Diabetes Care "On Air" Podcast
Diabetes Care "On Air" is the monthly podcast of the American Diabetes Association’s premier clinical research journal Diabetes Care. In each episode, co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, interview key authors of editor-selected feature articles and highlight the latest research presented in Diabetes Care. The podcast is intended for diabetes researchers and specialists, endocrinologists, and other health care professionals. Join Alice and Mike as they explore the latest high-impact research and information on diabetes care, treatment, and prevention. Learn more about the journal at Diabetes Care.
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October 26, 2023
Episode Notes and Sources
Episode Notes
Welcome to episode no. 12 (November 2023) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the November 2023 issue of Diabetes Care.
1:43: Mike gets things started with a November fun fact about diabetes: World Diabetes Day is November 14th! The 14th of November was chosen because it is Sir Fredrick Banting’s birthday. More information on World Diabetes Day can be found at worlddiabetesday.org.
2:20: Mike interviews Naveed Sattar, lead author of “Prediction of Cardiometabolic Health Through Changes in Plasma Proteins With Intentional Weight Loss in the DiRECT and DIADEM-I Randomized Clinical Trials of Type 2 Diabetes Remission.” This study is an editor-selected feature article appearing in the November 2023 issue and is openly accessible at https://doi.org/10.2337/dc23-0602
18:37: Alice interviews Alexander Kutz, lead author of “Comparative Cardiovascular Effectiveness and Safety of SGLT-2 Inhibitors, GLP-1 Receptor Agonists, and DPP-4 Inhibitors According to Frailty in Type 2 Diabetes.” This study is also an editor-selected feature article appearing in the November 2023 issue and is openly accessible at https://doi.org/10.2337/dc23-0671.
30:15: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the November 2023 issue of Diabetes Care. Studies highlighted in this segment include:
Episode Sources
Declining Incidence Rates of Distal Symmetric Polyneuropathy in People With Type 1 and Type 2 Diabetes in Denmark, With Indications of Distinct Patterns in Type 1 Diabetes. H. Mizrak et al. Diabetes Care 2023;46(11):1997–2003. https://doi.org/10.2337/dc23-0312.
Effect of Conventional Lifestyle Interventions on Type 2 Diabetes Incidence by Glucose-Defined Prediabetes Phenotype: An Individual Participant Data Meta-analysis of Randomized Controlled Trials. T. Sathish et al. Diabetes Care 2023;46(11):1903–1907. https://doi.org/10.2337/dc23-0696.
Time Trends in the Incidence of Diabetic Ketoacidosis Leading to Hospital Admission Among Adults With Type 1 Diabetes: A Nationwide Danish Register Study. E. Stougaard et al. Diabetes Care 2023;46(11):1897–1902. https://doi.org/10.2337/dc23-0475.
Point-of-Care Capillary Blood Ketone Measurements and the Prediction of Future Ketoacidosis Risk in Type 1 Diabetes. C. Song et al. Diabetes Care 2023;46(11):1973–1977. https://doi.org/10.2337/dc23-0840.
Randomization to a Provided Higher-Complex-Carbohydrate Versus Conventional Diet in Gestational Diabetes Mellitus Results in Similar Newborn Adiposity. T. Hernandez et al. Diabetes Care 2023;46(11):1931–1940. https://doi.org/10.2337/dc23-0617.
Fully Closed-Loop Glucose Control Compared With Insulin Pump Therapy With Continuous Glucose Monitoring in Adults With Type 1 Diabetes and Suboptimal Glycemic Control: A Single-Center, Randomized, Crossover Study. C. Boughton et al. Diabetes Care 2023;46(11):1916–1922. https://doi.org/10.2337/dc23-0728.
The Relationship Between Alcohol Consumption, BMI, and Type 2 Diabetes: A Systematic Review and Dose-Response Meta-analysis. L. Llamosas-Falcón et al. Diabetes Care 2023;46(11):2076–2083. https://doi.org/10.2337/dc23-1015.
September 29, 2023
Episode Notes and Sources
Episode Notes
Remembering a critical breakthrough in diabetes research on a fateful night over 100 years ago, Anand E. Rajesh and Aaron Y. Lee on the incredible potential of artificial intelligence in screening for and diagnosing diabetic retinopathy, Brigitte I. Frohnert on stage 1 type 1 diabetes and multiple islet autoimmunity, and more!
Welcome to episode no. 11 (October 2023) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the October 2023 issue of Diabetes Care.
0:45: Alice kicks off the episode with a fun October fact about a critical breakthrough in diabetes research that occurred in 1920. This breakthrough came in the form of an idea in a dream of Sir Fredrick Banting in the early morning hours of Halloween that year, and this idea contributed greatly to the discovery and successful purification of insulin.
2:20: Alice interviews Anand E. Rajesh and Aaron Y. Lee, authors of “Artificial Intelligence and Diabetic Retinopathy: AI Framework, Prospective Studies, Head-to-head Validation, and Cost-effectiveness” This study is an editor-selected feature article appearing in the October 2023 issue and is openly accessible at https://doi.org/10.2337/dci23-0032.
22:54: Mike interviews Brigitte I. Frohnert, lead author of “Refining the Definition of Stage 1 Type 1 Diabetes: An Ontology-Driven Analysis of the Heterogeneity of Multiple Islet Autoimmunity.” This study is also an editor-selected feature article appearing in the October 2023 issue and is openly accessible at https://doi.org/10.2337/dc22-1960.
