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Journal Articles

Effect of Empagliflozin on Endothelial Function in Patients With Type 2 Diabetes and Cardiovascular Disease: Results from the Multicenter, Randomized, Placebo-Controlled, Double-Blind EMBLEM Trial

Atsushi Tanaka, Michio Shimabukuro, Noritaka Machii, Hiroki Teragawa, Yosuke Okada, Kosuke R. Shima, Toshinari Takamura, Isao Taguchi, Itaru Hisauchi, Shigeru Toyoda, Yasushi Matsuzawa, Hirofumi Tomiyama, Minako Yamaoka-Tojo, Hisako Yoshida, Yasunori Sato, Yumi Ikehara, Shinichiro Ueda, Yukihito Higashi, Koichi Node, EMBLEM Investigators, Junya Ako, Hirohisa Amano, Teruo Inoue, Hideaki Jinnouchi, Atsushi Kawaguchi, Yoshiyuki Kawano, Kazuo Kimura, Akira Kurozumi, Takaaki Kusumoto, Tatsuya Maruhashi, Hirofumi Misu, Katsunori Nakamura, Manabu Narisawa, Junya Nishi, Tsuguhito Ota, Jun-ichi Oyama, Masashi Sakuma, Kazuki Shiina, Seigo Sugiyama, Kunihiro Suzuki, Naohiko Takahashi, Yasuhiko Takemoto, Yumie Takeshita, Hiroshi Tamaki, Akira Tamura, Kenichi Tanaka, Takafumi Toita, Keiichi Torimoto, Hiroki Uehara, Fumi Uemura, Ken Yamakawa, Kunio Yufu
Journal: Diabetes Care
Diabetes Care 2019;42(10):e159–e161
https://doi.org/10.2337/dc19-1177
Published: 12 September 2019
View article titled, Effect of Empagliflozin on Endothelial Function in Patients With Type 2 Diabetes and Cardiovascular Disease: Results from the Multicenter, Randomized, Placebo-Controlled, Double-Blind EMBLEM Trial
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Includes: Supplementary data
Journal Articles

Effects of Metformin Therapy on Coronary Endothelial Dysfunction in Patients With Prediabetes With Stable Angina and Nonobstructive Coronary Artery Stenosis: The CODYCE Multicenter Prospective Study

Celestino Sardu, Pasquale Paolisso, Cosimo Sacra, Ciro Mauro, Fabio Minicucci, Michele Portoghese, Maria Rosaria Rizzo, Michelangela Barbieri, Ferdinando Carlo Sasso, Nunzia D’Onofrio, Maria Luisa Balestrieri, Paolo Calabrò, Giuseppe Paolisso, Raffaele Marfella
Journal: Diabetes Care
Diabetes Care 2019;42(10):1946–1955
https://doi.org/10.2337/dc18-2356
Published: 22 February 2019
View article titled, Effects of Metformin Therapy on Coronary Endothelial Dysfunction in Patients With Prediabetes With Stable Angina and Nonobstructive Coronary Artery Stenosis: The CODYCE Multicenter Prospective Study
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Journal Articles

Ratio of Serum Levels of AGEs to Soluble Form of RAGE Is a Predictor of Endothelial Function

Masato Kajikawa, Ayumu Nakashima, Noritaka Fujimura, Tatsuya Maruhashi, Yumiko Iwamoto, Akimichi Iwamoto, Takeshi Matsumoto, Nozomu Oda, Takayuki Hidaka, Yasuki Kihara, Kazuaki Chayama, Chikara Goto, Yoshiki Aibara, Kensuke Noma, Masayoshi Takeuchi, Takanori Matsui, Sho-ichi Yamagishi, Yukihito Higashi
Journal: Diabetes Care
Diabetes Care 2015;38(1):119–125
https://doi.org/10.2337/dc14-1435
Published: 21 October 2014
View article titled, Ratio of Serum Levels of AGEs to Soluble Form of RAGE Is a Predictor of Endothelial Function
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Includes: Supplementary data
Journal Articles

