling by Early B-Cell Factor-1 (Ebf1)

ALEX GUTIERREZ, YADIRA MARTINEZ, KIMBERLY IBARRA, ZACHARY BAILEY, MICHAEL GRIFFIN

Diabetes 2023;72(Supplement_1):232-LB

https://doi.org/10.2337/db23-232-LB

Published: 20 June 2023

View article titled, 232-LB: Transcriptional Regulation of Adipocyte Insulin and Inflammatory Signaling by Early B-Cell Factor-1 (Ebf1)

Meeting Abstracts

225-LB: Reciprocal Regulatory Interactions of Adipocytes and B Lymphocytes

JOSEPH W. BREWER, MARY K. ALLMAN, STEVEN R. CARROLL, SARAH GRANGER, ALEXANDER HALL, KEELEY POWNALL, JOSHUA QUINTANA, NANCY ARELLANO RANGEL, JADE THOMAS, ROBERT L. JUDD

Diabetes 2023;72(Supplement_1):225-LB

https://doi.org/10.2337/db23-225-LB

Published: 20 June 2023

View article titled, 225-LB: Reciprocal Regulatory Interactions of Adipocytes and B Lymphocytes

Journal Articles

Reduced Follicular Regulatory T Cells in Spleen and Pancreatic Lymph Nodes of Patients With Type 1 Diabetes

Diabetes 2021;70(12):2892–2902

https://doi.org/10.2337/db21-0091

Published: 07 October 2021

View article titled, Reduced Follicular Regulatory T Cells in Spleen and Pancreatic Lymph Nodes of Patients With Type 1 Diabetes

Journal Articles

Uncovering Pathways to Personalized Therapies in Type 1 Diabetes

Peter S. Linsley, Carla J. Greenbaum, Gerald T. Nepom

Diabetes 2021;70(4):831–841

https://doi.org/10.2337/db20-1185

Published: 16 March 2021

View article titled, Uncovering Pathways to Personalized Therapies in Type 1 Diabetes

Journal Articles

Natural Protection From Type 1 Diabetes in NOD Mice Is Characterized by a Unique Pancreatic Islet Phenotype

Joanne Boldison, Terri C. Thayer, Joanne Davies, F. Susan Wong

Diabetes 2021;70(4):955–965

https://doi.org/10.2337/db20-0945

Published: 02 February 2021

View article titled, Natural Protection From Type 1 Diabetes in NOD Mice Is Characterized by a Unique Pancreatic Islet Phenotype

Journal Articles

TLR9 Deficiency in B Cells Promotes Immune Tolerance via Interleukin-10 in a Type 1 Diabetes Mouse Model

Sha Sha, James A. Pearson, Jian Peng, Youjia Hu, Juan Huang, Yanpeng Xing, Luyao Zhang, Ying Zhu, Hongyu Zhao, F. Susan Wong, Li Chen, Li Wen

Diabetes 2021;70(2):504–515

https://doi.org/10.2337/db20-0373

Published: 05 November 2020

View article titled, TLR9 Deficiency in B Cells Promotes Immune Tolerance via Interleukin-10 in a Type 1 Diabetes Mouse Model

Meeting Abstracts

250-LB: Affinity Purification and Identification of Unique, Shared, Anti-IA-2 B-Cell Clonotypes: A Proteomic Approach to Understanding Pathophysiological Mechanisms Underpinning Humoral Autoimmunity in Type 1 Diabetes

THILINI MENDIS, JING JING WANG, MASSIMO PIETROPAOLO, MICHAEL W. JACKSON

Diabetes 2019;68(Supplement_1):250-LB

https://doi.org/10.2337/db19-250-LB

Published: 01 June 2019

View article titled, 250-LB: Affinity Purification and Identification of Unique, Shared, Anti-IA-2 B-Cell Clonotypes: A Proteomic Approach to Understanding Pathophysiological Mechanisms Underpinning Humoral Autoimmunity in Type 1 Diabetes

Journal Articles

T-Cell–Specific PTPN2 Deficiency in NOD Mice Accelerates the Development of Type 1 Diabetes and Autoimmune Comorbidities

Florian Wiede, Thomas C. Brodnicki, Pei Kee Goh, Yew A. Leong, Gareth W. Jones, Di Yu, Alan G. Baxter, Simon A. Jones, Thomas W.H. Kay, Tony Tiganis

Diabetes 2019;68(6):1251–1266

https://doi.org/10.2337/db18-1362

Published: 01 April 2019

View article titled, T-Cell–Specific PTPN2 Deficiency in NOD Mice Accelerates the Development of Type 1 Diabetes and Autoimmune Comorbidities

Includes: Supplementary data

Journal Articles

Dynamic Immune Phenotypes of B and T Helper Cells Mark Distinct Stages of T1D Progression

Tania Habib, S. Alice Long, Peter L. Samuels, Archana Brahmandam, Megan Tatum, Andrew Funk, Anne M. Hocking, Karen Cerosaletti, Michael T. Mason, Elizabeth Whalen, David J. Rawlings, Carla Greenbaum, Jane H. Buckner, the Type 1 Diabetes TrialNet Study Group