43:36: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the October 2023 issue of Diabetes Care. Studies highlighted in this segment include:
Episode Sources
Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus. D. Sacks et al. Diabetes Care 2023;46(10):e151–e199. https://doi.org/10.2337/dci23-0036.
Effect of Postmenopausal Hormone Therapy on Glucose Regulation in Women With Type 1 or Type 2 Diabetes: A Systematic Review and Meta-analysis. E. Speksnijder et al. Diabetes Care 2023;46(10):1866–1875. https://doi.org/10.2337/dc23-0451.
Genetic Evidence Strongly Supports Managing Weight and Blood Pressure in Addition to Glycemic Control in Preventing Vascular Complications in People With Type 2 Diabetes. A. Ahmed et al. Diabetes Care 2023;46(10):1783–1791. https://doi.org/10.2337/dc23-0855.
All-Cause Mortality and Cardiovascular and Microvascular Diseases in Latent Autoimmune Diabetes in Adults. Y. Wei et al. Diabetes Care 2023;46(10):1857–1865. https://doi.org/10.2337/dc23-0739.
Type 1 Diabetes Genetic Risk Score Differentiates Subgroups of Ketosis-Prone Diabetes. D. Osafehinti et al. Diabetes Care 2023;46(10):1778–1782. https://doi.org/10.2337/dc23-0622.
A Skin Care Program to Prevent Skin Problems due to Diabetes Devices in Children and Adolescents: A Cluster-Controlled Intervention Study. A. Berg et al. Diabetes Care 2023;46(10):1770–1777. https://doi.org/10.2337/dc23-0462.
September 5, 2023
Episode Notes and Sources
Episode Notes
Announcement of an upcoming special episode of Diabetes Care “On Air” on diabetes and social determinants of health, Sandra C. Naamann and George L. Bakris on the pillars of therapy for slowing diabetes progression, Mathilde Touvier on artificial sweeteners and type 2 diabetes risk, and more!
Welcome to episode no. 10 (September 2023) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the September 2023 issue of Diabetes Care.
0:43: Alice announces a special episode of Diabetes Care “On Air,” to be released later in the month. This special episode will focus on this year’s Diabetes Care Symposium on the impact of social determinants of health for diabetes development and care. The episode will feature a panel discussion with the authors of the articles presented at the symposium.
1:15: Mike interviews Sandra C. Naaman and George L. Bakris, authors of “Diabetic Nephropathy: Update on Pillars of Therapy Slowing Progression.” This study is an editor-selected feature article appearing in the September 2023 issue and is openly accessible at https://doi.org/10.2337/dci23-0030.
30:30: Alice interviews Mathilde Touvier, senior author of “Artificial Sweeteners and Risk of Type 2 Diabetes in the Prospective NutriNet-Santé Cohort.” This study is also an editor-selected feature article appearing in the September 2023 issue and is openly accessible at https://doi.org/10.2337/dc23-0206.
41:30: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the September 2023 issue of Diabetes Care. Studies highlighted in this segment include:
Episode Sources
Rapid Reduction of HbA1c and Early Worsening of Diabetic Retinopathy: A Real-World Population-Based Study in Subjects With Type 2 Diabetes. R. Simó et al. Diabetes Care 2023;46(9):1633–1639. https://doi.org/10.2337/dc22-2521.
Assessment of Meal Anticipation for Improving Fully Automated Insulin Delivery in Adults With Type 1 Diabetes. J. Garcia-Tirado et al. Diabetes Care 2023;46(9):1652–1658. https://doi.org/10.2337/dc23-0119.
Grading Fractures on Foot and Ankle X-rays and MRI Scans in the Active Charcot Foot in Diabetes: How Strong Is the Agreement Between Modalities? O. Artz et al. Diabetes Care 2023;46(9):1668–1672. https://doi.org/10.2337/dc23-0220.
Diet-Related Lipidomic Signatures and Changed Type 2 Diabetes Risk in a Randomized Controlled Feeding Study With Mediterranean Diet and Traditional Chinese or Transitional Diets. Y. Luo et al. Diabetes Care 2023;46(9):1691–1699. https://doi.org/10.2337/dc23-0314.
A Randomized Controlled Trial Comparing the Efficacy and Safety of IDegLira Versus Basal-Bolus in Patients With Poorly Controlled Type 2 Diabetes and Very High HbA1c ≥9–15%: DUAL HIGH Trial. R.J. Galindo et al. Diabetes Care 2023;46(9):1640–1645. https://doi.org/10.2337/dc22-2426.
Evaluation of Insulin Pump Infusion Sites in Type 1 Diabetes: The DERMIS Study. A. Kalus et al. Diabetes Care 2023;46(9):1626–1632. https://doi.org/10.2337/dc23-0426.
August 2, 2023
Episode Notes and Sources
Episode Notes
Welcome to episode no. 9 (August 2023) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the August 2023 issue of Diabetes Care.
0:52: Before launching into this month’s feature interviews, Alice and Mike recap their first few months of working together on Diabetes Care “On Air.” Mike emphasizes how much he’s learned from the interviewees and from Alice, and he shares his hope that listeners also find the podcast enlightening. Alice has been impressed with how passionate the interviewers are about the diabetes research they are conducting. She also takes us behind the scenes to reveal that she performs her podcasting from her closet!