The Effects of Dipeptidyl Peptidase-4 Inhibition on Microvascular Diabetes Complications

Angelo Avogaro, Gian Paolo Fadini
Journal: Diabetes Care
Diabetes Care 2014;37(10):2884–2894
https://doi.org/10.2337/dc14-0865
Published: 10 September 2014
View article titled, The Effects of Dipeptidyl Peptidase-4 Inhibition on Microvascular Diabetes Complications
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Journal Articles

Targeting Inflammation Using Salsalate in Patients With Type 2 Diabetes: Effects on Flow-Mediated Dilation (TINSAL-FMD)

Allison B. Goldfine, MD, J. Stewart Buck, BS, Cyrus Desouza, MD, Vivian Fonseca, MD, Yii-Der Ida Chen, PHD, Steven E. Shoelson, MD, Kathleen A. Jablonski, PHD, Mark A. Creager, MD, for the TINSAL-FMD (Targeting Inflammation Using Salsalate in Type 2 Diabetes–Flow-Mediated Dilation) Ancillary Study Team
Journal: Diabetes Care
Diabetes Care 2013;36(12):4132–4139
https://doi.org/10.2337/dc13-0859
Published: 13 November 2013
View article titled, Targeting Inflammation Using Salsalate in Patients With Type 2 Diabetes: Effects on Flow-Mediated Dilation (TINSAL-FMD)
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Journal Articles

Glucagon-Like Peptide 1 Reduces Endothelial Dysfunction, Inflammation, and Oxidative Stress Induced by Both Hyperglycemia and Hypoglycemia in Type 1 Diabetes

Antonio Ceriello, MD, Anna Novials, MD, Emilio Ortega, MD, Silvia Canivell, MD, Lucia La Sala, PHD, Gemma Pujadas, PHD, Katherine Esposito, MD, Dario Giugliano, MD, Stefano Genovese, MD
Journal: Diabetes Care
Diabetes Care 2013;36(8):2346–2350
https://doi.org/10.2337/dc12-2469
Published: 11 July 2013
View article titled, Glucagon-Like Peptide 1 Reduces Endothelial Dysfunction, Inflammation, and Oxidative Stress Induced by Both Hyperglycemia and Hypoglycemia in Type 1 Diabetes
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Journal Articles

The Effect of Direct Renin Inhibition Alone and in Combination With ACE Inhibition on Endothelial Function, Arterial Stiffness, and Renal Function in Type 1 Diabetes

David Z.I. Cherney, MD, James W. Scholey, MD, Shan Jiang, BMSC, Ronnie Har, BSC, Vesta Lai, RN, Etienne B. Sochett, MBBCH, Heather N. Reich, MD
Journal: Diabetes Care
Diabetes Care 2012;35(11):2324–2330
https://doi.org/10.2337/dc12-0773
Published: 13 October 2012
View article titled, The Effect of Direct Renin Inhibition Alone and in Combination With ACE Inhibition on Endothelial Function, Arterial Stiffness, and Renal Function in Type 1 Diabetes
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Journal Articles

Effects of Electronegative VLDL on Endothelium Damage in Metabolic Syndrome

Chu-Huang Chen, MD, Jonathan Lu, MD, Shu-Hua Chen, BS, Roger Y. Huang, BS, H. Ramazan Yilmaz, PHD, Jianwen Dong, PHD, MacArthur A. Elayda, MD, Richard A.F. Dixon, PHD, Chao-Yuh Yang, PHD
Journal: Diabetes Care
Diabetes Care 2012;35(3):648–653
https://doi.org/10.2337/dc11-1623
Published: 10 February 2012
View article titled, Effects of Electronegative VLDL on Endothelium Damage in Metabolic Syndrome
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Journal Articles

Vildagliptin Improves Endothelium-Dependent Vasodilatation in Type 2 Diabetes

Pleun C.M. van Poppel, MD, Mihai G. Netea, MD, Paul Smits, MD, Cees J. Tack, MD
Journal: Diabetes Care
Diabetes Care 2011;34(9):2072–2077
https://doi.org/10.2337/dc10-2421
Published: 19 August 2011
View article titled, Vildagliptin Improves Endothelium-Dependent Vasodilatation in Type 2 Diabetes
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Includes: Supplementary data
Journal Articles

