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March 2023
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Close ModalOn the cover: Gastric bypass surgery. Colored frontal X-rays of a 48-year-old patient with obesity showing the upper gastrointestinal tract 6 months after gastric bypass surgery. A gastric bypass reduces the size of the stomach, making the patient feel full after eating less food. Credit: Zephyr/Science Source. For more information, see www.sciencesource.com.
Authors are invited to submit images for use on the cover of Diabetes. Black and white or color photographic or photomicrographic images are acceptable. Cover image submission and selection is completely independent of article submission and the peer-review process.
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ISSN 0012-1797
EISSN 1939-327X
In This Issue
In This Issue of Diabetes
Topics:
bariatric surgery
,
dna methylation
,
epigenome-wide association study
,
fat, subcutaneous
,
hormones
Diabetes February 2023, Vol.72, 311-312. doi:https://doi.org/10.2337/db23-ti03
Commentary
Cardiac Microvascular Dysfunction and Cardiomyopathy in Diabetes: Is Ferroptosis a Therapeutic Target?
Topics:
cardiomyopathy
,
ferroptosis
Diabetes February 2023, Vol.72, 313-315. doi:https://doi.org/10.2337/dbi22-0036
Metabolism
Relationship Between a Sedentary Lifestyle and Adipose Insulin Resistance
Topics:
adipocytes
,
fatty acids
,
insulin
,
insulin resistance
,
lack of exercise
Diabetes November 2022, Vol.72, 316-325. doi:https://doi.org/10.2337/db22-0612
Rhamnose Displays an Anti-Obesity Effect Through Stimulation of Adipose Dopamine Receptors and Thermogenesis
Sihan Lv; Tingting Hu; Ru Zhang; Yue Zhou; Wenjing Yu; Zelin Wang; Changjie Shi; Junjiang Lian; Shichao Huang; Gang Pei; Bing Luan
Topics:
obesity
,
rhamnose
,
thermogenesis
,
dopamine receptors
,
adipocytes
Diabetes December 2022, Vol.72, 326-335. doi:https://doi.org/10.2337/db22-0552
The Importance of Endogenously Secreted GLP-1 and GIP for Postprandial Glucose Tolerance and β-Cell Function After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy Surgery
Morten Hindsø; Nora Hedbäck; Maria S. Svane; Andreas Møller; Christoffer Martinussen; Nils B. Jørgensen; Carsten Dirksen; Lærke S. Gasbjerg; Viggo B. Kristiansen; Bolette Hartmann; Mette M. Rosenkilde; Jens J. Holst; Sten Madsbad; Kirstine N. Bojsen-Møller
Topics:
glucagon-like peptide 1
,
glucose
,
postprandial period
,
surgical procedures, operative
,
glucagon
Diabetes December 2022, Vol.72, 336-347. doi:https://doi.org/10.2337/db22-0568
High-Fat Diet–Induced DeSUMOylation of E4BP4 Promotes Lipid Droplet Biogenesis and Liver Steatosis in Mice
Sujuan Wang; Meichan Yang; Pei Li; Julian Sit; Audrey Wong; Kyle Rodrigues; Daniel Lank; Deqiang Zhang; Kezhong Zhang; Lei Yin; Xin Tong
Topics:
fatty liver
,
hepatocytes
,
liver
,
mice
,
diet, high-fat
Diabetes December 2022, Vol.72, 348-361. doi:https://doi.org/10.2337/db22-0332
Lower Hepatic Fat Is Associated With Improved Insulin Secretion in a High-Risk Prediabetes Subphenotype During Lifestyle Intervention
