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Journal Articles

Safety and Efficacy of the Omnipod 5 Automated Insulin Delivery System in Adults With Type 2 Diabetes: From Injections to Hybrid Closed-Loop Therapy

Georgia M. Davis, Anne L. Peters, Bruce W. Bode, Anders L. Carlson, Bonnie Dumais, Todd E. Vienneau, Lauren M. Huyett, Trang T. Ly
Journal: Diabetes Care
Diabetes Care 2023;46(4):742–750
https://doi.org/10.2337/dc22-1915
Published: 14 February 2023
View article titled, Safety and Efficacy of the Omnipod 5 Automated Insulin Delivery System in Adults With Type 2 Diabetes: From Injections to Hybrid Closed-Loop Therapy
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Journal Articles

Safety and Glycemic Outcomes With a Tubeless Automated Insulin Delivery System in Very Young Children With Type 1 Diabetes: A Single-Arm Multicenter Clinical Trial

Jennifer L. Sherr, Bruce W. Bode, Gregory P. Forlenza, Lori M. Laffel, Melissa J. Schoelwer, Bruce A. Buckingham, Amy B. Criego, Daniel J. DeSalvo, Sarah A. MacLeish, David W. Hansen, Trang T. Ly
Journal: Diabetes Care
Diabetes Care 2022;45(8):1907–1910
https://doi.org/10.2337/dc21-2359
Published: 26 July 2022
View article titled, Safety and Glycemic Outcomes With a Tubeless Automated Insulin Delivery System in Very Young Children With Type 1 Diabetes: A Single-Arm Multicenter Clinical Trial
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Journal Articles

Multicenter Trial of a Tubeless, On-Body Automated Insulin Delivery System With Customizable Glycemic Targets in Pediatric and Adult Participants With Type 1 Diabetes

Sue A. Brown, Gregory P. Forlenza, Bruce W. Bode, Jordan E. Pinsker, Carol J. Levy, Amy B. Criego, David W. Hansen, Irl B. Hirsch, Anders L. Carlson, Richard M. Bergenstal, Jennifer L. Sherr, Sanjeev N. Mehta, Lori M. Laffel, Viral N. Shah, Anuj Bhargava, Ruth S. Weinstock, Sarah A. MacLeish, Daniel J. DeSalvo, Thomas C. Jones, Grazia Aleppo, Bruce A. Buckingham, Trang T. Ly, Omnipod 5 Research Group, Sue A. Brown, Mary Voelmle, Emma Emory, Gregory P. Forlenza, R. Paul Wadwa, Robert Slover, Erin Cobry, Laurel H. Messer, Cari Berget, Susan McCoy, Viral N. Shah, Halis K. Akturk, Nicole Schneider, Hal Joseph, Prakriti Joshee, Christie Beatson, Bruce W. Bode, Brooke Narron, Tricia Lopez, Jordan E. Pinsker, Mei Mei Church, Kristin Castorino, Molly Piper, Jimena Perez, Carol J. Levy, David W. Lam, Camilla Levister, Grenye O’Malley, Selassie Ogyaadu, Dushyanthy Arasaratnam, Mitchell Plesser, Emily Nosova, Suzan Bzdick, David W. Hansen, Sheri L. Stone, Ruth S. Weinstock, Irl B. Hirsch, Subbulaxmi Trikudanathan, Nancy Sanborn, Dori Khakpour, Anders L. Carlson, Amy B. Criego, Richard M. Bergenstal, Thomas Martens, Aimee Grieme, Jamie Hyatt, Alina Punel, Diane Whipple, Jennifer L. Sherr, Michelle Van Name, Michelle Brei, Melinda Zgorski, Amy Steffen, Lori Carria, Sanjeev N. Mehta, Lori M. Laffel, Lindsay Roethke, Margaret Fisher, Rebecca Ortiz La Banca, Lisa Volkening, Louise Ambler-Osborn, Christine Turcotte, Emily F. Freiner, Anuj Bhargava, Lisa Borg, Sarah A. MacLeish, Jamie R. Wood, Beth A. Kaminski, Terri L. Casey, Wendy Campbell, Daniel J. DeSalvo, Siripoom McKay, Mary Kylie DeLaO, Carolina Villegas, Thomas C. Jones, Barry Russel Johns, Ashwini Gore, Leslie Harvill, Kayla Merritt, Jennifer Stanfield, Jennifer Sheldon, Lisa Hichkad, Erica Burnett, Alicia Castelot, Lindsay Bounds, Kaitlyn Preston, Rebecca Goldfaden, Grazia Aleppo, Jelena Kravarusic, Anupam Bansal, Bruce A. Buckingham, Laya Ekhlaspour, Ryan Kingman, Kaisa Kivilaid, Krista Kleve, Trang T. Ly, Bonnie Dumais, Todd Vienneau, Lauren M. Huyett, Joon Bok Lee, Jason O’Connor, Eric Benjamin
Journal: Diabetes Care
Diabetes Care 2021;44(7):1630–1640
https://doi.org/10.2337/dc21-0172
Published: 20 July 2021
View article titled, Multicenter Trial of a Tubeless, On-Body Automated Insulin Delivery System With Customizable Glycemic Targets in Pediatric and Adult Participants With Type 1 Diabetes
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Journal Articles