2:11: Mike interviews Elbert S. Huang, first author of “The Growing Role of Technology in the Care of Older Adults with Diabetes.” This study is an editor-selected feature article appearing in the August 2023 issue and is openly accessible at https://doi.org/10.2337/dci23-0021.
19:08: Alice interviews Lars J. Kjerpeseth, first author of “Metformin Versus Insulin and Risk of Major Congenital Malformations in Pregnancies With Type 2 Diabetes: A Nordic Register-Based Cohort Study.” This study is also an editor-selected feature article appearing in the August 2023 issue and is openly accessible at https://doi.org/10.2337/dc23-0256.
28:05: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the August 2023 issue of Diabetes Care. Studies highlighted in this segment include:
Episode Sources
Influence of Gestational Diabetes on Diabetes Risk and Glycemic Control in a Retrospective Population-Based Cohort. K.J. McCarthy et al. Diabetes Care 2023;46(8):1483–1491. https://doi.org/10.2337/dc22-1676.
The Association of Homelessness With Rates of Diabetes Complications: A Population-Based Cohort Study. R. Sharan et al. Diabetes Care 2023;46(8):1469–1476. https://doi.org/10.2337/dc23-0211.
Dulaglutide and Kidney Function-Related Outcomes in Type 2 Diabetes: A REWIND Post Hoc Analysis. F.T. Botros et al. Diabetes Care 2023;46(8):1524–1530. https://doi.org/10.2337/dc23-0231.
Effects of Tirzepatide Versus Insulin Glargine on Cystatin C-Based Kidney Function: A SURPASS-4 Post Hoc Analysis. H.J.L. Heerspink et al. Diabetes Care 2023;46(8):1501–1506. https://doi.org/10.2337/dc23-0261.
Diabetes Polygenic Score Predicts the Risk of Glucocorticoid-Induced Hyperglycemia in Patients Without Diabetes. A.J. Deutsch et al. Diabetes Care 2023;46(8):1541–1545. https://doi.org/10.2337/dc23-0353.
Effect of Early Glycemic Control in Youth-Onset Type 2 Diabetes on Longer-Term Glycemic Control and β-Cell Function: Results From the TODAY Study. K.J. Nadeau et al. Diabetes Care 2023;46(8):1507–1514. https://doi.org/10.2337/dc23-0560.
The Prevalence of Polyneuropathy in Type 2 Diabetes Subgroups Based on HOMA2 Indices of β-Cell Function and Insulin Sensitivity. F.P.B. Kristensen et al. Diabetes Care 2023;46(8):1546–1555. https://doi.org/10.2337/dc23-0079.
June 30, 2023
Episode Notes and Sources
Episode Notes
Welcome to episode no. 8 (July 2023) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the July 2023 issue of Diabetes Care.
0:42: Mike and Alice discuss the spectacularly successful 83rd Scientific Sessions of the ADA, which occurred June 23 to 26 in San Diego, CA. The co-hosts discuss the “incredible,” “exciting,” and “terrific” sessions, lectures, and study results presentations. Alice relates her joy in making new connections and renewing old ones, and Mike notes that the high in-person attendance infused the whole event with a dynamic, collaborative energy. He also highlights the timeliness and importance of the symposium on diabetes and social determinants of health (SDOH) that was featured at the Scientific Sessions. Alice and Mike plan to do a special podcast on the SDOH symposium in the near future.
4:02: Alice interviews Jean-Philippe Drouin-Chartier, senior author of the article “Ultra-Processed Food Consumption and Risk of Type 2 Diabetes: Three Large Prospective U.S. Cohort Studies.” This study is an editor-selected feature article appearing in the July 2023 issue and is openly accessible at https://doi.org/10.2337/dc22-1993.
15:20: Mike interviews Edward W. Gregg, lead author of “Use of Real-World Data in Population Science to Improve the Prevention and Care of Diabetes-Related Outcomes.” This study is also an editor-selected feature article appearing in the July 2023 issue and is openly accessible at https://doi.org/10.2337/dc22-1438.
27:50: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the July 2023 issue of Diabetes Care. Studies highlighted in this segment include:
Episode Sources
Potential Value of Identifying Type 2 Diabetes Subgroups for Guiding Intensive Treatment: A Comparison of Novel Data-Driven Clustering With Risk-Driven Subgroups. X. Li et al. Diabetes Care 2023;46(7):1395–1403. https://doi.org/10.2337/dc22-2170.
High Prevalence of NASH and Advanced Fibrosis in Type 2 Diabetes: A Prospective Study of 330 Outpatients Undergoing Liver Biopsies for Elevated ALT, Using a Low Threshold. L. Castera et al. Diabetes Care 2023;46(7):1354–1362. https://doi.org/10.2337/dc22-2048.
Association of Timing of Moderate-to-Vigorous Physical Activity With Changes in Glycemic Control Over 4 Years in Adults With Type 2 Diabetes From the Look AHEAD Trial. J. Qian et al. Diabetes Care 2023;46(7):1417–1424. https://doi.org/10.2337/dc22-2413.