Impact of Glycemic and Blood Pressure Variability on Surrogate Measures of Cardiovascular Outcomes in Type 2 Diabetic Patients

Alessandra Di Flaviani, MD, Fabiana Picconi, MD, Paola Di Stefano, PHD, Ilaria Giordani, MD, Ilaria Malandrucco, MD, Paola Maggio, MD, Paola Palazzo, MD, Fabrizio Sgreccia, MD, Carlo Peraldo, MD, Fabrizio Farina, MD, Gaetano Frajese, MD, Simona Frontoni, MD
Journal: Diabetes Care
Diabetes Care 2011;34(7):1605–1609
https://doi.org/10.2337/dc11-0034
Published: 17 June 2011
View article titled, Impact of Glycemic and Blood Pressure Variability on Surrogate Measures of Cardiovascular Outcomes in Type 2 Diabetic Patients
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Journal Articles

Diabetic Retinopathy Is Related to Both Endothelium-Dependent and -Independent Responses of Skin Microvascular Flow

Thanh T. Nguyen, MBBS, Jonathan E. Shaw, MD, Carol Robinson, PHD, Ryo Kawasaki, MD, Jie Jin Wang, PHD, Andreas J. Kreis, MD, Tien Y. Wong, MD
Journal: Diabetes Care
Diabetes Care 2011;34(6):1389–1393
https://doi.org/10.2337/dc10-1985
Published: 20 May 2011
View article titled, Diabetic Retinopathy Is Related to Both Endothelium-Dependent and -Independent Responses of Skin Microvascular Flow
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Includes: Supplementary data
Journal Articles

Endothelial Dysfunction in Diabetes: The role of reparatory mechanisms

Angelo Avogaro, MD, Mattia Albiero, PHD, Lisa Menegazzo, PHD, Saula de Kreutzenberg, MD, Gian Paolo Fadini, MD
Journal: Diabetes Care
Diabetes Care 2011;34(Supplement_2):S285–S290
https://doi.org/10.2337/dc11-s239
Published: 22 April 2011
View article titled, Endothelial Dysfunction in Diabetes: <subtitle>The role of reparatory mechanisms</subtitle>
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Journal Articles

Impaired Endothelial Function in Preadolescent Children With Type 1 Diabetes

Ghufran S. Babar, MD, Hanaa Zidan, MD, Michael E. Widlansky, MD, Emon Das, MD, Raymond G. Hoffmann, PHD, Marwan Daoud, PHD, Ramin Alemzadeh, MD
Journal: Diabetes Care
Diabetes Care 2011;34(3):681–685
https://doi.org/10.2337/dc10-2134
Published: 17 February 2011
View article titled, Impaired Endothelial Function in Preadolescent Children With Type 1 Diabetes
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Journal Articles

The Possible Protective Role of Glucagon-Like Peptide 1 on Endothelium During the Meal and Evidence for an “Endothelial Resistance” to Glucagon-Like Peptide 1 in Diabetes

Antonio Ceriello, MD, Katherine Esposito, MD, Roberto Testa, MD, Anna Rita Bonfigli, PHD, Maurizio Marra, PHD, Dario Giugliano, MD
Journal: Diabetes Care
Diabetes Care 2011;34(3):697–702
https://doi.org/10.2337/dc10-1949
Published: 17 February 2011
View article titled, The Possible Protective Role of Glucagon-Like Peptide 1 on Endothelium During the Meal and Evidence for an “Endothelial Resistance” to Glucagon-Like Peptide 1 in Diabetes
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Journal Articles

Endothelial Markers May Link Kidney Function to Cardiovascular Events in Type 2 Diabetes