The SimpliciT1 Study: A Randomized, Double-Blind, Placebo-Controlled Phase 1b/2 Adaptive Study of TTP399, a Hepatoselective Glucokinase Activator, for Adjunctive Treatment of Type 1 Diabetes

Klara R. Klein, Jennifer L.R. Freeman, Imogene Dunn, Chris Dvergsten, M. Sue Kirkman, John B. Buse, Carmen Valcarce, SimpliciT1 research group, John B. Buse, Klara R. Klein, M. Sue Kirkman, Katherine A. Bergamo, Elizabeth H. Harris, Jean M. Dostou, Laura A. Young, Sriram Machineni, Alex M. Kass, Jamie C. Diner, Milana Dezube, Virginia C. Purrington, Julie M. Uehling, Rachael M. Fraser, Katherine R. Schuch, Jennifer V. Rowell, Ali Qamar, K. Jean Lucas, Luke Snedaker, Stephanie Hoover, Justin Smith, Paul Becton, Jeffrey Hainsworth, Timothy S. Bailey, Juan Pablo Garcia-Naranjo, Niki Nguyen, Bruce W. Bode, Jennifer M. Boyd, Betsy Childs, Pablo Mora, Allison Camacho, Carl D. Vance, Karen Lugo, Anuj Bhargava, Kirstie Stifel, Lisa B. Connery, Birjis Khan, Simone D. Smith, John Parker, Kathryn Zweier, Emily Kronenfeld, Brittany Savoca, Viral N. Shah, Prakriti Joshee, Shivani Dixit, Hal Joseph, Halis Kaan Akturk, Subbulaxami Trikudanathan, Dori Khakpour, Julia Chang, Anne Peters, Pejman Cohan, Mark Harmel, Wendy S . Lane
Journal: Diabetes Care
Diabetes Care 2021;44(4):960–968
https://doi.org/10.2337/dc20-2684
Published: 23 February 2021
View article titled, The SimpliciT1 Study: A Randomized, Double-Blind, Placebo-Controlled Phase 1b/2 Adaptive Study of TTP399, a Hepatoselective Glucokinase Activator, for Adjunctive Treatment of Type 1 Diabetes
Open the PDF for The SimpliciT1 Study: A Randomized, Double-Blind, Placebo-Controlled Phase 1b/2 Adaptive Study of TTP399, a Hepatoselective Glucokinase Activator, for Adjunctive Treatment of Type 1 Diabetes in another window
Journal Articles

Efficacy and Safety of Fast-Acting Insulin Aspart Compared With Insulin Aspart, Both in Combination With Insulin Degludec, in Children and Adolescents With Type 1 Diabetes: The onset 7 Trial

Bruce W. Bode, Violeta Iotova, Margarita Kovarenko, Lori M. Laffel, Paturi V. Rao, Srikanth Deenadayalan, Magnus Ekelund, Steffen Falgreen Larsen, Thomas Danne
Journal: Diabetes Care
Diabetes Care 2019;42(7):1255–1262
https://doi.org/10.2337/dc19-0009
Published: 10 May 2019
View article titled, Efficacy and Safety of Fast-Acting Insulin Aspart Compared With Insulin Aspart, Both in Combination With Insulin Degludec, in Children and Adolescents With Type 1 Diabetes: The onset 7 Trial
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Includes: Supplementary data
Journal Articles

International Consensus on Risk Management of Diabetic Ketoacidosis in Patients With Type 1 Diabetes Treated With Sodium–Glucose Cotransporter (SGLT) Inhibitors