Global Prevalence of Prediabetes. M.R. Rooney et al. Diabetes Care 2023;46(7):1388–1394. https://doi.org/10.2337/dc22-2376.
Metformin for Treatment of Acute COVID-19: Systematic Review of Clinical Trial Data Against SARS-CoV-2. S.M. Erickson et al. Diabetes Care 2023;46(7):1432–1442. https://doi.org/10.2337/dc22-2539.
At-Home Use of a Pregnancy-Specific Zone-MPC Closed-Loop System for Pregnancies Complicated by Type 1 Diabetes: A Single-Arm, Observational Multicenter Study. C.J. Levy et al. Diabetes Care 2023;46(7):1425–1431. https://doi.org/10.2337/dc23-0173.
June 2, 2023
Episode Notes and Sources
Episode Notes
Welcome to episode no. 7 (June 2023) of Diabetes Care "On Air"—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the June 2023 issue of Diabetes Care.
0:41: Mike and Alice discuss the 83rd Scientific Sessions of the ADA, which will occur June 23 to 26 in San Diego, CA. Alice, who happens to be the Chair of the Scientific Sessions Planning Committee, describes some of the exciting changes attendees can expect this year, and both co-hosts share which of the many lectures, debates, and sessions they are looking forward to the most, including a new event called The Innovation Challenge and the Keynote address by former director of the National Institutes of Health Dr. Francis Collins. Alice notes a debate in which our esteemed host Mike Rickels will be participating on b-cell replacement therapies vs. artificial pancreas technologies, and the results of several major clinical trials that will be presented, including SURMOUNT-2, OASIS 1, PIONEER PLUS, COORDINATE-Diabetes, and CLEAR Outcomes.
6:58: Mike interviews Angus G. Jones, senior author of the article “Age of Diagnosis Does Not Alter the Presentation or Progression of Robustly Defined Adult-Onset Type 1 Diabetes.” This study is an editor-selected feature article appearing in the June 2023 issue and is openly accessible at https://doi.org/10.2337/dc22-2159.
22:05: Alice has an enlightening chat with Andrea Kelly, one of the authors of the article “Cystic Fibrosis–Related Diabetes Workshop: Research Priorities Spanning Disease Pathophysiology, Diagnosis, and Outcomes.” This study is also an editor-selected feature article in the June 2023 issue and can be freely accessed at https://doi.org/10.2337/dc23-0380.
42:47: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the June 2023 issue of Diabetes Care. Studies highlighted in this segment include:
Episode Sources
Quantifying the Relationship Between Physical Activity Energy Expenditure and Incident Type 2 Diabetes: A Prospective Cohort Study of Device-Measured Activity in 90,096 Adults. T. Strain et al. Diabetes Care 2023;46(6):1145–1155. https://doi.org/10.2337/dc22-1467.
Higher Neighborhood Drivability Is Associated With a Higher Diabetes Risk in Younger Adults: A Population-Based Cohort Study in Toronto, Canada. N.R. den Braver et al. Diabetes Care 2023;46(6):1177–1184. https://doi.org/10.2337/dc22-1549.
Plasma Insulin Concentration in Newborns and Children and Age at Menarche. G. Wang et al. Diabetes Care 2023;46(6):1231–1238. https://doi.org/10.2337/dc22-2017.
Is the Biphasic Effect of Diabetes and Obesity on Fetal Growth a Risk Factor for Childhood Obesity? M.N.M. van Poppel et al. Diabetes Care 2023;46(6):1124–1131. https://doi.org/10.2337/dc22-2409.
Upper-Extremity Impairments in Type 1 Diabetes: Results From a Controlled Nationwide Study. S. Wagner et al. Diabetes Care 2023;46(6):1204–1208. https://doi.org/10.2337/dc23-0063.
The Insulin-Only Bionic Pancreas Improves Glycemic Control in Non-Hispanic White and Minority Adults and Children With Type 1 Diabetes. L.E. Castellanos et al. Diabetes Care 2023;46(6):1185–1190. https://doi.org/10.2337/dc22-1478.
A National Physician Survey of Deintensifying Diabetes Medications for Older Adults With Type 2 Diabetes. S.J. Pilla et al. Diabetes Care 2023;46(6):1164–1168. https://doi.org/10.2337/dc22-2146.
May 2, 2023
Episode Notes and Sources
Episode Notes
Welcome to episode no. 6 (May 2023) of Diabetes Care "On Air"—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the May 2023 issue of Diabetes Care.
1:45: Alice interviews Rohan Arora, contributor of the cover art on the May 2023 issue of Diabetes Care. Rohan was born in India and was diagnosed with diabetes 14 years ago. Today he is a designer, a researcher, and a certified diabetes educator. He is also the head of the Delhi Chapter of the Blue Circle Diabetes Foundation (bluecircle.foundation), a nongovernmental organization in India committed to diabetes education and advocacy. Rohan's artwork, "Sugar Moon," is inspired by "a mother's empathy and how with love and joy in small things we can overcome all odds." Please check out the cover and a brief profile of Rohan and his artwork in the May 2023 issue of Diabetes Care: https://diabetesjournals.org/care/issue/46/5.