Robert Wagner; Martin Heni; Konstantinos Kantartzis; Arvid Sandforth; Jürgen Machann; Fritz Schick; Andreas Peter; Louise Fritsche; Julia Szendrödi; Andreas F.H. Pfeiffer; Annette Schürmann; Matthias Blüher; Hans Hauner; Jochen Seissler; Stefan Bornstein; Michael Roden; Norbert Stefan; Andreas L. Birkenfeld; Morris F. White; Hans-Ulrich Häring; Andreas Fritsche
Topics:
insulin secretion
,
life style
,
liver
,
prediabetes
,
insulin sensitivity
Diabetes December 2022, Vol.72, 362-366. doi:https://doi.org/10.2337/db22-0441
Obesity Studies
Adipocyte-Secreted IL-6 Sensitizes Macrophages to IL-4 Signaling
Danny Luan; Benyamin Dadpey; Jessica Zaid; Pania E. Bridge-Comer; Julia H. DeLuca; Wenmin Xia; Joshua Castle; Shannon M. Reilly
Topics:
adipocytes
,
interleukin-4
,
interleukin-6
,
macrophages
,
signal transduction
Diabetes November 2022, Vol.72, 367-374. doi:https://doi.org/10.2337/db22-0444
miR-210-3p Promotes Obesity-Induced Adipose Tissue Inflammation and Insulin Resistance by Targeting SOCS1-Mediated NF-κB Pathway
Debarun Patra; Soumyajit Roy; Leena Arora; Shaheen Wasil Kabeer; Satpal Singh; Upalabdha Dey; Dipanjan Banerjee; Archana Sinha; Suman Dasgupta; Kulbhushan Tikoo; Aditya Kumar; Durba Pal
Topics:
inflammation
,
obesity
,
socs1 gene
,
suppressor of cytokine signaling 1 protein
,
insulin resistance
Diabetes December 2022, Vol.72, 375-388. doi:https://doi.org/10.2337/db22-0284
Pharmacology and Therapeutics
Isorhapontigenin Attenuates Cardiac Microvascular Injury in Diabetes via the Inhibition of Mitochondria-Associated Ferroptosis Through PRDX2-MFN2-ACSL4 Pathways
Yuqiong Chen; Su Li; Ming Yin; Yafei Li; Chao Chen; Jun Zhang; Kangyun Sun; Xiangqing Kong; Zhangwei Chen; Juying Qian
Topics:
endothelium
,
ferroptosis
,
international organization for standardization
,
iron
,
mfn2 gene
Diabetes November 2022, Vol.72, 389-404. doi:https://doi.org/10.2337/db22-0553
DPP-4 Inhibitor and Sulfonylurea Differentially Reverse Type 2 Diabetes–Induced Blood–Brain Barrier Leakage and Normalize Capillary Pericyte Coverage
Osama F. Elabi; Dimitra Karampatsi; Ellen Vercalsteren; Grazyna Lietzau; Thomas Nyström; Thomas Klein; Vladimer Darsalia; Cesare Patrone; Gesine Paul
Topics:
diabetes mellitus, type 2
,
pericytes
,
antidiabetics
,
diet
,
brain
Diabetes November 2022, Vol.72, 405-414. doi:https://doi.org/10.2337/db22-0674
GENETICS / GENOMES / PROTEOMICS / METABOLOMICS
Cross-Ancestry DNA Methylation Marks of Insulin Resistance in Pregnancy: An Integrative Epigenome-Wide Association Study
Nicolas Fragoso-Bargas; Hannah R. Elliott; Sindre Lee-Ødegård; Julia O. Opsahl; Line Sletner; Anne Karen Jenum; Christian A. Drevon; Elisabeth Qvigstad; Gunn-Helen Moen; Kåre I. Birkeland; Rashmi B. Prasad; Christine Sommer
Topics:
dna methylation
,
epigenome-wide association study
,
insulin resistance
,
phenotype
,
mediation analysis
Diabetes December 2022, Vol.72, 415-426. doi:https://doi.org/10.2337/db22-0504
Issues and Events
Issues and Events
Topics:
anemia of chronic renal failure
,
diabetes mellitus, type 1
,
eye care
,
overweight
,
podcasts
Diabetes February 2023, Vol.72, 427. doi:https://doi.org/10.2337/db23-ie03