Thomas Danne, Satish Garg, Anne L. Peters, John B. Buse, Chantal Mathieu, Jeremy H. Pettus, Charles M. Alexander, Tadej Battelino, F. Javier Ampudia-Blasco, Bruce W. Bode, Bertrand Cariou, Kelly L. Close, Paresh Dandona, Sanjoy Dutta, Ele Ferrannini, Spiros Fourlanos, George Grunberger, Simon R. Heller, Robert R. Henry, Martin J. Kurian, Jake A. Kushner, Tal Oron, Christopher G. Parkin, Thomas R. Pieber, Helena W. Rodbard, Desmond Schatz, Jay S. Skyler, William V. Tamborlane, Koutaro Yokote, Moshe Phillip
Journal: Diabetes Care
Diabetes Care 2019;42(6):1147–1154
https://doi.org/10.2337/dc18-2316
Published: 06 February 2019
View article titled, International Consensus on Risk Management of Diabetic Ketoacidosis in Patients With Type 1 Diabetes Treated With Sodium–Glucose Cotransporter (SGLT) Inhibitors
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Includes: Supplementary data
Journal Articles

Sotagliflozin in Combination With Optimized Insulin Therapy in Adults With Type 1 Diabetes: The North American inTandem1 Study

John B. Buse, Satish K. Garg, Julio Rosenstock, Timothy S. Bailey, Phillip Banks, Bruce W. Bode, Thomas Danne, Jake A. Kushner, Wendy S. Lane, Pablo Lapuerta, Darren K. McGuire, Anne L. Peters, John Reed, Sangeeta Sawhney, Paul Strumph
Journal: Diabetes Care
Diabetes Care 2018;41(9):1970–1980
https://doi.org/10.2337/dc18-0343
Published: 24 June 2018
View article titled, Sotagliflozin in Combination With Optimized Insulin Therapy in Adults With Type 1 Diabetes: The North American inTandem1 Study
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Includes: Supplementary data
Journal Articles

Response to Comment on Russell-Jones et al. Diabetes Care 2017;40:943–950. Comment on Bowering et al. Diabetes Care 2017;40:951–957

Bruce W. Bode, Keith Bowering, David Russell-Jones
Journal: Diabetes Care
Diabetes Care 2018;41(3):e29–e30
https://doi.org/10.2337/dci17-0051
Published: 12 February 2018
View article titled, Response to Comment on Russell-Jones et al. Diabetes Care 2017;40:943–950. Comment on Bowering et al. Diabetes Care 2017;40:951–957
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Journal Articles

Faster Aspart Versus Insulin Aspart as Part of a Basal-Bolus Regimen in Inadequately Controlled Type 2 Diabetes: The onset 2 Trial

Keith Bowering, Christopher Case, John Harvey, Michael Reeves, Michael Sampson, Robert Strzinek, Ditte-Marie Bretler, Rikke Beck Bang, Bruce W. Bode
Journal: Diabetes Care
Diabetes Care 2017;40(7):951–957
https://doi.org/10.2337/dc16-1770
Published: 08 May 2017
View article titled, Faster Aspart Versus Insulin Aspart as Part of a Basal-Bolus Regimen in Inadequately Controlled Type 2 Diabetes: The onset 2 Trial
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Includes: Supplementary data
Journal Articles

Fast-Acting Insulin Aspart Improves Glycemic Control in Basal-Bolus Treatment for Type 1 Diabetes: Results of a 26-Week Multicenter, Active-Controlled, Treat-to-Target, Randomized, Parallel-Group Trial (onset 1)

David Russell-Jones, Bruce W. Bode, Christophe De Block, Edward Franek, Simon R. Heller, Chantal Mathieu, Athena Philis-Tsimikas, Ludger Rose, Vincent C. Woo, Anne Birk Østerskov, Tina Graungaard, Richard M. Bergenstal
Journal: Diabetes Care
Diabetes Care 2017;40(7):943–950
https://doi.org/10.2337/dc16-1771
Published: 29 March 2017
View article titled, Fast-Acting Insulin Aspart Improves Glycemic Control in Basal-Bolus Treatment for Type 1 Diabetes: Results of a 26-Week Multicenter, Active-Controlled, Treat-to-Target, Randomized, Parallel-Group Trial (onset 1)
Open the PDF for Fast-Acting Insulin Aspart Improves Glycemic Control in Basal-Bolus Treatment for Type 1 Diabetes: Results of a 26-Week Multicenter, Active-Controlled, Treat-to-Target, Randomized, Parallel-Group Trial (onset 1) in another window
Includes: Supplementary data
Journal Articles