7:42: Mike chats with William Russell of Vanderbilt University Medical Center. Dr. Russell is the lead author of "Abatacept for Delay of Type 1 Diabetes Progression in Stage 1 Relatives at Risk: A Randomized, Double-Masked, Controlled Trial," which was coordinated by the Type 1 Diabetes TrialNet Study Group. This study is an editor-selected feature article appearing in the May 2023 issue and is openly accessible at https://doi.org/10.2337/dc22-2200.
24:29: Alice discusses "Metformin and Cancer: Solutions to a Real-World Evidence Failure" with senior author Sammy Suissa of McGill University. As Alice describes, Dr. Suissa's review article, which is coauthored by Oriana Hoi Yun Yu, is "a cautionary tale of the potential pitfalls of observational study design and the steps we can take to right the wrongs of the past." This fascinating article can be freely accessed at https://doi.org/10.2337/dci22-0047.
41:31: In the "Diabetes Care Rapid Exchange," Alice and Mike wrap up the episode by reviewing several interesting articles in the May 2023 issue of Diabetes Care. Studies highlighted in this segment include:
Episode Sources
Distinct Mechanisms Responsible for the Increase in Glucose Production and Ketone Formation Caused by Empagliflozin in T2DM Patients. S. Abdelgani et al. Diabetes Care 2023;46(5):978–984. https://doi.org/10.2337/dc22-0885.
Relation of Incident Type 1 Diabetes to Recent COVID-19 Infection: Cohort Study Using e-Health Record Linkage in Scotland. P.M. McKeigue et al. Diabetes Care 2023;46(5):921–928. https://doi.org/10.2337/dc22-0385.
Comparative Incidence of Diabetes Following Hospital Admission for COVID-19 and Pneumonia: A Cohort Study. N. Holman et al. Diabetes Care 2023;46(5):938–943. https://doi.org/10.2337/dc22-0670.
Novel Once-Weekly Basal Insulin Fc Achieved Similar Glycemic Control With a Safety Profile Comparable to Insulin Degludec in Patients With Type 1 Diabetes. C.M. Kazda et al. Diabetes Care 2023;46(5):1052–1059. https://doi.org/10.2337/dc22-2395.
Once-Weekly Basal Insulin Fc Demonstrated Similar Glycemic Control to Once-Daily Insulin Degludec in Insulin-Naive Patients With Type 2 Diabetes: A Phase 2 Randomized Control Trial. J.M. Bue-Valleskey et al. Diabetes Care 2023;46(5):1060–1067. https://doi.org/10.2337/dc22-2396.
People With Type 1 Diabetes of African Caribbean Ethnicity Are at Increased Risk of Developing Sight-Threatening Diabetic Retinopathy. A. Mangelis et al. Diabetes Care 2023;46(5):1091–1097. https://doi.org/10.2337/dc22-2118.
Tirzepatide Reduces Appetite, Energy Intake, and Fat Mass in People With Type 2 Diabetes. T. Heise et al. Diabetes Care 2023;46(5):998–1004. https://doi.org/10.2337/dc22-1710.
Noninvasive Hypoglycemia Detection in People With Diabetes Using Smartwatch Data. V. Lehmann et al. Diabetes Care 2023;46(5):993–997. https://doi.org/10.2337/dc22-2290.
March 27, 2023
Episode Notes and Sources
Episode Notes
Welcome to episode no. 5 (April 2023) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the April 2023 issue of Diabetes Care.
0:52: Mike interviews Aaron J. Deutsch and Miriam S. Udler of the Harvard Medical School and Massachusetts General Hospital. Aaron and Miriam are the lead and senior authors, respectively, of “Polygenic Scores Help Reduce Racial Disparities in Predictive Accuracy of Automated Type 1 Diabetes Classification Algorithms.” This article, which can be freely accessed at https://doi.org/10.2337/dc22-1833, is one of the editor-selected feature articles in the April 2023 issue of Diabetes Care.
12:23: Alice is joined by Leonard E. Egede of the Medical College of Wisconsin. Dr. Egede is the lead author of “Structural Racism as an Upstream Social Determinant of Diabetes Outcomes: A Scoping Review,” another editor-selected article appearing in the April 2023 issue and openly accessible at https://doi.org/10.2337/dci22-0044.
21:05: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing several interesting articles in the April 2023 issue of Diabetes Care. Studies highlighted in this segment include:
Episode Sources
Examining the Acute Glycemic Effects of Different Types of Structured Exercise Sessions in Type 1 Diabetes in a Real-World Setting: The Type 1 Diabetes and Exercise Initiative (T1DEXI). M.C. Riddell et al. Diabetes Care 2023;46(4):704–713. https://doi.org/10.2337/dc22-1721.
Effect of Mini-Dose Ready-to-Use Liquid Glucagon on Preventing Exercise-Associated Hypoglycemia in Adults With Type 1 Diabetes. R. Aronson et al. Diabetes Care 2023;46(4):765–772. https://doi.org/10.2337/dc22-1145.
Proteomic Predictors of Incident Diabetes: Results From the Atherosclerosis Risk in Communities (ARIC) Study. M.R. Rooney et al. Diabetes Care 2023;46(4):733–741. https://doi.org/10.2337/dc22-1830.
Safety and Efficacy of the Omnipod 5 Automated Insulin Delivery System in Adults With Type 2 Diabetes: From Injections to Hybrid Closed-Loop Therapy. G.M. Davis et al. Diabetes Care 2023;46(4):742–750. https://doi.org/10.2337/dc22-1915.