Diabetes 2019;68(6):1240–1250

https://doi.org/10.2337/db18-1081

Published: 20 March 2019

View article titled, Dynamic Immune Phenotypes of B and T Helper Cells Mark Distinct Stages of T1D Progression

Includes: Supplementary data

Journal Articles

Healthy Donor Polyclonal IgMs Diminish B-Lymphocyte Autoreactivity, Enhance Regulatory T-Cell Generation, and Reverse Type 1 Diabetes in NOD Mice

Christopher S. Wilson, Preeti Chhabra, Andrew F. Marshall, Caleigh V. Morr, Blair T. Stocks, Emilee M. Hoopes, Rachel H. Bonami, Greg Poffenberger, Kenneth L. Brayman, Daniel J. Moore

Diabetes 2018;67(11):2349–2360

https://doi.org/10.2337/db18-0456

Published: 21 August 2018

View article titled, Healthy Donor Polyclonal IgMs Diminish B-Lymphocyte Autoreactivity, Enhance Regulatory T-Cell Generation, and Reverse Type 1 Diabetes in NOD Mice

Includes: Supplementary data

Journal Articles

Loss of OcaB Prevents Age-Induced Fat Accretion and Insulin Resistance by Altering B-Lymphocyte Transition and Promoting Energy Expenditure

Diabetes 2018;67(7):1285–1296

https://doi.org/10.2337/db17-0558

Published: 01 March 2018

View article titled, Loss of OcaB Prevents Age-Induced Fat Accretion and Insulin Resistance by Altering B-Lymphocyte Transition and Promoting Energy Expenditure

Includes: Supplementary data

Journal Articles

Loss of B-Cell Anergy in Type 1 Diabetes Is Associated With High-Risk HLA and Non-HLA Disease Susceptibility Alleles

Mia J. Smith, Marynette Rihanek, Clive Wasserfall, Clayton E. Mathews, Mark A. Atkinson, Peter A. Gottlieb, John C. Cambier

Diabetes 2018;67(4):697–703

https://doi.org/10.2337/db17-0937

Published: 17 January 2018

View article titled, Loss of B-Cell Anergy in Type 1 Diabetes Is Associated With High-Risk HLA and Non-HLA Disease Susceptibility Alleles

Includes: Supplementary data

Journal Articles

Follicular T Helper Cells: A New Marker of Type 1 Diabetes Risk?

Frank Heuts, Natalie M. Edner, Lucy S.K. Walker

Diabetes 2017;66(2):258–260

https://doi.org/10.2337/dbi16-0062

Published: 13 January 2017

View article titled, Follicular T Helper Cells: A New Marker of Type 1 Diabetes Risk?

Journal Articles

Circulating CXCR5⁺PD-1⁺ICOS⁺ Follicular T Helper Cells Are Increased Close to the Diagnosis of Type 1 Diabetes in Children With Multiple Autoantibodies

Tyyne Viisanen, Emmi-Leena Ihantola, Kirsti Näntö-Salonen, Heikki Hyöty, Noora Nurminen, Jenni Selvenius, Auni Juutilainen, Leena Moilanen, Jussi Pihlajamäki, Riitta Veijola, Jorma Toppari, Mikael Knip, Jorma Ilonen, Tuure Kinnunen

Diabetes 2017;66(2):437–447

https://doi.org/10.2337/db16-0714

Published: 10 October 2016

View article titled, Circulating CXCR5+PD-1+ICOS+ Follicular T Helper Cells Are Increased Close to the Diagnosis of Type 1 Diabetes in Children With Multiple Autoantibodies

Includes: Supplementary data

Journal Articles

New Players in the Field of T1D: Anti-Peripherin B Lymphocytes

Peggy L. Kendall

Diabetes 2016;65(7):1794–1796

https://doi.org/10.2337/dbi16-0017

Published: 13 June 2016

View article titled, New Players in the Field of T1D: Anti-Peripherin B Lymphocytes

Journal Articles

Delving Into the Type 1 Diabetic Islet: Evidence That B-Cell Infiltration of Islets Is Linked to Local Hyperimmunity and Accelerated Progression to Disease

Michael R. Christie

Diabetes 2016;65(5):1146–1148

https://doi.org/10.2337/dbi16-0008

Published: 15 April 2016

View article titled, Delving Into the Type 1 Diabetic Islet: Evidence That B-Cell Infiltration of Islets Is Linked to Local Hyperimmunity and Accelerated Progression to Disease

Journal Articles

B-Lymphocytes Expressing an Ig Specificity Recognizing the Pancreatic β-Cell Autoantigen Peripherin Are Potent Contributors to Type 1 Diabetes Development in NOD Mice

Caroline M. Leeth, Jeremy Racine, Harold D. Chapman, Berta Arpa, Jorge Carrillo, Jorge Carrascal, Qiming Wang, Jeremy Ratiu, Leire Egia-Mendikute, Estela Rosell-Mases, Thomas Stratmann, Joan Verdaguer, David V. Serreze