REPLACE-BG: A Randomized Trial Comparing Continuous Glucose Monitoring With and Without Routine Blood Glucose Monitoring in Adults With Well-Controlled Type 1 Diabetes

Grazia Aleppo, Katrina J. Ruedy, Tonya D. Riddlesworth, Davida F. Kruger, Anne L. Peters, Irl Hirsch, Richard M. Bergenstal, Elena Toschi, Andrew J. Ahmann, Viral N. Shah, Michael R. Rickels, Bruce W. Bode, Athena Philis-Tsimikas, Rodica Pop-Busui, Henry Rodriguez, Emily Eyth, Anuj Bhargava, Craig Kollman, Roy W. Beck, for the REPLACE-BG Study Group
Journal: Diabetes Care
Diabetes Care 2017;40(4):538–545
https://doi.org/10.2337/dc16-2482
Published: 16 February 2017
View article titled, REPLACE-BG: A Randomized Trial Comparing Continuous Glucose Monitoring With and Without Routine Blood Glucose Monitoring in Adults With Well-Controlled Type 1 Diabetes
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Includes: Supplementary data
Journal Articles

Inhaled Technosphere Insulin Compared With Injected Prandial Insulin in Type 1 Diabetes: A Randomized 24-Week Trial

Bruce W. Bode, Janet B. McGill, Daniel L. Lorber, Jorge L. Gross, P.-C. Chang, David B. Bregman, for the Affinity 1 Study Group
Journal: Diabetes Care
Diabetes Care 2015;38(12):2266–2273
https://doi.org/10.2337/dc15-0075
Published: 15 July 2015
View article titled, Inhaled Technosphere Insulin Compared With Injected Prandial Insulin in Type 1 Diabetes: A Randomized 24-Week Trial
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Includes: Supplementary data
Journal Articles

Sotagliflozin, a Dual SGLT1 and SGLT2 Inhibitor, as Adjunct Therapy to Insulin in Type 1 Diabetes

Arthur T. Sands, Brian P. Zambrowicz, Julio Rosenstock, Pablo Lapuerta, Bruce W. Bode, Satish K. Garg, John B. Buse, Phillip Banks, Rubina Heptulla, Marc Rendell, William T. Cefalu, Paul Strumph
Journal: Diabetes Care
Diabetes Care 2015;38(7):1181–1188
https://doi.org/10.2337/dc14-2806
Published: 11 June 2015
View article titled, Sotagliflozin, a Dual SGLT1 and SGLT2 Inhibitor, as Adjunct Therapy to Insulin in Type 1 Diabetes
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Includes: Supplementary data
Journal Articles

Response to Comment on Wong et al. Real-Time Continuous Glucose Monitoring Among Participants in the T1D Exchange Clinic Registry. Diabetes Care 2014;37:2702–2709

Jenise C. Wong, Nicole C. Foster, David M. Maahs, Dan Raghinaru, Richard M. Bergenstal, Andrew J. Ahmann, Anne L. Peters, Bruce W. Bode, Grazia Aleppo, Irl B. Hirsch, Lora Kleis, H. Peter Chase, Stephanie N. DuBose, Kellee M. Miller, Roy W. Beck, Saleh Adi
Journal: Diabetes Care
Diabetes Care 2015;38(4):e61
https://doi.org/10.2337/dc14-2782
Published: 14 March 2015
View article titled, Response to Comment on Wong et al. Real-Time Continuous Glucose Monitoring Among Participants in the T1D Exchange Clinic Registry. Diabetes Care 2014;37:2702–2709
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Journal Articles

Low-Dose Otelixizumab Anti-CD3 Monoclonal Antibody DEFEND-1 Study: Results of the Randomized Phase III Study in Recent-Onset Human Type 1 Diabetes

Ronnie Aronson, Peter A. Gottlieb, Jens S. Christiansen, Thomas W. Donner, Emanuele Bosi, Bruce W. Bode, Paolo Pozzilli, the DEFEND Investigator Group
Journal: Diabetes Care
Diabetes Care 2014;37(10):2746–2754
https://doi.org/10.2337/dc13-0327
Published: 10 September 2014
View article titled, Low-Dose Otelixizumab Anti-CD3 Monoclonal Antibody DEFEND-1 Study: Results of the Randomized Phase III Study in Recent-Onset Human Type 1 Diabetes
Open the PDF for Low-Dose Otelixizumab Anti-CD3 Monoclonal Antibody DEFEND-1 Study: Results of the Randomized Phase III Study in Recent-Onset Human Type 1 Diabetes in another window
Includes: Supplementary data
Journal Articles