Trends in the Prevalence of Lean Diabetes Among U.S. Adults, 2015–2020. T.P. Adesoba and C.C. Brown. Diabetes Care 2023;46(4):885–889. https://doi.org/10.2337/dc22-1847.
Retinopathy During the First 5 Years of Type 1 Diabetes and Subsequent Risk of Advanced Retinopathy. J.I. Malone et al. on behalf of the Diabetes Control and Complications Trial (DCCT)-Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group. Diabetes Care 2023;46(4):680–686. https://doi.org/10.2337/dc22-1711.
Exocrine Proteins Including Trypsin(ogen) as a Key Biomarker in Type 1 Diabetes. L. Bakinowska et al. Diabetes Care 2023;46(4):714–721. https://doi.org/10.2337/dc22-1317.
Growing Income-Related Disparities in Cardiovascular Hospitalizations Among People With Diabetes, 1995–2019: A Population-Based Study. B.R. Shah et al. Diabetes Care 2023;46(4):751–756. https://doi.org/10.2337/dc22-1936.
March 3, 2023
Episode Notes and Sources
Episode Notes
Welcome to episode no. 4 (March 2023) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life. Join co-hosts Alice Cheng, MD, FRCPC, and Michael Rickels, MD, MS, as they discuss the latest and greatest content in the March 2023 issue of Diabetes Care.
1:11: The March 2023 cover of Diabetes Care features a stunning self-portrait by Michael Natter, MD. Dr. Natter, who was diagnosed with type 1 diabetes at the age of 9, is an endocrinologist at NYU Langone Health. Before pursuing his medical degree, he studied visual art at Skidmore College. Dr. Natter shares with Alice how his background in studio art has allowed him to approach medicine through a nontraditional lens. Dr. Natter’s piece on the March 2023 cover is titled “Calloused Fingertips,” and as he explains, it is a self-portrait created through a mosaic of used diabetes test strips. Follow Dr. Natter on Instagram (@mike.natter), Twitter (@mike_natter), and TikTok (@mikenatter).
7:05: Mike interviews Wei Perng, PhD, MPH, of the University of Colorado School of Public Health, lead author of “Youth-Onset Type 2 Diabetes: The Epidemiology of an Awakening.” This Review article, which can be freely accessed at https://doi.org/10.2337/dci22-0046, is one of the editor-selected feature articles in the March 2023 issue of Diabetes Care.
26:40: Alice is joined by Louise L. Stentebjerg, MD, PhD-candidate, of Steno Diabetes Center Odense. Dr. Stentebjerg is the lead author of “Roux-en-Y Gastric Bypass Increases Glycemic Excursions During Pregnancy and Postpartum: A Prospective Cohort Study,” another editor-selected article appearing in the March 2023 issue and openly accessible at https://doi.org/10.2337/dc22-1357.
34:25: In the “Diabetes Care Rapid Exchange,” Alice and Mike wrap up the episode by reviewing other interesting articles in the March 2023 issue of Diabetes Care. Studies highlighted in this segment include:
Episode Sources
Two-Year Follow-up From the T1GER Study: Continued Off-Therapy Metabolic Improvements in Children and Young Adults With New-Onset T1D Treated With Golimumab and Characterization of Responders. M.R. Rigby et al. Diabetes Care 2023;46(3):561–569. https://doi.org/10.2337/dc22-0908.
Combination of Multiple Low-Risk Lifestyle Behaviors and Incident Type 2 Diabetes: A Systematic Review and Dose-Response Meta-analysis of Prospective Cohort Studies. T.A. Khan et al. Diabetes Care 2023;46(3):643–656. https://doi.org/10.2337/dc22-1024.
CGM Metrics Identify Dysglycemic States in Participants From the TrialNet Pathway to Prevention Study. D.M. Wilson et al. and the Type 1 Diabetes TrialNet Study Group. Diabetes Care 2023;46(3):526–534. https://doi.org/10.2337/dc22-1297.
Treatment of Gestational Diabetes Mellitus and Maternal Risk of Diabetes After Pregnancy. R. Retnakaran et al. Diabetes Care 2023;46(3):587–592. https://doi.org/10.2337/dc22-1786.
Optimization of Albuminuria-Lowering Treatment in Diabetes by Crossover Rotation to Four Different Drug Classes: A Randomized Crossover Trial. V. Rotbain Curovic et al. Diabetes Care 2023;46(3):593–601. https://doi.org/10.2337/dc22-1699.
Glucagon Prescribing and Costs Among U.S. Adults With Diabetes, 2011–2021. J.R. Herges et al. Diabetes Care 2023;46(3):620–627. https://doi.org/10.2337/dc22-1564.
February 20, 2023
Episode Notes and Sources
Episode Notes
Welcome to episode no. 3 (February 2023) of Diabetes Care “On Air”—a new and different way to bring the research published in Diabetes Care to life.
This special episode of Diabetes Care “On Air” is devoted to the National Clinical Care Commission (NCCC) Report to Congress.
The NCCC was a federal advisory committee charged with leveraging federal policies and programs to more effectively prevent and control diabetes. In January 2022, the NCCC issued its final report to Congress. That transformational report contained 39 specific recommendations, including 3 foundational recommendations, that addressed the necessity of an all-of-government approach to diabetes, health equity, and access to health care.