Christina Maier, MD, Martin Clodi, MD, Stephanie Neuhold, MD, Michael Resl, MD, Marie Elhenicky, MD, Rudolf Prager, MD, Deddo Moertl, MD, Guido Strunk, PHD, Anton Luger, MD, Joachim Struck, PHD, Richard Pacher, MD, Martin Hülsmann, MD
Journal: Diabetes Care
Diabetes Care 2009;32(10):1890–1895
https://doi.org/10.2337/dc08-2168
Published: 29 June 2009
View article titled, Endothelial Markers May Link Kidney Function to Cardiovascular Events in Type 2 Diabetes
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Includes: Supplementary data
Journal Articles

Differential Effects of Two Isoenergetic Meals Rich in Saturated or Monounsaturated Fat on Endothelial Function in Subjects With Type 2 Diabetes

Nicholas Tentolouris, MD, Christina Arapostathi, MD, Despoina Perrea, PHD, Despoina Kyriaki, MD, Constantinos Revenas, MD, Nicholas Katsilambros, MD
Journal: Diabetes Care
Diabetes Care 2008;31(12):2276–2278
https://doi.org/10.2337/dc08-0924
Published: 01 December 2008
View article titled, Differential Effects of Two Isoenergetic Meals Rich in Saturated or Monounsaturated Fat on Endothelial Function in Subjects With Type 2 Diabetes
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Journal Articles

Effect of Insulin Glulisine on Microvascular Blood Flow and Endothelial Function in the Postprandial State

Clothilde Hohberg, MD, Thomas Forst, MD, Martin Larbig, PHD, Michael Safinowski, PHD, Stefan Diessel, MD, Silvia Hehenwarter, Matthias M. Weber, MD, Thomas Schöndorf, PHD, Andreas Pfützner, MD, PHD
Journal: Diabetes Care
Diabetes Care 2008;31(5):1021–1025
https://doi.org/10.2337/dc07-2185
Published: 01 May 2008
View article titled, Effect of Insulin Glulisine on Microvascular Blood Flow and Endothelial Function in the Postprandial State
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Journal Articles

Long-Term N-Acetylcysteine and l-Arginine Administration Reduces Endothelial Activation and Systolic Blood Pressure in Hypertensive Patients With Type 2 Diabetes

Valentino Martina, MD, Andi Masha, MD, Valentina Ramella Gigliardi, MD, Loredana Brocato, MD, Enzo Manzato, MD, PHD, Arrigo Berchio, MD, Paola Massarenti, MD, Fabio Settanni, PHD, Lara Della Casa, PHD, Stefania Bergamini, PHD, Anna Iannone, MD, PHD
Journal: Diabetes Care
Diabetes Care 2008;31(5):940–944
https://doi.org/10.2337/dc07-2251
Published: 01 May 2008
View article titled, Long-Term <em>N</em>-Acetylcysteine and <sc>l</sc>-Arginine Administration Reduces Endothelial Activation and Systolic Blood Pressure in Hypertensive Patients With Type 2 Diabetes
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Journal Articles

Overweight Latino Children and Adolescents Have Marked Endothelial Dysfunction and Subclinical Vascular Inflammation in Association With Excess Body Fat and Insulin Resistance

A. Enrique Caballero, MD, Kelb Bousquet-Santos, DSC, Ludivina Robles-Osorio, MD, Valeria Montagnani, RN, Geetha Soodini, MD, Sriurai Porramatikul, MD, Osama Hamdy, MD, Antonio C.L. Nobrega, MD, DSC, Edward S. Horton, MD
Journal: Diabetes Care
Diabetes Care 2008;31(3):576–582
https://doi.org/10.2337/dc07-1540
Published: 01 March 2008
View article titled, Overweight Latino Children and Adolescents Have Marked Endothelial Dysfunction and Subclinical Vascular Inflammation in Association With Excess Body Fat and Insulin Resistance
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Journal Articles

Cardiovascular Complications in Diabetes: Targets and interventions

Alin O. Stirban, MD, Diethelm Tschoepe, MD
Journal: Diabetes Care
Diabetes Care 2008;31(Supplement_2):S215–S221
https://doi.org/10.2337/dc08-s257
Published: 01 February 2008
View article titled, Cardiovascular Complications in Diabetes: <subtitle>Targets and interventions</subtitle>
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