Real-Time Continuous Glucose Monitoring Among Participants in the T1D Exchange Clinic Registry

Jenise C. Wong, Nicole C. Foster, David M. Maahs, Dan Raghinaru, Richard M. Bergenstal, Andrew J. Ahmann, Anne L. Peters, Bruce W. Bode, Grazia Aleppo, Irl B. Hirsch, Lora Kleis, H. Peter Chase, Stephanie N. DuBose, Kellee M. Miller, Roy W. Beck, Saleh Adi, for the T1D Exchange Clinic Network
Journal: Diabetes Care
Diabetes Care 2014;37(10):2702–2709
https://doi.org/10.2337/dc14-0303
Published: 10 September 2014
View article titled, Real-Time Continuous Glucose Monitoring Among Participants in the T1D Exchange Clinic Registry
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Includes: Supplementary data
Journal Articles

Glucommander: A computer-directed intravenous insulin system shown to be safe, simple, and effective in 120,618 h of operation

Paul C. Davidson, MD, R. Dennis Steed, MD, Bruce W. Bode, MD
Journal: Diabetes Care
Diabetes Care 2005;28(10):2418–2423
https://doi.org/10.2337/diacare.28.10.2418
Published: 01 October 2005
View article titled, Glucommander: <subtitle>A computer-directed intravenous insulin system shown to be safe, simple, and effective in 120,618 h of operation</subtitle>
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Journal Articles

Glycemic Characteristics in Continuously Monitored Patients With Type 1 and Type 2 Diabetes: Normative values

Bruce W. Bode, MD, Sherwyn Schwartz, MD, Harrison A. Stubbs, PHD, Jon E. Block, PHD
Journal: Diabetes Care
Diabetes Care 2005;28(10):2361–2366
https://doi.org/10.2337/diacare.28.10.2361
Published: 01 October 2005
View article titled, Glycemic Characteristics in Continuously Monitored Patients With Type 1 and Type 2 Diabetes: <subtitle>Normative values</subtitle>
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Journal Articles

Efficacy of Inhaled Insulin in Patients With Type 2 Diabetes not Controlled With Diet and Exercise: A 12-week, randomized, comparative trial

Ralph A. DeFronzo, MD, Richard M. Bergenstal, MD, William T. Cefalu, MD, John Pullman, MD, Sam Lerman, MD, Bruce W. Bode, MD, Lawrence S. Phillips, MD, for the Exubera Phase III Study Group
Journal: Diabetes Care
Diabetes Care 2005;28(8):1922–1928
https://doi.org/10.2337/diacare.28.8.1922
Published: 01 August 2005
View article titled, Efficacy of Inhaled Insulin in Patients With Type 2 Diabetes not Controlled With Diet and Exercise: <subtitle>A 12-week, randomized, comparative trial</subtitle>
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Journal Articles

Continuous Subcutaneous Insulin Infusion (CSII) of Insulin Aspart Versus Multiple Daily Injection of Insulin Aspart/Insulin Glargine in Type 1 Diabetic Patients Previously Treated With CSII

Irl B. Hirsch, MD, Bruce W. Bode, MD, Satish Garg, MD, Wendy S. Lane, MD, Allen Sussman, MD, Peter Hu, PhD, Olga M. Santiago, MD, Jerzy W. Kolaczynski, MD, for the Insulin Aspart CSII/MDI Comparison Study Group
Journal: Diabetes Care
Diabetes Care 2005;28(3):533–538
https://doi.org/10.2337/diacare.28.3.533
Published: 01 March 2005
View article titled, Continuous Subcutaneous Insulin Infusion (CSII) of Insulin Aspart Versus Multiple Daily Injection of Insulin Aspart/Insulin Glargine in Type 1 Diabetic Patients Previously Treated With CSII
Open the PDF for Continuous Subcutaneous Insulin Infusion (CSII) of Insulin Aspart Versus Multiple Daily Injection of Insulin Aspart/Insulin Glargine in Type 1 Diabetic Patients Previously Treated With CSII in another window