Diabetes Care is excited to announce that the February 2023 issue features an openly accessible seven-article collection that details the NCCC’s comprehensive recommendations to Congress.
And in this episode of Diabetes Care “On Air,” co-hosts Alice Cheng and Michael Rickels are joined by commission members Dr. Bill Herman, Dr. Dean Schillinger, and Dr. Paul Conlin to learn more about the foundational report and the NCCC’s specific recommendations. In addition, Dr. Neda Laiteerapong, a current associate editor of Diabetes Care, joined the team to discuss the key take-aways of the report for clinicians and health care teams.
We hope this special episode of Diabetes Care “On Air” inspires and motivates you to advocate for the critical recommendations outlined in the NCCC’s foundational report. Thank you for listening!
Episode Sources
The National Clinical Care Commission Report to Congress: Recommendations to Better Leverage Federal Policies and Programs to Prevent and Control Diabetes. W.H. Herman et al. Diabetes Care 2023;46(2):255–261. https://doi.org/10.2337/dc22-1587.
The National Clinical Care Commission Report to Congress: Background, Methods, and Foundational Recommendations. W.H. Herman et al. Diabetes Care 2023;46(2):e14–e23. https://doi.org/10.2337/dc22-0611.
The National Clinical Care Commission Report to Congress: Leveraging Federal Policies and Programs for Population-Level Diabetes Prevention and Control: Recommendations From the National Clinical Care Commission. D. Schillinger et al. Diabetes Care 2023;46(2):e24–e38. https://doi.org/10.2337/dc22-1611.
The National Clinical Care Commission Report to Congress: Leveraging Federal Policies and Programs to Prevent Diabetes in People With Prediabetes. J.M. Boltri et al. Diabetes Care 2023;46(2):e39–e50. https://doi.org/10.2337/dc22-0620.
The National Clinical Care Commission Report to Congress: Leveraging Federal Policies and Programs to Improve Diabetes Treatment and Reduce Complications.M. Carol Greenlee et al. Diabetes Care 2023;46(2):e51–e59. https://doi.org/10.2337/dc22-0621.
The National Clinical Care Commission Report to Congress: Summary and Next Steps. P.R. Conlin et al. Diabetes Care 2023;46(2):e60–e63. https://doi.org/10.2337/dc22-0622.
February 6, 2023
Episode Notes and Sources
Episode Notes
Welcome to episode no. 2 (February 2023) of Diabetes Care "On Air"—a new and different way to bring the research published in Diabetes Care to life. Co-hosts Alice Cheng, MD, and Michael Rickels, MD, MS, open by discussing a recently launched initiative to feature artwork created by people with diabetes and/or people affected by diabetes on each cover of Diabetes Care. The February 2023 cover features a powerful image by Jaserah Chowdury. More information about this initiative and Jaserah’s piece can be found in Editor-in-Chief Steven Kahn's editorial in the February issue.
Before launching into this episode’s interviews (see below), Alice and Mike note an important 5-article collection in the February issue on the National Clinical Care Commission Report to Congress on diabetes treatment and prevention. This openly accessible collection will be featured in the next episode of Diabetes Care "On Air", so make sure to check it out in advance. On to the interviews:
At 2:39, Mike interviews Michael W. Schwartz of the University of Washington and James S. Krinsley of Columbia University. Drs. Schwartz and Krinsley are the lead authors of "Brain Glucose Sensing and the Problem of Relative Hypoglycemia." This "Perspectives on Care" article, which can be freely accessed at https://doi.org/10.2337/dc22-1445, is one of the editor-selected feature articles in the February 2023 issue of Diabetes Care.
At 20:58, Alice is joined by Kamlesh Khunti of the University of Leicester. Dr. Khunti is the lead author of "The Impact of the COVID-19 Pandemic on Ethnic Minority Groups With Diabetes," another "Perspectives" article appearing in the February 2023 issue and openly accessible at https://doi.org/10.2337/dc21-2495. In the "Diabetes Care Rapid Exchange," at 33:58, Alice and Mike wrap up the episode by reviewing other interesting articles in the February 2023 issue of Diabetes Care. Studies highlighted in this segment are listed below.
Episode Sources
Vitamin D Status, Vitamin D Receptor Polymorphisms, and Risk of Microvascular Complications Among Individuals With Type 2 Diabetes: A Prospective Study. X. Chen et al. Diabetes Care 2023;46(2):270–277. https://doi.org/10.2337/dc22-0513.
Effectiveness of Nonmydriatic Ultra-Widefield Retinal Imaging to Screen for Diabetic Eye Disease: A Randomized Controlled Trial (Clearsight). S.L. Liu et al. Diabetes Care 2023;46(2):399–407. https://doi.org/10.2337/dc22-0713.
Urine Leucine-Rich α-2 Glycoprotein 1 (LRG1) Predicts the Risk of Progression to End-Stage Kidney Disease in Patients With Type 2 Diabetes. J.J. Liu et al. Diabetes Care 2023;46(2):408–415. https://doi.org/10.2337/dc22-1611.
Dietary Factors and All-Cause Mortality in Individuals With Type 2 Diabetes: A Systematic Review and Meta-analysis of Prospective Observational Studies. J. Barbaresko et al. Diabetes Care 2023;46(2):469–477. https://doi.org/10.2337/dc22-1018.