Diabetes 2016;65(7):1977–1987

https://doi.org/10.2337/db15-1606

Published: 09 March 2016

View article titled, B-Lymphocytes Expressing an Ig Specificity Recognizing the Pancreatic β-Cell Autoantigen Peripherin Are Potent Contributors to Type 1 Diabetes Development in NOD Mice

Includes: Supplementary data

Journal Articles

Differential Insulitic Profiles Determine the Extent of β-Cell Destruction and the Age at Onset of Type 1 Diabetes

Pia Leete, Abby Willcox, Lars Krogvold, Knut Dahl-Jørgensen, Alan K. Foulis, Sarah J. Richardson, Noel G. Morgan

Diabetes 2016;65(5):1362–1369

https://doi.org/10.2337/db15-1615

Published: 08 February 2016

View article titled, Differential Insulitic Profiles Determine the Extent of β-Cell Destruction and the Age at Onset of Type 1 Diabetes

Includes: Supplementary data

Journal Articles

Are Obesity-Related Insulin Resistance and Type 2 Diabetes Autoimmune Diseases?

Sue Tsai, Xavier Clemente-Casares, Xavier S. Revelo, Shawn Winer, Daniel A. Winer

Diabetes 2015;64(6):1886–1897

https://doi.org/10.2337/db14-1488

Published: 16 May 2015

View article titled, Are Obesity-Related Insulin Resistance and Type 2 Diabetes Autoimmune Diseases?

Journal Articles

Loss of Anergic B Cells in Prediabetic and New-Onset Type 1 Diabetic Patients

Mia J. Smith, Thomas A. Packard, Shannon K. O’Neill, Carole J. Henry Dunand, Min Huang, Lisa Fitzgerald-Miller, Daniel Stowell, Rochelle M. Hinman, Patrick C. Wilson, Peter A. Gottlieb, John C. Cambier

Diabetes 2015;64(5):1703–1712

https://doi.org/10.2337/db13-1798

Published: 18 December 2014

View article titled, Loss of Anergic B Cells in Prediabetic and New-Onset Type 1 Diabetic Patients

NARROW

232-LB: Transcriptional Regulation of Adipocyte Insulin and Inflammatory Signaling by Early B-Cell Factor-1 (Ebf1)

225-LB: Reciprocal Regulatory Interactions of Adipocytes and B Lymphocytes

Reduced Follicular Regulatory T Cells in Spleen and Pancreatic Lymph Nodes of Patients With Type 1 Diabetes

Uncovering Pathways to Personalized Therapies in Type 1 Diabetes

Natural Protection From Type 1 Diabetes in NOD Mice Is Characterized by a Unique Pancreatic Islet Phenotype

TLR9 Deficiency in B Cells Promotes Immune Tolerance via Interleukin-10 in a Type 1 Diabetes Mouse Model

250-LB: Affinity Purification and Identification of Unique, Shared, Anti-IA-2 B-Cell Clonotypes: A Proteomic Approach to Understanding Pathophysiological Mechanisms Underpinning Humoral Autoimmunity in Type 1 Diabetes

T-Cell–Specific PTPN2 Deficiency in NOD Mice Accelerates the Development of Type 1 Diabetes and Autoimmune Comorbidities

Dynamic Immune Phenotypes of B and T Helper Cells Mark Distinct Stages of T1D Progression

Healthy Donor Polyclonal IgMs Diminish B-Lymphocyte Autoreactivity, Enhance Regulatory T-Cell Generation, and Reverse Type 1 Diabetes in NOD Mice

Loss of OcaB Prevents Age-Induced Fat Accretion and Insulin Resistance by Altering B-Lymphocyte Transition and Promoting Energy Expenditure

Loss of B-Cell Anergy in Type 1 Diabetes Is Associated With High-Risk HLA and Non-HLA Disease Susceptibility Alleles

Follicular T Helper Cells: A New Marker of Type 1 Diabetes Risk?

Circulating CXCR5⁺PD-1⁺ICOS⁺ Follicular T Helper Cells Are Increased Close to the Diagnosis of Type 1 Diabetes in Children With Multiple Autoantibodies

New Players in the Field of T1D: Anti-Peripherin B Lymphocytes

Delving Into the Type 1 Diabetic Islet: Evidence That B-Cell Infiltration of Islets Is Linked to Local Hyperimmunity and Accelerated Progression to Disease

B-Lymphocytes Expressing an Ig Specificity Recognizing the Pancreatic β-Cell Autoantigen Peripherin Are Potent Contributors to Type 1 Diabetes Development in NOD Mice

Differential Insulitic Profiles Determine the Extent of β-Cell Destruction and the Age at Onset of Type 1 Diabetes

Are Obesity-Related Insulin Resistance and Type 2 Diabetes Autoimmune Diseases?

Loss of Anergic B Cells in Prediabetic and New-Onset Type 1 Diabetic Patients

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