Prevalence and Predictors of Household Food Insecurity and Supplemental Nutrition Assistance Program Use in Youth and Young Adults With Diabetes: The SEARCH for Diabetes in Youth Study. F.S. Malik et al. Diabetes Care 2023;46(2):278–285. https://doi.org/10.2337/dc21-0790.
January 3, 2023
Episode Notes and Sources
Episode Notes
In this inaugural episode of Diabetes Care "On Air", Alice and Mike are first joined by the new editor of Diabetes Care, Dr. Steven Kahn (1:18). Steven shares his vision for the journal and discusses the new initiatives and features that the journal is launching in early 2023. (See Dr. Kahn’s editorial in the January 2023 issue.)
At 13:39, Alice interviews Nestoras Mathioudakis of Johns Hopkins University, the senior author of "Racial Disparities in Access and Use of Diabetes Technology Among Adult Patients With Type 1 Diabetes in a U.S. Academic Medical Center." This study, which is free to access, is an editor-selected feature article in the January 2023 issue of Diabetes Care.
At 26:45, Mike is joined by Patrik Smidtslund and Lena M. Thorn of the University of Helsinki. Patrik and Lena are the lead and senior authors, respectively, of "Prognosis After First-Ever Myocardial Infarction in Type 1 Diabetes Is Strongly Affected by Chronic Kidney Disease." This study is also free to access and is an editor-selected feature article in the January 2023 issue of Diabetes Care.
In the "Diabetes Care Rapid Exchange,” at 37:35, Alice and Mike wrap up the episode by discussing some of the other learnings in the January 2023 issue of Diabetes Care. Studies highlighted in this (and all) segments are listed under Sources below.
Episode Sources
Deficits and Disparities in Early Uptake of Glucagon-Like Peptide 1 Receptor Agonists and SGLT2i Among Medicare-Insured Adults Following a New Diagnosis of Cardiovascular Disease or Heart Failure. SJ Cromer et al. Diabetes Care 2023;46(1):65–74. https://doi.org/10.2337/dc22-0383.
Etiology, Epidemiology, and Disparities in the Burden of Diabetic Foot Ulcers (Review Article). K. McDermott et al. Diabetes Care 2023;46(1):209–221. https://doi.org/10.2337/dci22-0043.
Sustained Low Income, Income Changes, and Risk of All-Cause Mortality in Individuals With Type 2 Diabetes: A Nationwide Population-Based Cohort Study. H. Seok Lee et al. Diabetes Care 2023;46(1):92–100. https://doi.org/10.2337/dc21-2305.
Gestational Glucose Intolerance and Risk of Future Diabetes. D.J. Selen et al. Diabetes Care 2023;46(1):83–91. https://doi.org/10.2337/dc22-1390.
Low-Dose Empagliflozin as Adjunct to Hybrid Closed-Loop Insulin Therapy in Adults With Suboptimally Controlled Type 1 Diabetes: A Randomized Crossover Controlled Trial. M.R. Pasqua et al. Diabetes Care 2023;46(1):165–172. https://doi.org/10.2337/dc22-0490.
Long-term Weight Training and Mortality in U.S. Male Health Professionals With and Without Type 2 Diabetes. D.H. Lee at al. Diabetes Care 2023;46(1):138–148. https://doi.org/10.2337/dc21-2420.
About the Hosts
Alice Cheng, MD, FRCPC, is an Endocrinologist at Trillium Health Partners and Unity Health Toronto and an Associate Professor at the University of Toronto. She has been involved with the development of the Diabetes Canada clinical practice guidelines since 2003 and served as Chair for the 2013 version. She is Past-Chair of the Professional Section of Diabetes Canada and is currently Chair of the Scientific Planning Committee for the 2023 and 2024 American Diabetes Association annual scientific meetings. In recognition of her contribution to the diabetes community, she has received the national Charles H. Best Award and the Gerald S. Wong Service Award from Diabetes Canada. She is also the creator of The Med Ed Pledge – an initiative to increase Diversity & Inclusion in continuing medical education (www.theMedEdPledge.com) and the CMEX (Continuing Medical Education eXperts) – a searchable database of health care professionals interested in participating in medical education.
Michael R. Rickels, MD, MS, is an Endocrinologist at the Hospital of the University of Pennsylvania and the
Willard and Rhoda Ware Professor in Diabetes and Metabolic Diseases at the University of Pennsylvania Perelman School of Medicine. He conducts patient-oriented diabetes research that aims at understanding the pathophysiology of various forms of diabetes and the in vivo mechanisms of new diabetes treatments, with a focus on islet function and replacement and glucose counterregulation in type 1 diabetes and pancreatogenic forms of diabetes. Dr. Rickels’ research has been continuously funded by the National Institutes of Health where he has served as a permanent member of the Clinical and Integrative Diabetes and Obesity Study Section (2014-2018), and has been recognized by service as Vice-Chair for the Type 1 Diabetes Exchange Clinic Network and Registry (2015-2019), as elected councilor for the International Pancreas & Islet Transplant Association (2015-2021), as Associate Editor of Endocrine Reviews (2015-2018), as a member of the American Diabetes Association’s Scientific Sessions Planning Committee (2012-2014; 2020-2022).